Anti-obesity drug use before professional treatment in Taiwan

Tsan Hon Liou, Chih Hsing Wu, Shu-Chen Chien, Wen Yuan Lin, Wei Jei Lee, Pesus Chou

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Between July 2004 and June 2005, a cross-sectional study was performed to determine the prevalence and patterns of anti-obesity medicine use among subjects seeking obesity treatment in Taiwan. Eighteen obesity outpatient clinics were selected via a random stratified sampling method and 1,060 first-visit clients (791 females and 269 males) aged above 18 years were enrolled and then completed a self-administered questionnaire. The prevalence of anti-obesity medicine use was 50.8%; more females than male used anti-obesity medicines (53.6% vs. 42.4%). Of the 1,060 subjects, 17.1% had used orlistat, 21.1% had taken sibutramine, and 18.3% had utilized unproven drugs such as cocktail therapy and other anti-obesity drugs. Furthermore, 23.6% and 22.4% of subjects indicated that they concurrently used Chinese herbal preparations and dietary supplements, respectively. Logistic regression analyses demonstrated that the odds ratio (OR) for anti-obesity medicine use was substantially higher in females (OR, 1.9; 95% CI, 1.3-2.6), those aged 18-24 years (OR, 1.6; 95% CI, 1.0-2.6), those with a body mass index (BMI) >35 kg/m2 (OR, 3.4; 95% CI, 2.1-5.7) and respondents concurrently using Chinese herbal preparations (OR, 1.7; 95% CI, 1.2-2.4) and dietary supplements (OR, 2.2; 95% CI, 1.6-3.1). In conclusion, the prevalence of anti-obesity drugs use is high among Taiwanese adults before they seek obesity treatment. Young, obese females, and those who had taken Chinese herbal preparations/dietary supplements had a high likelihood to report using anti-obesity medicines. Use of unproven weight-loss drugs is common and warrants further investigation.

Original languageEnglish
Pages (from-to)580-586
Number of pages7
JournalAsia Pacific Journal of Clinical Nutrition
Volume16
Issue number3
Publication statusPublished - Sep 2007

Fingerprint

Anti-Obesity Agents
Taiwan
Obesity
Odds Ratio
Plant Preparations
Dietary Supplements
sibutramine
Medicine
Ambulatory Care Facilities
Body Mass Index
Therapeutics
Cross-Sectional Studies
Logistic Models
Regression Analysis

Keywords

  • Dietary supplement
  • Drug utilization
  • Off-label drugs
  • Orlistat
  • Sibutramine

ASJC Scopus subject areas

  • Medicine (miscellaneous)

Cite this

Anti-obesity drug use before professional treatment in Taiwan. / Liou, Tsan Hon; Wu, Chih Hsing; Chien, Shu-Chen; Lin, Wen Yuan; Lee, Wei Jei; Chou, Pesus.

In: Asia Pacific Journal of Clinical Nutrition, Vol. 16, No. 3, 09.2007, p. 580-586.

Research output: Contribution to journalArticle

Liou, Tsan Hon ; Wu, Chih Hsing ; Chien, Shu-Chen ; Lin, Wen Yuan ; Lee, Wei Jei ; Chou, Pesus. / Anti-obesity drug use before professional treatment in Taiwan. In: Asia Pacific Journal of Clinical Nutrition. 2007 ; Vol. 16, No. 3. pp. 580-586.
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abstract = "Between July 2004 and June 2005, a cross-sectional study was performed to determine the prevalence and patterns of anti-obesity medicine use among subjects seeking obesity treatment in Taiwan. Eighteen obesity outpatient clinics were selected via a random stratified sampling method and 1,060 first-visit clients (791 females and 269 males) aged above 18 years were enrolled and then completed a self-administered questionnaire. The prevalence of anti-obesity medicine use was 50.8{\%}; more females than male used anti-obesity medicines (53.6{\%} vs. 42.4{\%}). Of the 1,060 subjects, 17.1{\%} had used orlistat, 21.1{\%} had taken sibutramine, and 18.3{\%} had utilized unproven drugs such as cocktail therapy and other anti-obesity drugs. Furthermore, 23.6{\%} and 22.4{\%} of subjects indicated that they concurrently used Chinese herbal preparations and dietary supplements, respectively. Logistic regression analyses demonstrated that the odds ratio (OR) for anti-obesity medicine use was substantially higher in females (OR, 1.9; 95{\%} CI, 1.3-2.6), those aged 18-24 years (OR, 1.6; 95{\%} CI, 1.0-2.6), those with a body mass index (BMI) >35 kg/m2 (OR, 3.4; 95{\%} CI, 2.1-5.7) and respondents concurrently using Chinese herbal preparations (OR, 1.7; 95{\%} CI, 1.2-2.4) and dietary supplements (OR, 2.2; 95{\%} CI, 1.6-3.1). In conclusion, the prevalence of anti-obesity drugs use is high among Taiwanese adults before they seek obesity treatment. Young, obese females, and those who had taken Chinese herbal preparations/dietary supplements had a high likelihood to report using anti-obesity medicines. Use of unproven weight-loss drugs is common and warrants further investigation.",
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