Abstract
Background: Variability in weight loss has been observed from morbidly obese patients receiving bariatric operations. Genetic effects may play a crucial role in this variability. Methods: 304 morbidly obese patients (BMI ≥39) were recruited, 77 receiving laparoscopic adjustable gastric banding (LAGB) and 227 laparoscopic mini-gastric bypass (LMGB), and 304 matched non-obese controls (BMI ≤24). Initially, all subjects were genotyped for 4 SNPs (single nucleotide polymorphisms) on UCP2 gene in a case-control study. The SNPs significantly associated with morbid obesity (P
| Original language | English |
|---|---|
| Pages (from-to) | 926-933 |
| Number of pages | 8 |
| Journal | Obesity Surgery |
| Volume | 17 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 2007 |
Keywords
- Gastric banding
- Gene
- Mini-gastric bypass
- Morbid obesity
- Obesity surgery
- Predictor
- UCP2
- Weight loss
ASJC Scopus subject areas
- Surgery
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Chen, H. H., Lee, W. J., Wang, W., Huang, M. T., Lee, Y. C., & Pan, W. H. (2007). Ala55Val polymorphism on UCP2 gene predicts greater weight loss in morbidly obese patients undergoing gastric banding. Obesity Surgery, 17(7), 926-933. https://doi.org/10.1007/s11695-007-9171-6