Airway Changes after Cleft Orthognathic Surgery Evaluated by Three-Dimensional Computed Tomography and Overnight Polysomnographic Study

Chun Shin Chang, Christopher Glenn Wallace, Yen Chang Hsiao, Yuh Jia Hsieh, Yi Chin Wang, Ning Hung Chen, Yu Fang Liao, Eric Jen Wein Liou, Philip Kuo Ting Chen, Jyh Ping Chen, Yu Ray Chen

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Cleft lip and palate is the most common congenital craniofacial anomaly. Up to 60% of these patients will benefit from cleft orthognathic surgery, which consists primarily of maxillary advancement and mandibular setback to address midface retrusion and relative mandibular protrusion, respectively. It is believed that maxillary advancement can enlarge the airway whilst mandibular setback can reduce the airway, but this has not previously been quantified for cleft patients undergoing orthognathic surgery. This unique longitudinal prospective study of 18 patients was conducted between April 2013 and July 2016. No significant changes occurred by six months postoperatively in body mass index, apnoea-hypopnoea index or lowest oxygen saturation (LSAT). There was a mean increase of 0.73 cm3 in velopharyngeal volume, a mean decrease of 0.79 cm3 in oropharyngeal volume, an improvement in snoring index, and no statistically significant change in hypopharyngeal volume. In conclusion, cleft orthognathic surgery that produced anterior advancement of the maxilla, setback of the mandible and clockwise rotation of the maxillo-mandibular complex resulted in increased velopharyngeal, decreased oropharyngeal and unchanged hypopharyngeal airways, and improved snoring, but did not significantly alter objective sleep-related breathing function.

Original languageEnglish
Article number12260
JournalScientific Reports
Volume7
Issue number1
DOIs
Publication statusPublished - Dec 1 2017
Externally publishedYes

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Orthognathic Surgery
Snoring
Tomography
Mandibular Advancement
Retrognathia
Cleft Lip
Maxilla
Cleft Palate
Apnea
Mandible
Longitudinal Studies
Sleep
Respiration
Body Mass Index
Prospective Studies
Oxygen

ASJC Scopus subject areas

  • General

Cite this

Airway Changes after Cleft Orthognathic Surgery Evaluated by Three-Dimensional Computed Tomography and Overnight Polysomnographic Study. / Chang, Chun Shin; Wallace, Christopher Glenn; Hsiao, Yen Chang; Hsieh, Yuh Jia; Wang, Yi Chin; Chen, Ning Hung; Liao, Yu Fang; Liou, Eric Jen Wein; Chen, Philip Kuo Ting; Chen, Jyh Ping; Chen, Yu Ray.

In: Scientific Reports, Vol. 7, No. 1, 12260, 01.12.2017.

Research output: Contribution to journalArticle

Chang, CS, Wallace, CG, Hsiao, YC, Hsieh, YJ, Wang, YC, Chen, NH, Liao, YF, Liou, EJW, Chen, PKT, Chen, JP & Chen, YR 2017, 'Airway Changes after Cleft Orthognathic Surgery Evaluated by Three-Dimensional Computed Tomography and Overnight Polysomnographic Study', Scientific Reports, vol. 7, no. 1, 12260. https://doi.org/10.1038/s41598-017-12251-4
Chang, Chun Shin ; Wallace, Christopher Glenn ; Hsiao, Yen Chang ; Hsieh, Yuh Jia ; Wang, Yi Chin ; Chen, Ning Hung ; Liao, Yu Fang ; Liou, Eric Jen Wein ; Chen, Philip Kuo Ting ; Chen, Jyh Ping ; Chen, Yu Ray. / Airway Changes after Cleft Orthognathic Surgery Evaluated by Three-Dimensional Computed Tomography and Overnight Polysomnographic Study. In: Scientific Reports. 2017 ; Vol. 7, No. 1.
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