An unusual complication following transarterial chemoembolization: Acute myocardial infarction

Yi-Liang Lai, Wei-Chou Chang, Wu-Hsien Kuo, Tien-Yu Huang, Heng-Cheng Chu, Tsai-Yuan Hsieh, Wei-Kuo Chang

Research output: Contribution to journal › Article

Abstract

Transarterial chemoembolization has been widely used to treat unresectable hepatocellular carcinoma. Various complications have been reported, but they have not included acute myocardial infarction. Acute myocardial infarction results mainly from coronary artery occlusion by plaques that are vulnerable to rupture or from coronary spasm, embolization, or dissection of the coronary artery. It is associated with significant morbidity and mortality. We present a case report that describes a patient with hepatocellular carcinoma who underwent transarterial chemoembolization and died subsequently of acute myocardial infarction. To our knowledge, there has been no previous report of this complication induced by transarterial chemoembolization for hepatocellular carcinoma. This case illustrates the need to be aware of acute myocardial infarction when transarterial chemoembolization is planned for the treatment of hepatocellular carcinoma, especially in patients with underlying coronary artery disease. © 2009 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE).
Original languageEnglish
Pages (from-to)196-200
Number of pages5
JournalCardioVascular and Interventional Radiology
Volume33
Issue number1
DOIs
Publication statusPublished - 2010
Externally publishedYes

Fingerprint

Hepatocellular Carcinoma
Myocardial Infarction
Coronary Vessels
Coronary Occlusion
Spasm
Dissection
Coronary Artery Disease
Rupture
Morbidity
Mortality
Therapeutics

Keywords

  • Acute myocardial infarction
  • Hepatocellular carcinoma
  • Transarterial chemoembolization
  • doxorubicin
  • gelfoam
  • iodinated poppyseed oil
  • pethidine
  • abdominal pain
  • acute heart infarction
  • adult
  • anorexia
  • article
  • case report
  • cause of death
  • chemoembolization
  • cold sweat
  • dyspnea
  • hepatic artery
  • human
  • liver cell carcinoma
  • male
  • priority journal
  • ST segment elevation
  • thorax pain
  • tumor thrombus
  • weight reduction
  • Arterial Occlusive Diseases
  • Carcinoma, Hepatocellular
  • Chemoembolization, Therapeutic
  • Cholecystitis
  • Coronary Disease
  • Diabetes Mellitus, Type 2
  • Doxorubicin
  • Fatal Outcome
  • Hepatic Artery
  • Hepatitis B, Chronic
  • Humans
  • Iodized Oil
  • Liver Neoplasms
  • Male
  • Middle Aged
  • Myocardial Infarction

Cite this

An unusual complication following transarterial chemoembolization: Acute myocardial infarction. / Lai, Yi-Liang; Chang, Wei-Chou; Kuo, Wu-Hsien; Huang, Tien-Yu; Chu, Heng-Cheng; Hsieh, Tsai-Yuan; Chang, Wei-Kuo.

In: CardioVascular and Interventional Radiology, Vol. 33, No. 1, 2010, p. 196-200.

