An efficient S-NO-polysilsesquioxane nano-platform for the co-delivery of nitric oxide and an anticancer drug

Meng Ren Wang, Shih Jiuan Chiu, Hung Chang Chou, Teh Min Hu

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Codelivery of nitric oxide (NO) and drugs based on a single nanocarrier is a promising therapeutic strategy. Here, we report a one-step nanoprecipitation method to generate nanoparticles that possess simultaneous NO-donating and doxorubicin releasing properties. S-Nitroso polysilsesquioxane acts like an avid "drug sponge" that attracts drug molecules into nanospheres.

Original languageEnglish
Pages (from-to)15649-15652
Number of pages4
JournalChemical Communications
Volume51
Issue number86
DOIs
Publication statusPublished - Sep 1 2015

Fingerprint

Nitric oxide
Nitric Oxide
Nanospheres
Pharmaceutical Preparations
Nanoparticles
Doxorubicin
Molecules
polysilsesquioxane

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Materials Chemistry
  • Metals and Alloys

Cite this

An efficient S-NO-polysilsesquioxane nano-platform for the co-delivery of nitric oxide and an anticancer drug. / Wang, Meng Ren; Chiu, Shih Jiuan; Chou, Hung Chang; Hu, Teh Min.

In: Chemical Communications, Vol. 51, No. 86, 01.09.2015, p. 15649-15652.

Research output: Contribution to journalArticle

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