An efficient S-NO-polysilsesquioxane nano-platform for the co-delivery of nitric oxide and an anticancer drug

Meng Ren Wang, Shih Jiuan Chiu, Hung Chang Chou, Teh Min Hu

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Codelivery of nitric oxide (NO) and drugs based on a single nanocarrier is a promising therapeutic strategy. Here, we report a one-step nanoprecipitation method to generate nanoparticles that possess simultaneous NO-donating and doxorubicin releasing properties. S-Nitroso polysilsesquioxane acts like an avid "drug sponge" that attracts drug molecules into nanospheres.

Original languageEnglish
Pages (from-to)15649-15652
Number of pages4
JournalChemical Communications
Volume51
Issue number86
DOIs
Publication statusPublished - Sep 1 2015

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ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Materials Chemistry
  • Metals and Alloys

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