Research output: Contribution to journal › Article

Lai, Y-L, Chang, W-C, Kuo, W-H, Huang, T-Y, Chu, H-C, Hsieh, T-Y & Chang, W-K 2010, 'An unusual complication following transarterial chemoembolization: Acute myocardial infarction', CardioVascular and Interventional Radiology, vol. 33, no. 1, pp. 196-200. https://doi.org/10.1007/s00270-009-9683-7
Lai Y-L, Chang W-C, Kuo W-H, Huang T-Y, Chu H-C, Hsieh T-Y et al. An unusual complication following transarterial chemoembolization: Acute myocardial infarction. CardioVascular and Interventional Radiology. 2010;33(1):196-200. https://doi.org/10.1007/s00270-009-9683-7
Lai, Yi-Liang ; Chang, Wei-Chou ; Kuo, Wu-Hsien ; Huang, Tien-Yu ; Chu, Heng-Cheng ; Hsieh, Tsai-Yuan ; Chang, Wei-Kuo. / An unusual complication following transarterial chemoembolization: Acute myocardial infarction. In: CardioVascular and Interventional Radiology. 2010 ; Vol. 33, No. 1. pp. 196-200.
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abstract = "Transarterial chemoembolization has been widely used to treat unresectable hepatocellular carcinoma. Various complications have been reported, but they have not included acute myocardial infarction. Acute myocardial infarction results mainly from coronary artery occlusion by plaques that are vulnerable to rupture or from coronary spasm, embolization, or dissection of the coronary artery. It is associated with significant morbidity and mortality. We present a case report that describes a patient with hepatocellular carcinoma who underwent transarterial chemoembolization and died subsequently of acute myocardial infarction. To our knowledge, there has been no previous report of this complication induced by transarterial chemoembolization for hepatocellular carcinoma. This case illustrates the need to be aware of acute myocardial infarction when transarterial chemoembolization is planned for the treatment of hepatocellular carcinoma, especially in patients with underlying coronary artery disease. {\circledC} 2009 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE).",
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author = "Yi-Liang Lai and Wei-Chou Chang and Wu-Hsien Kuo and Tien-Yu Huang and Heng-Cheng Chu and Tsai-Yuan Hsieh and Wei-Kuo Chang",
note = "Export Date: 22 March 2016 CODEN: CARAD 通訊地址: Chang, W.-K.; Department of Internal Medicine, National Defense Medical Center, Tri-Service General Hospital, 325 Cheng-Kung Road, Sec. 2, Neihu, Taipei, Taiwan; 電子郵件： chougo2002@yahoo.com.tw 化學物質/CAS: doxorubicin, 23214-92-8, 25316-40-9; iodinated poppyseed oil, 8001-40-9, 8002-46-8, 8006-56-2, 8006-57-3; pethidine, 28097-96-3, 50-13-5, 57-42-1; Doxorubicin, 23214-92-8; Iodized Oil, 8001-40-9 商標： adriamycin; demerol 參考文獻: Bosch, F.X., Ribes, J., Diaz, M., Cleries, R., Primary liver cancer: Worldwide incidence and trends (2004) Gastroenterology, 127 (SUPPL.), pp. S5-S16. , DOI 10.1053/j.gastro.2004.09.011, PII S0016508504015902; Bruix, J., Sherman, M., Management of hepatocellular carcinoma (2005) Hepatology, 42 (5), pp. 1208-1236. , DOI 10.1002/hep.20933; Yamada, R., Sato, M., Kawabata, M., Hepatic artery embolization in 120 patients with unresectable hepatoma (1983) Radiology, 148 (2), pp. 397-401. , 1:STN:280:DyaL3s3kvVWhsA{\%}3D{\%}3D 6306721; Liapi, E., Georgiades, C.C., Hong, K., Geschwind, J.