Angiomyomatous hamartoma in an inguinal lymph node with proliferating pericytes/smooth muscle cells, plexiform vessel tangles, and ectopic calcification

Chii Hong Lee, Tung Cheng Chang, Jan Wen Ku

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Angiomyomatous hamartoma (AMH) is a rare benign lesion, which occurs almost exclusively in the inguinal lymph nodes. We herein report a case of a female elder who presented with a long-standing inguinal mass. Microscopically, the mass showed a zonal distribution, characterized by thick-walled muscular vessels, fibrosis, and calcification in the hilum and proliferating spindle cells around thin-walled vessels and plexiform vessel tangles at the periphery. The spindle cells show positive immunoreactivity of smooth muscle actin and CD34 with a heterogeneous expression of desmin and CD44. Although the pathogenesis of AMH remains uncertain, the histological features and immunohistochemical findings of this case imply a disordered or exuberant angiogenic process.

Original languageEnglish
Pages (from-to)226-228
Number of pages3
JournalIndian Journal of Pathology and Microbiology
Volume58
Issue number2
DOIs
Publication statusPublished - Apr 1 2015

Keywords

  • Angiomyomatous hamartoma
  • Ectopic calcification
  • Inguinal lymph node
  • Pericyte
  • Plexiform vessel

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Microbiology (medical)

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