Antihypertensive activity of 6-O-galloyl-D-glucose, a phenolic glycoside from Sapium sebiferum

Feng Lin Hsu, Yung Yung Lee, Juei Tang Cheng

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

The antihypertensive activity of a phenolic glycoside contained in the leaves of Sapium sebiferum was investigated. From intravenous screening using spontaneously hypertensive rats, 6-O-galloyl-D-glucose was identified as an active substance. The hypotensive action of this compound appears to be produced by an inhibition of noradrenaline release and/or a direct vasodilatation.

Original languageEnglish
Pages (from-to)308-312
Number of pages5
JournalJournal of Natural Products
Volume57
Issue number2
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Plant Science
  • Chemistry (miscellaneous)
  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

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