Antidiabetic dimeric guianolides and a lignan glycoside from Lactuca indica

Chia Chung Hou, Shwu Jiuan Lin, Juei Tang Cheng, Feng-Lin Hsu

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Three novel sesquiterpene lactones, lactucain A (1), B (2), and C (3), and a new furofuran lignan, lactucaside (4), were isolated from Lactuca indica along with nine known compounds, 11β,13-dihydrolactucin, cichoriosides B, quercetin, quercetin 3-O-glucoside, rutin, apigenin, luteolin, luteolin 7-O-glucuronide, and chlorogenic acid. Among these compounds, latucain C (3) and lactucaside (4) showed significant antidiabetic activity.

Original languageEnglish
Pages (from-to)625-629
Number of pages5
JournalJournal of Natural Products
Volume66
Issue number5
DOIs
Publication statusPublished - May 1 2003

ASJC Scopus subject areas

  • Plant Science
  • Chemistry (miscellaneous)
  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

Fingerprint Dive into the research topics of 'Antidiabetic dimeric guianolides and a lignan glycoside from Lactuca indica'. Together they form a unique fingerprint.

  • Cite this