Abstract
In this study, chemical compositions of hydrodistilled essential oil and anti-inflammatory activities from the twigs of Cinnamomum osmophloeum Kaneh. were investigated for the first time. The chemical constituents of the twig essential oil were further analyzed by GC-MS and they were found to be l-bornyl acetate (15.89%), caryophyllene oxide (12.98%), γ-eudesmol (8.03%), β-caryophyllene (6.60%), T-cadinol (5.49%), δ-cadinene (4.79%), trans-β-elemenone (4.25%), cadalene (4.19%), and trans-cinnamaldehyde (4.07%). The effects of essential oil on nitric oxide (NO) and prostaglandin E2 (PGE2) production in lipopolysaccharide (LPS)-activated RAW 264.7 macrophages were also examined. Results of nitric oxide tests indicated that twig essential oil and its major constituents such as trans-cinnamaldehyde, caryophyllene oxide, l-borneol, l-bornyl acetate, eugenol, β-caryophyllene, E-nerolidol, and cinnamyl acetate have excellent activities. These findings demonstrated that essential oil of C. osmophloeum twigs have excellent anti-inflammatory activities and thus have great potential to be used as a source for natural health products.
| Original language | English |
|---|---|
| Pages (from-to) | 3908-3913 |
| Number of pages | 6 |
| Journal | Bioresource Technology |
| Volume | 99 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - Jun 2008 |
| Externally published | Yes |
Fingerprint
Keywords
- Anti-inflammation
- Cinnamomum osmophloeum
- Essential oil
- trans-Cinnamaldehyde
- Twigs
ASJC Scopus subject areas
- Agronomy and Crop Science
- Food Science
- Process Chemistry and Technology
- Applied Microbiology and Biotechnology
Cite this
Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs. / Tung, Yu Tang; Chua, Meng Thong; Wang, Sheng Yang; Chang, Shang Tzen.
In: Bioresource Technology, Vol. 99, No. 9, 06.2008, p. 3908-3913.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs
AU - Tung, Yu Tang
AU - Chua, Meng Thong
AU - Wang, Sheng Yang
AU - Chang, Shang Tzen
PY - 2008/6
Y1 - 2008/6
N2 - In this study, chemical compositions of hydrodistilled essential oil and anti-inflammatory activities from the twigs of Cinnamomum osmophloeum Kaneh. were investigated for the first time. The chemical constituents of the twig essential oil were further analyzed by GC-MS and they were found to be l-bornyl acetate (15.89%), caryophyllene oxide (12.98%), γ-eudesmol (8.03%), β-caryophyllene (6.60%), T-cadinol (5.49%), δ-cadinene (4.79%), trans-β-elemenone (4.25%), cadalene (4.19%), and trans-cinnamaldehyde (4.07%). The effects of essential oil on nitric oxide (NO) and prostaglandin E2 (PGE2) production in lipopolysaccharide (LPS)-activated RAW 264.7 macrophages were also examined. Results of nitric oxide tests indicated that twig essential oil and its major constituents such as trans-cinnamaldehyde, caryophyllene oxide, l-borneol, l-bornyl acetate, eugenol, β-caryophyllene, E-nerolidol, and cinnamyl acetate have excellent activities. These findings demonstrated that essential oil of C. osmophloeum twigs have excellent anti-inflammatory activities and thus have great potential to be used as a source for natural health products.
AB - In this study, chemical compositions of hydrodistilled essential oil and anti-inflammatory activities from the twigs of Cinnamomum osmophloeum Kaneh. were investigated for the first time. The chemical constituents of the twig essential oil were further analyzed by GC-MS and they were found to be l-bornyl acetate (15.89%), caryophyllene oxide (12.98%), γ-eudesmol (8.03%), β-caryophyllene (6.60%), T-cadinol (5.49%), δ-cadinene (4.79%), trans-β-elemenone (4.25%), cadalene (4.19%), and trans-cinnamaldehyde (4.07%). The effects of essential oil on nitric oxide (NO) and prostaglandin E2 (PGE2) production in lipopolysaccharide (LPS)-activated RAW 264.7 macrophages were also examined. Results of nitric oxide tests indicated that twig essential oil and its major constituents such as trans-cinnamaldehyde, caryophyllene oxide, l-borneol, l-bornyl acetate, eugenol, β-caryophyllene, E-nerolidol, and cinnamyl acetate have excellent activities. These findings demonstrated that essential oil of C. osmophloeum twigs have excellent anti-inflammatory activities and thus have great potential to be used as a source for natural health products.
KW - Anti-inflammation
KW - Cinnamomum osmophloeum
KW - Essential oil
KW - trans-Cinnamaldehyde
KW - Twigs
UR - http://www.scopus.com/inward/record.url?scp=43849093857&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=43849093857&partnerID=8YFLogxK
U2 - 10.1016/j.biortech.2007.07.050
DO - 10.1016/j.biortech.2007.07.050
M3 - Article
VL - 99
SP - 3908
EP - 3913
JO - Bioresource Technology
JF - Bioresource Technology
SN - 0960-8524
IS - 9
ER -