Abstract
The prevalence of obesity is rapidly becoming endemic in industrialized countries and continues to increase in developing countries worldwide. Obesity predisposes people to an increased risk of developing metabolic syndrome. Recent studies have described an association between obesity and certain gut microbiota, suggesting that gut microbiota might play a critical role in the development of obesity. Although probiotics have many beneficial health effects in humans and animals, attention has only recently been drawn to manipulating the gut microbiota, such as lactic acid bacteria (LAB), to influence the development of obesity. In this review, we first describe the causes of obesity, including the genetic and environmental factors. We then describe the relationship between the gut microbiota and obesity, and the mechanisms by which the gut microbiota influence energy metabolism and inflammation in obesity. Lastly, we focus on the potential role of LAB in mediating the effects of the gut microbiota in the development of obesity.
| Original language | English |
|---|---|
| Pages (from-to) | 1-10 |
| Number of pages | 10 |
| Journal | Applied Microbiology and Biotechnology |
| Volume | 98 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2014 |
Fingerprint
Keywords
- Anti-obesity effects
- Gut microbiota
- Lactic acid bacteria
- Lipid metabolism
- Probiotics
ASJC Scopus subject areas
- Biotechnology
- Applied Microbiology and Biotechnology
Cite this
Anti-obesity effects of gut microbiota are associated with lactic acid bacteria. / Tsai, Yueh Ting; Cheng, Po Ching; Pan, Tzu Ming.
In: Applied Microbiology and Biotechnology, Vol. 98, No. 1, 2014, p. 1-10.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Anti-obesity effects of gut microbiota are associated with lactic acid bacteria
AU - Tsai, Yueh Ting
AU - Cheng, Po Ching
AU - Pan, Tzu Ming
PY - 2014
Y1 - 2014
N2 - The prevalence of obesity is rapidly becoming endemic in industrialized countries and continues to increase in developing countries worldwide. Obesity predisposes people to an increased risk of developing metabolic syndrome. Recent studies have described an association between obesity and certain gut microbiota, suggesting that gut microbiota might play a critical role in the development of obesity. Although probiotics have many beneficial health effects in humans and animals, attention has only recently been drawn to manipulating the gut microbiota, such as lactic acid bacteria (LAB), to influence the development of obesity. In this review, we first describe the causes of obesity, including the genetic and environmental factors. We then describe the relationship between the gut microbiota and obesity, and the mechanisms by which the gut microbiota influence energy metabolism and inflammation in obesity. Lastly, we focus on the potential role of LAB in mediating the effects of the gut microbiota in the development of obesity.
AB - The prevalence of obesity is rapidly becoming endemic in industrialized countries and continues to increase in developing countries worldwide. Obesity predisposes people to an increased risk of developing metabolic syndrome. Recent studies have described an association between obesity and certain gut microbiota, suggesting that gut microbiota might play a critical role in the development of obesity. Although probiotics have many beneficial health effects in humans and animals, attention has only recently been drawn to manipulating the gut microbiota, such as lactic acid bacteria (LAB), to influence the development of obesity. In this review, we first describe the causes of obesity, including the genetic and environmental factors. We then describe the relationship between the gut microbiota and obesity, and the mechanisms by which the gut microbiota influence energy metabolism and inflammation in obesity. Lastly, we focus on the potential role of LAB in mediating the effects of the gut microbiota in the development of obesity.
KW - Anti-obesity effects
KW - Gut microbiota
KW - Lactic acid bacteria
KW - Lipid metabolism
KW - Probiotics
UR - http://www.scopus.com/inward/record.url?scp=84891848319&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84891848319&partnerID=8YFLogxK
U2 - 10.1007/s00253-013-5346-3
DO - 10.1007/s00253-013-5346-3
M3 - Article
C2 - 24232731
AN - SCOPUS:84891848319
VL - 98
SP - 1
EP - 10
JO - Applied Microbiology and Biotechnology
JF - Applied Microbiology and Biotechnology
SN - 0175-7598
IS - 1
ER -