Ambulatory pulse pressure as a novel predictor for long-term prognosis in essential hypertensive patients

Y. T. Kao, C. C. Huang, H. B. Leu, T. C. Wu, P. H. Huang, S. J. Lin, J. W. Chen

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The prognostic value of ambulatory blood pressure (BP) monitoring for long-term prognosis varies in recent studies. The study aimed to investigate the role of ambulatory BP parameters in mortality and cardiovascular (CV) events in hypertensive patients. A series of 412 participants (59.34.0 years) who received ambulatory BP monitoring for their fluctuated BP, either untreated or treated since 1995, were enroled. The mortality and CV events were obtained by follow-up and linked to the National Death Registry in Taiwan. There were 233 untreated and 179 treated patients. The latter were older with more comorbidity when compared with the former. After follow-up for 8.51.7 years, both ambulatory systolic BP and pulse pressure (PP) could predict all-cause mortality, non-CV mortality, CV disease and stroke after adjusting for baseline covariates. However, only ambulatory PP could predict CV mortality and coronary heart disease. Ambulatory PP is better than ambulatory systolic BP, particularly in prediction of all-cause mortality. There was no predictive value of office BP in any outcome. In conclusion, ambulatory PP is a good predictor for long-term outcomes in hypertensive patients. The parameters of ambulatory rather than office BP could be applied for risk stratification either before or under antihypertensive treatment.

Original languageEnglish
Pages (from-to)444-450
Number of pages7
JournalJournal of Human Hypertension
Volume25
Issue number7
DOIs
Publication statusPublished - Jul 2011
Externally publishedYes

Fingerprint

Blood Pressure
Mortality
Ambulatory Blood Pressure Monitoring
Taiwan
Antihypertensive Agents
Coronary Disease
Registries
Comorbidity
Cardiovascular Diseases
Myocardial Infarction

Keywords

  • ambulatory blood pressure monitoring
  • cardiovascular events
  • mortality
  • pulse pressure

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Ambulatory pulse pressure as a novel predictor for long-term prognosis in essential hypertensive patients. / Kao, Y. T.; Huang, C. C.; Leu, H. B.; Wu, T. C.; Huang, P. H.; Lin, S. J.; Chen, J. W.

In: Journal of Human Hypertension, Vol. 25, No. 7, 07.2011, p. 444-450.

Research output: Contribution to journalArticle

Kao, Y. T. ; Huang, C. C. ; Leu, H. B. ; Wu, T. C. ; Huang, P. H. ; Lin, S. J. ; Chen, J. W. / Ambulatory pulse pressure as a novel predictor for long-term prognosis in essential hypertensive patients. In: Journal of Human Hypertension. 2011 ; Vol. 25, No. 7. pp. 444-450.
@article{8388061aa0a04529b79865d543eebdc6,
title = "Ambulatory pulse pressure as a novel predictor for long-term prognosis in essential hypertensive patients",
abstract = "The prognostic value of ambulatory blood pressure (BP) monitoring for long-term prognosis varies in recent studies. The study aimed to investigate the role of ambulatory BP parameters in mortality and cardiovascular (CV) events in hypertensive patients. A series of 412 participants (59.34.0 years) who received ambulatory BP monitoring for their fluctuated BP, either untreated or treated since 1995, were enroled. The mortality and CV events were obtained by follow-up and linked to the National Death Registry in Taiwan. There were 233 untreated and 179 treated patients. The latter were older with more comorbidity when compared with the former. After follow-up for 8.51.7 years, both ambulatory systolic BP and pulse pressure (PP) could predict all-cause mortality, non-CV mortality, CV disease and stroke after adjusting for baseline covariates. However, only ambulatory PP could predict CV mortality and coronary heart disease. Ambulatory PP is better than ambulatory systolic BP, particularly in prediction of all-cause mortality. There was no predictive value of office BP in any outcome. In conclusion, ambulatory PP is a good predictor for long-term outcomes in hypertensive patients. The parameters of ambulatory rather than office BP could be applied for risk stratification either before or under antihypertensive treatment.",
keywords = "ambulatory blood pressure monitoring, cardiovascular events, mortality, pulse pressure",
author = "Kao, {Y. T.} and Huang, {C. C.} and Leu, {H. B.} and Wu, {T. C.} and Huang, {P. H.} and Lin, {S. J.} and Chen, {J. W.}",
year = "2011",
month = "7",
doi = "10.1038/jhh.2010.80",
language = "English",
volume = "25",
pages = "444--450",
journal = "Journal of Human Hypertension",
issn = "0950-9240",
publisher = "Nature Publishing Group",
number = "7",