-F.H., Transcatheter Arterial Chemoembolization: Current Technique and Future Promise (2007) Techniques in Vascular and Interventional Radiology, 10 (1), pp. 2-11. , DOI 10.1053/j.tvir.2007.08.008, PII S1089251607000704, Interventional Oncology - Part 1: Hepatic Interventions; Lau, W.Y., Yu, S.C.H., Lai, E.C.H., Leung, T.W.T., Transarterial chemoembolization for hepatocellular carcinoma (2006) Journal of the American College of Surgeons, 202 (1), pp. 155-168. , DOI 10.1016/j.jamcollsurg.2005.06.263, PII S1072751505009890; Ahrar, K., Gupta, S., Hepatic artery embolization for hepatocellular carcinoma: Technique, patient selection, and outcomes (2003) Surgical Oncology Clinics of North America, 12 (1), pp. 105-126. , DOI 10.1016/S1055-3207(02)00089-3, PII S1055320702000893; Kokudo, N., Makuuchi, M., Current role of portal vein embolization/hepatic artery chemoembolization (2004) Surgical Clinics of North America, 84 (2), pp. 643-657. , DOI 10.1016/j.suc.2003.12.004, PII S0039610903002408; Del Pozo, A.C., Lopez, P., Management of hepatocellular carcinoma (2007) Clinics in Liver Disease, 11 (2), pp. 305-321. , DOI 10.1016/j.cld.2007.04.007, PII S1089326107000220, Liver Transplantation; Kothary, N., Weintraub, J.L., Susman, J., Rundback, J.H., Transarterial Chemoembolization for Primary Hepatocellular Carcinoma in Patients at High Risk (2007) Journal of Vascular and Interventional Radiology, 18 (12), pp. 1517-1526. , DOI 10.1016/j.jvir.2007.07.035, PII S105104430701113X; Yen, F.S., Wu, J.C., Kuo, B.I., Transcatheter arterial embolization for hepatocellular carcinoma with portal vein thrombosis (1995) J Gastroenterol Hepatol, 10 (3), pp. 237-240. , 10.1111/j.1440-1746.1995.tb01086.x 1:STN:280:DyaK28{\%}2FitlCgsw{\%}3D{\%}3D 7548796; Chung, J.W., Park, J.H., Han, J.K., Hepatic tumors: Predisposing factors for complications of transcatheter oily chemoembolization (1996) Radiology, 198 (1), pp. 33-40. , 1:STN:280:DyaK287itlWguw{\%}3D{\%}3D 8539401; White, H.D., Chew, D.P., Acute myocardial infarction (2008) Lancet, 372 (9638), pp. 570-584. , 10.1016/S0140-6736(08)61237-4 1:CAS:528:DC{\%}2BD1cXpvFKgsLg{\%}3D 18707987; Calvo-Romero, J.M., Fern{\'a}ndez-Soria-Pantoja, R., Arrebola-Garcia, J.D., Ischemic heart disease associated with vincristine and doxorubicin chemotherapy (2001) Ann Pharmacother, 35 (11), pp. 1403-1405. , 10.1345/aph.10358 1:STN:280:DC{\%}2BD3MnnslKitg{\%}3D{\%}3D 11724093; McCord, J.M., Oxygen-derived free radicals in postischemic tissue injury (1989) N Engl J Med, 312, pp. 159-163; Lu, W., Li, Y.H., He, X.F., Necrosis and apoptosis in hepatocellular carcinoma following low-dose versus high-dose preoperative chemoembolization (2008) Cardiovasc Interv Radiol, 31 (6), pp. 1133-1140. , 10.1007/s00270-008-9379-4; Kasugai, H., Kojima, J., Tatsuta, M., Treatment of hepatocellular carcinoma by transcatheter arterial embolization combined with intraarterial infusion of a mixture of cisplatin and ethiodized oil (1989) Gastroenterology, 97 (4), pp. 965-971. , 1:STN:280:DyaL1MznvVKktw{\%}3D{\%}3D 2550311",
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doi = "10.1007/s00270-009-9683-7",
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TY - JOUR

