Anti-obesity effects of gut microbiota are associated with lactic acid bacteria

Yueh Ting Tsai, Po Ching Cheng, Tzu Ming Pan

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

The prevalence of obesity is rapidly becoming endemic in industrialized countries and continues to increase in developing countries worldwide. Obesity predisposes people to an increased risk of developing metabolic syndrome. Recent studies have described an association between obesity and certain gut microbiota, suggesting that gut microbiota might play a critical role in the development of obesity. Although probiotics have many beneficial health effects in humans and animals, attention has only recently been drawn to manipulating the gut microbiota, such as lactic acid bacteria (LAB), to influence the development of obesity. In this review, we first describe the causes of obesity, including the genetic and environmental factors. We then describe the relationship between the gut microbiota and obesity, and the mechanisms by which the gut microbiota influence energy metabolism and inflammation in obesity. Lastly, we focus on the potential role of LAB in mediating the effects of the gut microbiota in the development of obesity.

Original languageEnglish
Pages (from-to)1-10
Number of pages10
JournalApplied Microbiology and Biotechnology
Volume98
Issue number1
DOIs
Publication statusPublished - 2014

Fingerprint

Lactic Acid
Obesity
Bacteria
Gastrointestinal Microbiome
Probiotics
Developed Countries
Energy Metabolism
Developing Countries
Inflammation
Health

Keywords

  • Anti-obesity effects
  • Gut microbiota
  • Lactic acid bacteria
  • Lipid metabolism
  • Probiotics

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology

Cite this

Anti-obesity effects of gut microbiota are associated with lactic acid bacteria. / Tsai, Yueh Ting; Cheng, Po Ching; Pan, Tzu Ming.

In: Applied Microbiology and Biotechnology, Vol. 98, No. 1, 2014, p. 1-10.

Research output: Contribution to journalArticle

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