Aging effects on the activation of the auditory cortex during binaural speech listening in white noise

An fMRI study

Juen Haur Hwang, Chia Wei Li, Chang Wei Wu, Jyh Horng Chen, Tien Chen Liu

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

The functional significance of age-related pathology of the auditory cortex is not well established. The purpose of this study was to elucidate the activation pattern of the auditory cortex in aged subjects in response to speech signals. Functional magnetic resonance imaging was performed on 12 elderly subjects with normal hearing acuity during selective listening with both ears to speech sounds in quiet and in white noise. Twelve young, normal-hearing subjects served as controls. Our results showed that activation of the auditory cortex during selective listening to speech decreased in elderly subjects compared to young subjects, especially in noise. Reduced activation occurred in the anterior and posterior regions of the bilateral superior temporal gyrus (STG), but mainly in the posterior part of the left STG. In addition, background noise had a greater masking effect on speech perception in the elderly subjects than in the young ones. These findings suggest that early functional changes associated with central presbycusis occur mainly in the posterior part of the left STG.

Original languageEnglish
Pages (from-to)285-294
Number of pages10
JournalAudiology and Neurotology
Volume12
Issue number5
DOIs
Publication statusPublished - Aug 1 2007
Externally publishedYes

Fingerprint

Auditory Cortex
Magnetic Resonance Imaging
Hearing
Noise
Presbycusis
Speech Perception
Phonetics
Temporal Lobe
Ear
Pathology
Wernicke Area

Keywords

  • Aging
  • Auditory cortex
  • Functional magnetic resonance imaging
  • Speech perception, noise

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Physiology
  • Sensory Systems
  • Speech and Hearing

Cite this

Aging effects on the activation of the auditory cortex during binaural speech listening in white noise : An fMRI study. / Hwang, Juen Haur; Li, Chia Wei; Wu, Chang Wei; Chen, Jyh Horng; Liu, Tien Chen.

In: Audiology and Neurotology, Vol. 12, No. 5, 01.08.2007, p. 285-294.

Research output: Contribution to journalArticle

Hwang, Juen Haur ; Li, Chia Wei ; Wu, Chang Wei ; Chen, Jyh Horng ; Liu, Tien Chen. / Aging effects on the activation of the auditory cortex during binaural speech listening in white noise : An fMRI study. In: Audiology and Neurotology. 2007 ; Vol. 12, No. 5. pp. 285-294.
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