T1 - An unusual complication following transarterial chemoembolization: Acute myocardial infarction

AU - Lai, Yi-Liang

AU - Chang, Wei-Chou

AU - Kuo, Wu-Hsien

AU - Huang, Tien-Yu

AU - Chu, Heng-Cheng

AU - Hsieh, Tsai-Yuan

AU - Chang, Wei-Kuo

N1 - Export Date: 22 March 2016 CODEN: CARAD 通訊地址: Chang, W.-K.; Department of Internal Medicine, National Defense Medical Center, Tri-Service General Hospital, 325 Cheng-Kung Road, Sec. 2, Neihu, Taipei, Taiwan; 電子郵件： chougo2002@yahoo.com.tw 化學物質/CAS: doxorubicin, 23214-92-8, 25316-40-9; iodinated poppyseed oil, 8001-40-9, 8002-46-8, 8006-56-2, 8006-57-3; pethidine, 28097-96-3, 50-13-5, 57-42-1; Doxorubicin, 23214-92-8; Iodized Oil, 8001-40-9 商標： adriamycin; demerol 參考文獻: Bosch, F.X., Ribes, J., Diaz, M., Cleries, R., Primary liver cancer: Worldwide incidence and trends (2004) Gastroenterology, 127 (SUPPL.), pp. S5-S16. , DOI 10.1053/j.gastro.2004.09.011, PII S0016508504015902; Bruix, J., Sherman, M., Management of hepatocellular carcinoma (2005) Hepatology, 42 (5), pp. 1208-1236. , DOI 10.1002/hep.20933; Yamada, R., Sato, M., Kawabata, M., Hepatic artery embolization in 120 patients with unresectable hepatoma (1983) Radiology, 148 (2), pp. 397-401. , 1:STN:280:DyaL3s3kvVWhsA%3D%3D 6306721; Liapi, E., Georgiades, C.C., Hong, K., Geschwind, J.-F.H., Transcatheter Arterial Chemoembolization: Current Technique and Future Promise (2007) Techniques in Vascular and Interventional Radiology, 10 (1), pp. 2-11. , DOI 10.1053/j.tvir.2007.08.008, PII S1089251607000704, Interventional Oncology - Part 1: Hepatic Interventions; Lau, W.Y., Yu, S.C.H., Lai, E.C.H., Leung, T.W.T., Transarterial chemoembolization for hepatocellular carcinoma (2006) Journal of the American College of Surgeons, 202 (1), pp. 155-168. , DOI 10.1016/j.jamcollsurg.2005.06.263, PII S1072751505009890; Ahrar, K., Gupta, S., Hepatic artery embolization for hepatocellular carcinoma: Technique, patient selection, and outcomes (2003) Surgical Oncology Clinics of North America, 12 (1), pp. 105-126. , DOI 10.1016/S1055-3207(02)00089-3, PII S1055320702000893; Kokudo, N., Makuuchi, M., Current role of portal vein embolization/hepatic artery chemoembolization (2004) Surgical Clinics of North America, 84 (2), pp. 643-657. , DOI 10.1016/j.suc.2003.12.004, PII S0039610903002408; Del Pozo, A.C., Lopez, P., Management of hepatocellular carcinoma (2007) Clinics in Liver Disease, 11 (2), pp. 305-321. , DOI 10.1016/j.cld.2007.04.007, PII S1089326107000220, Liver Transplantation; Kothary, N., Weintraub, J.L., Susman, J., Rundback, J.H., Transarterial Chemoembolization for Primary Hepatocellular Carcinoma in Patients at High Risk (2007) Journal of Vascular and Interventional Radiology, 18 (12), pp. 1517-1526. , DOI 10.1016/j.jvir.2007.07.035, PII S105104430701113X; Yen, F.S., Wu, J.C., Kuo, B.I., Transcatheter arterial embolization for hepatocellular carcinoma with portal vein thrombosis (1995) J Gastroenterol Hepatol, 10 (3), pp. 237-240. , 10.1111/j.1440-1746.1995.tb01086.x 1:STN:280:DyaK28%2FitlCgsw%3D%3D 7548796; Chung, J.W., Park, J.H., Han, J.K., Hepatic tumors: Predisposing factors for complications of transcatheter oily chemoembolization (1996) Radiology, 198 (1), pp. 33-40. , 1:STN:280:DyaK287itlWguw%3D%3D 8539401; White, H.D., Chew, D.P., Acute myocardial infarction (2008) Lancet, 372 (9638), pp. 570-584. , 10.1016/S0140-6736(08)61237-4 1:CAS:528:DC%2BD1cXpvFKgsLg%3D 18707987; Calvo-Romero, J.M., Fernández-Soria-Pantoja, R., Arrebola-Garcia, J.D., Ischemic heart disease associated with vincristine and doxorubicin chemotherapy (2001) Ann Pharmacother, 35 (11), pp. 1403-1405. , 10.1345/aph.10358 1:STN:280:DC%2BD3MnnslKitg%3D%3D 11724093; McCord, J.M., Oxygen-derived free radicals in postischemic tissue injury (1989) N Engl J Med, 312, pp. 159-163; Lu, W., Li, Y.H., He, X.F., Necrosis and apoptosis in hepatocellular carcinoma following low-dose versus high-dose preoperative chemoembolization (2008) Cardiovasc Interv Radiol, 31 (6), pp. 1133-1140. , 10.1007/s00270-008-9379-4; Kasugai, H., Kojima, J., Tatsuta, M., Treatment of hepatocellular carcinoma by transcatheter arterial embolization combined with intraarterial infusion of a mixture of cisplatin and ethiodized oil (1989) Gastroenterology, 97 (4), pp. 965-971. , 1:STN:280:DyaL1MznvVKktw%3D%3D 2550311

