Abstract
In this study, chemical compositions of hydrodistilled essential oil and anti-inflammatory activities from the twigs of Cinnamomum osmophloeum Kaneh. were investigated for the first time. The chemical constituents of the twig essential oil were further analyzed by GC-MS and they were found to be l-bornyl acetate (15.89%), caryophyllene oxide (12.98%), γ-eudesmol (8.03%), β-caryophyllene (6.60%), T-cadinol (5.49%), δ-cadinene (4.79%), trans-β-elemenone (4.25%), cadalene (4.19%), and trans-cinnamaldehyde (4.07%). The effects of essential oil on nitric oxide (NO) and prostaglandin E2 (PGE2) production in lipopolysaccharide (LPS)-activated RAW 264.7 macrophages were also examined. Results of nitric oxide tests indicated that twig essential oil and its major constituents such as trans-cinnamaldehyde, caryophyllene oxide, l-borneol, l-bornyl acetate, eugenol, β-caryophyllene, E-nerolidol, and cinnamyl acetate have excellent activities. These findings demonstrated that essential oil of C. osmophloeum twigs have excellent anti-inflammatory activities and thus have great potential to be used as a source for natural health products.
Original language | English |
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Pages (from-to) | 3908-3913 |
Number of pages | 6 |
Journal | Bioresource Technology |
Volume | 99 |
Issue number | 9 |
DOIs | |
Publication status | Published - Jun 2008 |
Externally published | Yes |
Keywords
- Anti-inflammation
- Cinnamomum osmophloeum
- Essential oil
- trans-Cinnamaldehyde
- Twigs
ASJC Scopus subject areas
- Agronomy and Crop Science
- Food Science
- Process Chemistry and Technology
- Applied Microbiology and Biotechnology