}

TY - JOUR

T1 - Ambulatory pulse pressure as a novel predictor for long-term prognosis in essential hypertensive patients

AU - Kao, Y. T.

AU - Huang, C. C.

AU - Leu, H. B.

AU - Wu, T. C.

AU - Huang, P. H.

AU - Lin, S. J.

AU - Chen, J. W.

PY - 2011/7

Y1 - 2011/7

N2 - The prognostic value of ambulatory blood pressure (BP) monitoring for long-term prognosis varies in recent studies. The study aimed to investigate the role of ambulatory BP parameters in mortality and cardiovascular (CV) events in hypertensive patients. A series of 412 participants (59.34.0 years) who received ambulatory BP monitoring for their fluctuated BP, either untreated or treated since 1995, were enroled. The mortality and CV events were obtained by follow-up and linked to the National Death Registry in Taiwan. There were 233 untreated and 179 treated patients. The latter were older with more comorbidity when compared with the former. After follow-up for 8.51.7 years, both ambulatory systolic BP and pulse pressure (PP) could predict all-cause mortality, non-CV mortality, CV disease and stroke after adjusting for baseline covariates. However, only ambulatory PP could predict CV mortality and coronary heart disease. Ambulatory PP is better than ambulatory systolic BP, particularly in prediction of all-cause mortality. There was no predictive value of office BP in any outcome. In conclusion, ambulatory PP is a good predictor for long-term outcomes in hypertensive patients. The parameters of ambulatory rather than office BP could be applied for risk stratification either before or under antihypertensive treatment.

AB - The prognostic value of ambulatory blood pressure (BP) monitoring for long-term prognosis varies in recent studies. The study aimed to investigate the role of ambulatory BP parameters in mortality and cardiovascular (CV) events in hypertensive patients. A series of 412 participants (59.34.0 years) who received ambulatory BP monitoring for their fluctuated BP, either untreated or treated since 1995, were enroled. The mortality and CV events were obtained by follow-up and linked to the National Death Registry in Taiwan. There were 233 untreated and 179 treated patients. The latter were older with more comorbidity when compared with the former. After follow-up for 8.51.7 years, both ambulatory systolic BP and pulse pressure (PP) could predict all-cause mortality, non-CV mortality, CV disease and stroke after adjusting for baseline covariates. However, only ambulatory PP could predict CV mortality and coronary heart disease. Ambulatory PP is better than ambulatory systolic BP, particularly in prediction of all-cause mortality. There was no predictive value of office BP in any outcome. In conclusion, ambulatory PP is a good predictor for long-term outcomes in hypertensive patients. The parameters of ambulatory rather than office BP could be applied for risk stratification either before or under antihypertensive treatment.

KW - ambulatory blood pressure monitoring

KW - cardiovascular events

KW - mortality

KW - pulse pressure

UR - http://www.scopus.com/inward/record.url?scp=79959317768&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79959317768&partnerID=8YFLogxK

U2 - 10.1038/jhh.2010.80

DO - 10.1038/jhh.2010.80

M3 - Article

VL - 25

SP - 444

EP - 450

JO - Journal of Human Hypertension

JF - Journal of Human Hypertension

SN - 0950-9240

IS - 7

ER -