PY - 2010

Y1 - 2010

N2 - Transarterial chemoembolization has been widely used to treat unresectable hepatocellular carcinoma. Various complications have been reported, but they have not included acute myocardial infarction. Acute myocardial infarction results mainly from coronary artery occlusion by plaques that are vulnerable to rupture or from coronary spasm, embolization, or dissection of the coronary artery. It is associated with significant morbidity and mortality. We present a case report that describes a patient with hepatocellular carcinoma who underwent transarterial chemoembolization and died subsequently of acute myocardial infarction. To our knowledge, there has been no previous report of this complication induced by transarterial chemoembolization for hepatocellular carcinoma. This case illustrates the need to be aware of acute myocardial infarction when transarterial chemoembolization is planned for the treatment of hepatocellular carcinoma, especially in patients with underlying coronary artery disease. © 2009 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE).

AB - Transarterial chemoembolization has been widely used to treat unresectable hepatocellular carcinoma. Various complications have been reported, but they have not included acute myocardial infarction. Acute myocardial infarction results mainly from coronary artery occlusion by plaques that are vulnerable to rupture or from coronary spasm, embolization, or dissection of the coronary artery. It is associated with significant morbidity and mortality. We present a case report that describes a patient with hepatocellular carcinoma who underwent transarterial chemoembolization and died subsequently of acute myocardial infarction. To our knowledge, there has been no previous report of this complication induced by transarterial chemoembolization for hepatocellular carcinoma. This case illustrates the need to be aware of acute myocardial infarction when transarterial chemoembolization is planned for the treatment of hepatocellular carcinoma, especially in patients with underlying coronary artery disease. © 2009 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE).

KW - Acute myocardial infarction

KW - Hepatocellular carcinoma

KW - Transarterial chemoembolization

KW - doxorubicin

KW - gelfoam

KW - iodinated poppyseed oil

KW - pethidine

KW - abdominal pain

KW - acute heart infarction

KW - adult

KW - anorexia

KW - article

KW - case report

KW - cause of death

KW - chemoembolization

KW - cold sweat

KW - dyspnea

KW - hepatic artery

KW - human

KW - liver cell carcinoma

KW - male

KW - priority journal

KW - ST segment elevation

KW - thorax pain

KW - tumor thrombus

KW - weight reduction

KW - Arterial Occlusive Diseases

KW - Carcinoma, Hepatocellular

KW - Chemoembolization, Therapeutic

KW - Cholecystitis

KW - Coronary Disease

KW - Diabetes Mellitus, Type 2

KW - Doxorubicin

KW - Fatal Outcome

KW - Hepatic Artery

KW - Hepatitis B, Chronic

KW - Humans

KW - Iodized Oil

KW - Liver Neoplasms

KW - Male

KW - Middle Aged

KW - Myocardial Infarction

U2 - 10.1007/s00270-009-9683-7

DO - 10.1007/s00270-009-9683-7

M3 - Article

VL - 33

SP - 196

EP - 200

JO - CardioVascular and Interventional Radiology

JF - CardioVascular and Interventional Radiology

SN - 7415-5101

IS - 1

ER -

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