An on-line quantitative immunoassay system based on a quartz crystal microbalance

Shiming Lin, Chih Cheng Lu, Hsiung Fei Chien, Su Ming Hsu

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


We have established a QCM immunoassay system which allows on-line and quantitative monitoring throughout the entire detection procedure and provides information on the surface coverage and the binding ratio of antibody to antigen. Compared to conventional immunoassay systems the QCM system offers advantages of short response times, obviates the need for additive labeling reagents, and permits direct conversion of a frequency signal into mass accumulation. Copyright (C) 2000 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)121-124
Number of pages4
JournalJournal of Immunological Methods
Issue number1-2
Publication statusPublished - May 26 2000
Externally publishedYes


  • Binding ratio
  • Immunoassay
  • Polythiolation
  • Quartz crystal microbalance

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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