Anesthetic management of a patient with congenital methemoglobinemia

Chiao Y. Lin, Jenn Ming Yang, Chiun Ting Chen, Yung W. Hsu, Chun J. Huang, Chien Chuan Chen, Hsin Jung Tsai

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Methemoglobinemia occasionally causes cyanosis particularly in congenital methemoglobinemia. Avoidance of exposure to oxidizing agents is important for patients with congenital methemoglobinemia because of their deficient enzymatic pathways and decreased oxygen-carrying capacity. Here, we present a patient with preoperatively undiagnosed congenital methemoglobinemia who underwent uterine myomectomy under general anesthesia. The patient was a 35-year-old woman who displayed a low pulse oximetry reading of 91% prior to induction of anesthesia. Methemoglobinemia was first suspected intraoperatively because of a mismatch of SpO2 of finger pulse oximetry and SaO2 of arterial blood, and was later confirmed by multiple-wavelength CO-oximetry. The pathophysiology, etiology, clinical manifestations, anesthetic considerations, and treatment options of methemoglobinemia are discussed.

Original languageEnglish
Pages (from-to)143-146
Number of pages4
JournalActa Anaesthesiologica Taiwanica
Volume47
Issue number3
DOIs
Publication statusPublished - Sep 2009
Externally publishedYes

Fingerprint

Methemoglobinemia
Oximetry
Anesthetics
Uterine Myomectomy
Cyanosis
Conservation of Natural Resources
Carbon Monoxide
Oxidants
General Anesthesia
Fingers
Reading
Anesthesia
Oxygen
Congenital Methemoglobinemia
Therapeutics

Keywords

  • Methemoglobinemia: congenital
  • Oxygen: saturation

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Lin, C. Y., Yang, J. M., Chen, C. T., Hsu, Y. W., Huang, C. J., Chen, C. C., & Tsai, H. J. (2009). Anesthetic management of a patient with congenital methemoglobinemia. Acta Anaesthesiologica Taiwanica, 47(3), 143-146. https://doi.org/10.1016/S1875-4597(09)60042-4

Anesthetic management of a patient with congenital methemoglobinemia. / Lin, Chiao Y.; Yang, Jenn Ming; Chen, Chiun Ting; Hsu, Yung W.; Huang, Chun J.; Chen, Chien Chuan; Tsai, Hsin Jung.

In: Acta Anaesthesiologica Taiwanica, Vol. 47, No. 3, 09.2009, p. 143-146.

Research output: Contribution to journalArticle

Lin, Chiao Y. ; Yang, Jenn Ming ; Chen, Chiun Ting ; Hsu, Yung W. ; Huang, Chun J. ; Chen, Chien Chuan ; Tsai, Hsin Jung. / Anesthetic management of a patient with congenital methemoglobinemia. In: Acta Anaesthesiologica Taiwanica. 2009 ; Vol. 47, No. 3. pp. 143-146.
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