Allergic rhinitis is associated with open-angle glaucoma: A population-based case - Control study

Shiu Dong Chung, Herng-Ching Lin, Shih-Han Hung

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background: Despite many reports linking allergic rhinitis (AR) to problems of the eye, the relationship between AR and open-angle glaucoma (OAG) has not been studied. The purpose of this epidemiology study was to provide an estimation of the association of OAG with AR by using a population-based data set in Taiwan. Methods: We retrieved our study sample for this case - control study from the Longitudinal Health Insurance Database 2000. We extracted 7063 subjects with OAG as cases and 21,189 matched controls (three controls per case). We used conditional logistic regression analyses to calculate the odds ratio (OR) and corresponding 95% confidence interval (CI) to describe the association between OAG and having previously been diagnosed with AR. Results: A chi-squared test showed that there was a significant difference in the prevalence of prior AR between cases and controls (28.8% versus 22.3%; p <0.001). A conditional logistic regression analysis suggested that the OR of having previously been diagnosed with AR for cases was 1.40 (95% CI, 1.31~1.48; p <0.001) compared with controls after adjusting for monthly income, geographic region, urbanization level, hypertension, diabetes, asthma, coronary heart disease, hyperlipidemia, and hypothyroidism. It also revealed that OAG was consistently and significantly associated with prior AR across all age groups. In particular, subjects aged 50~59 years had the highest OR for prior AR among cases compared with controls (OR, 1.77; 95% CI, 1.53~2.06; p <0.001). Conclusion: This outcome research found that there was an association between AR and OAG.

Original languageEnglish
Pages (from-to)e148-e151
JournalAmerican Journal of Rhinology and Allergy
Volume28
Issue number4
DOIs
Publication statusPublished - 2014

Fingerprint

Open Angle Glaucoma
Case-Control Studies
Population
Odds Ratio
Confidence Intervals
Logistic Models
Regression Analysis
Allergic Rhinitis
Urbanization
Health Insurance
Hypothyroidism
Hyperlipidemias
Taiwan
Coronary Disease
Epidemiology
Asthma
Age Groups
Outcome Assessment (Health Care)
Databases
Hypertension

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Immunology and Allergy
  • Medicine(all)

Cite this

@article{50211cc59c9846e996d633852debac4d,
title = "Allergic rhinitis is associated with open-angle glaucoma: A population-based case - Control study",
abstract = "Background: Despite many reports linking allergic rhinitis (AR) to problems of the eye, the relationship between AR and open-angle glaucoma (OAG) has not been studied. The purpose of this epidemiology study was to provide an estimation of the association of OAG with AR by using a population-based data set in Taiwan. Methods: We retrieved our study sample for this case - control study from the Longitudinal Health Insurance Database 2000. We extracted 7063 subjects with OAG as cases and 21,189 matched controls (three controls per case). We used conditional logistic regression analyses to calculate the odds ratio (OR) and corresponding 95{\%} confidence interval (CI) to describe the association between OAG and having previously been diagnosed with AR. Results: A chi-squared test showed that there was a significant difference in the prevalence of prior AR between cases and controls (28.8{\%} versus 22.3{\%}; p <0.001). A conditional logistic regression analysis suggested that the OR of having previously been diagnosed with AR for cases was 1.40 (95{\%} CI, 1.31~1.48; p <0.001) compared with controls after adjusting for monthly income, geographic region, urbanization level, hypertension, diabetes, asthma, coronary heart disease, hyperlipidemia, and hypothyroidism. It also revealed that OAG was consistently and significantly associated with prior AR across all age groups. In particular, subjects aged 50~59 years had the highest OR for prior AR among cases compared with controls (OR, 1.77; 95{\%} CI, 1.53~2.06; p <0.001). Conclusion: This outcome research found that there was an association between AR and OAG.",
author = "Chung, {Shiu Dong} and Herng-Ching Lin and Shih-Han Hung",
year = "2014",
doi = "10.2500/ajra.2014.28.4060",
language = "English",
volume = "28",
pages = "e148--e151",
journal = "American Journal of Rhinology and Allergy",
issn = "1945-8924",
publisher = "OceanSide Publications Inc.",
number = "4",

}

TY - JOUR

T1 - Allergic rhinitis is associated with open-angle glaucoma

T2 - A population-based case - Control study

AU - Chung, Shiu Dong

AU - Lin, Herng-Ching

AU - Hung, Shih-Han

PY - 2014

Y1 - 2014

N2 - Background: Despite many reports linking allergic rhinitis (AR) to problems of the eye, the relationship between AR and open-angle glaucoma (OAG) has not been studied. The purpose of this epidemiology study was to provide an estimation of the association of OAG with AR by using a population-based data set in Taiwan. Methods: We retrieved our study sample for this case - control study from the Longitudinal Health Insurance Database 2000. We extracted 7063 subjects with OAG as cases and 21,189 matched controls (three controls per case). We used conditional logistic regression analyses to calculate the odds ratio (OR) and corresponding 95% confidence interval (CI) to describe the association between OAG and having previously been diagnosed with AR. Results: A chi-squared test showed that there was a significant difference in the prevalence of prior AR between cases and controls (28.8% versus 22.3%; p <0.001). A conditional logistic regression analysis suggested that the OR of having previously been diagnosed with AR for cases was 1.40 (95% CI, 1.31~1.48; p <0.001) compared with controls after adjusting for monthly income, geographic region, urbanization level, hypertension, diabetes, asthma, coronary heart disease, hyperlipidemia, and hypothyroidism. It also revealed that OAG was consistently and significantly associated with prior AR across all age groups. In particular, subjects aged 50~59 years had the highest OR for prior AR among cases compared with controls (OR, 1.77; 95% CI, 1.53~2.06; p <0.001). Conclusion: This outcome research found that there was an association between AR and OAG.

AB - Background: Despite many reports linking allergic rhinitis (AR) to problems of the eye, the relationship between AR and open-angle glaucoma (OAG) has not been studied. The purpose of this epidemiology study was to provide an estimation of the association of OAG with AR by using a population-based data set in Taiwan. Methods: We retrieved our study sample for this case - control study from the Longitudinal Health Insurance Database 2000. We extracted 7063 subjects with OAG as cases and 21,189 matched controls (three controls per case). We used conditional logistic regression analyses to calculate the odds ratio (OR) and corresponding 95% confidence interval (CI) to describe the association between OAG and having previously been diagnosed with AR. Results: A chi-squared test showed that there was a significant difference in the prevalence of prior AR between cases and controls (28.8% versus 22.3%; p <0.001). A conditional logistic regression analysis suggested that the OR of having previously been diagnosed with AR for cases was 1.40 (95% CI, 1.31~1.48; p <0.001) compared with controls after adjusting for monthly income, geographic region, urbanization level, hypertension, diabetes, asthma, coronary heart disease, hyperlipidemia, and hypothyroidism. It also revealed that OAG was consistently and significantly associated with prior AR across all age groups. In particular, subjects aged 50~59 years had the highest OR for prior AR among cases compared with controls (OR, 1.77; 95% CI, 1.53~2.06; p <0.001). Conclusion: This outcome research found that there was an association between AR and OAG.

UR - http://www.scopus.com/inward/record.url?scp=84905126545&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84905126545&partnerID=8YFLogxK

U2 - 10.2500/ajra.2014.28.4060

DO - 10.2500/ajra.2014.28.4060

M3 - Article

C2 - 25197907

AN - SCOPUS:84905126545

VL - 28

SP - e148-e151

JO - American Journal of Rhinology and Allergy

JF - American Journal of Rhinology and Allergy

SN - 1945-8924

IS - 4

ER -