Allergic rhinitis is associated with periodontitis: A population-based study

Shih Han Hung, Ming Chieh Tsai, Herng Ching Lin, Shiu Dong Chung

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background: Little is known regarding associations of periodontitis with diseases of the nose, one of the structures adjacent to the mouth. This study aims to explore the association between periodontitis and previous allergic rhinitis (AR) using amatched patient-control study design from a population-based dataset in Taiwan. Methods: Data were sourced from the Longitudinal Health Insurance Database 2000 for 71,182 patients with chronic periodontitis (CP) and 71,182 controls without periodontitis. Generalized linear mixed-model analyses were used to calculate odds ratios (ORs) and corresponding 95% confidence intervals (CIs) for previous AR diagnosis in patients and controls. Results: Significant difference was found in prevalence of prior AR for patients and controls (28.4% versus 24.2%; P <0.001). Generalized linear mixed model suggested that the OR of previous AR for patients was 1.24 (95% CI: 1.22 to 1.27; P <0.001) compared with controls. Adjustments were made for: 1) monthly income; 2) urbanization level; 3) diabetes mellitus; 4) hypertension; 5) coronary heart disease; 6) hyperlipidemia; 7) alcohol abuse; 8) tobacco use disorder; and 9) random effect of geographic region. After adjusting, OR of previous AR diagnosis among patients was 1.21 (95% CI: 1.18 to 1.23; P <0.001) compared with controls. Conclusions: An association between periodontitis and prior AR is demonstrated. It is recommended that physicians be more alert for potential risk of subsequent development of CP in patients with AR.

Original languageEnglish
Pages (from-to)749-755
Number of pages7
JournalJournal of Periodontology
Volume87
Issue number7
DOIs
Publication statusPublished - Jul 1 2016

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Periodontitis
Population
Chronic Periodontitis
Odds Ratio
Confidence Intervals
Linear Models
Nose Diseases
Social Adjustment
Tobacco Use Disorder
Urbanization
Health Insurance
Allergic Rhinitis
Hyperlipidemias
Taiwan
Alcoholism
Coronary Disease
Mouth
Diabetes Mellitus
Databases
Hypertension

Keywords

  • Allergic.
  • Epidemiology
  • Periodontitis
  • Rhinitis

ASJC Scopus subject areas

  • Periodontics

Cite this

Allergic rhinitis is associated with periodontitis : A population-based study. / Hung, Shih Han; Tsai, Ming Chieh; Lin, Herng Ching; Chung, Shiu Dong.

In: Journal of Periodontology, Vol. 87, No. 7, 01.07.2016, p. 749-755.

Research output: Contribution to journalArticle

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abstract = "Background: Little is known regarding associations of periodontitis with diseases of the nose, one of the structures adjacent to the mouth. This study aims to explore the association between periodontitis and previous allergic rhinitis (AR) using amatched patient-control study design from a population-based dataset in Taiwan. Methods: Data were sourced from the Longitudinal Health Insurance Database 2000 for 71,182 patients with chronic periodontitis (CP) and 71,182 controls without periodontitis. Generalized linear mixed-model analyses were used to calculate odds ratios (ORs) and corresponding 95{\%} confidence intervals (CIs) for previous AR diagnosis in patients and controls. Results: Significant difference was found in prevalence of prior AR for patients and controls (28.4{\%} versus 24.2{\%}; P <0.001). Generalized linear mixed model suggested that the OR of previous AR for patients was 1.24 (95{\%} CI: 1.22 to 1.27; P <0.001) compared with controls. Adjustments were made for: 1) monthly income; 2) urbanization level; 3) diabetes mellitus; 4) hypertension; 5) coronary heart disease; 6) hyperlipidemia; 7) alcohol abuse; 8) tobacco use disorder; and 9) random effect of geographic region. After adjusting, OR of previous AR diagnosis among patients was 1.21 (95{\%} CI: 1.18 to 1.23; P <0.001) compared with controls. Conclusions: An association between periodontitis and prior AR is demonstrated. It is recommended that physicians be more alert for potential risk of subsequent development of CP in patients with AR.",
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