Age-specific and sex-specific differences in diagnostic accuracy of high-resolution ultrasonography for acute appendicitis

Chun Jung Juan, Chun Jen Hsueh, Chih Wang Huang, Chang Hsien Liou, Shy Chyi Chin, Ming Yung Lee, Yen Liang Kuo, Ching Jiunn Wu, Chih Yung Yu, Cheng Yu Chen, Ting Ywan Chou

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Abstract

Objective: To evaluate the diagnostic capability of high-resolution ultrasonography (HRUS) for clinically suspected acute appendicitis in patients of different sex and age presenting with acute right lower quadrant pain at the Emergency Department of Tri-Service General Hospital, Taipei, Taiwan. Materials and methods: The study included 734 consecutive patients (366 males and 368 females) in whom acute appendicitis was clinically suspected and evaluated using HRUS between January 1997 and November 1999. Patients were classified into two groups by sex, and further classified into four age groups (I = 0-17 yr; II = 18-45 yr; III = 46-60 yr; IV = > 60 yr) for categorical analysis. We retrospectively reviewed and compared the patients' HRUS images with their operative findings and histologic results to evaluate the overall age-specific and sex-specific diagnostic ability of HRUS for acute appendicitis. The chi-square test was used for categorical data analysis. Comparative analysis of our data with previously published data on the correlation between the prevalence of acute appendicitis and sonographic diagnosis of acute appendicitis was performed using linear regression. Results: The overall accuracy, sensitivity, specificity, positive and negative predictive rates were 89%, 87%, 90%, 89% and 88%, respectively. Age-specific analysis revealed a statistically significant difference in diagnostic accuracy between age groups II and III among women (85% vs 96%, respectively; p <0.05). Sex-specific analysis of age group II showed higher sensitivity (90% vs 77%; p <0.05) and positive predictive values (89% vs 77%; p <0.05) in women than in men, respectively. In age group III, the accuracy of HRUS was higher in men than in women (96% vs 84%, respectively; p <0.05). The negative predictive value and overall diagnostic accuracy were negatively correlated to the prevalence of acute appendicitis. Conclusion: The value of HRUS for the diagnosis of acute appendicitis varied among different age and sex groups. The prevalence of acute appendicitis was negatively correlated with the negative predictive value and overall diagnostic accuracy of HRUS for acute appendicitis.

Original languageEnglish
Pages (from-to)10-19
Number of pages10
JournalJournal of Medical Ultrasound
Volume10
Issue number1
Publication statusPublished - 2002
Externally publishedYes

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Appendicitis
Sex Characteristics
Ultrasonography
Age Groups
Aptitude
Chi-Square Distribution
Taiwan
General Hospitals
Hospital Emergency Service
Linear Models
Sensitivity and Specificity
Pain

Keywords

  • Acute appendicitis
  • High-resolution ultrasonography (HRUS)

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Juan, C. J., Hsueh, C. J., Huang, C. W., Liou, C. H., Chin, S. C., Lee, M. Y., ... Chou, T. Y. (2002). Age-specific and sex-specific differences in diagnostic accuracy of high-resolution ultrasonography for acute appendicitis. Journal of Medical Ultrasound, 10(1), 10-19.

Age-specific and sex-specific differences in diagnostic accuracy of high-resolution ultrasonography for acute appendicitis. / Juan, Chun Jung; Hsueh, Chun Jen; Huang, Chih Wang; Liou, Chang Hsien; Chin, Shy Chyi; Lee, Ming Yung; Kuo, Yen Liang; Wu, Ching Jiunn; Yu, Chih Yung; Chen, Cheng Yu; Chou, Ting Ywan.

In: Journal of Medical Ultrasound, Vol. 10, No. 1, 2002, p. 10-19.

Research output: Contribution to journalArticle

Juan, CJ, Hsueh, CJ, Huang, CW, Liou, CH, Chin, SC, Lee, MY, Kuo, YL, Wu, CJ, Yu, CY, Chen, CY & Chou, TY 2002, 'Age-specific and sex-specific differences in diagnostic accuracy of high-resolution ultrasonography for acute appendicitis', Journal of Medical Ultrasound, vol. 10, no. 1, pp. 10-19.
Juan, Chun Jung ; Hsueh, Chun Jen ; Huang, Chih Wang ; Liou, Chang Hsien ; Chin, Shy Chyi ; Lee, Ming Yung ; Kuo, Yen Liang ; Wu, Ching Jiunn ; Yu, Chih Yung ; Chen, Cheng Yu ; Chou, Ting Ywan. / Age-specific and sex-specific differences in diagnostic accuracy of high-resolution ultrasonography for acute appendicitis. In: Journal of Medical Ultrasound. 2002 ; Vol. 10, No. 1. pp. 10-19.
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T1 - Age-specific and sex-specific differences in diagnostic accuracy of high-resolution ultrasonography for acute appendicitis

AU - Juan, Chun Jung

AU - Hsueh, Chun Jen

AU - Huang, Chih Wang

AU - Liou, Chang Hsien

AU - Chin, Shy Chyi

AU - Lee, Ming Yung

AU - Kuo, Yen Liang

AU - Wu, Ching Jiunn

AU - Yu, Chih Yung

AU - Chen, Cheng Yu

AU - Chou, Ting Ywan

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N2 - Objective: To evaluate the diagnostic capability of high-resolution ultrasonography (HRUS) for clinically suspected acute appendicitis in patients of different sex and age presenting with acute right lower quadrant pain at the Emergency Department of Tri-Service General Hospital, Taipei, Taiwan. Materials and methods: The study included 734 consecutive patients (366 males and 368 females) in whom acute appendicitis was clinically suspected and evaluated using HRUS between January 1997 and November 1999. Patients were classified into two groups by sex, and further classified into four age groups (I = 0-17 yr; II = 18-45 yr; III = 46-60 yr; IV = > 60 yr) for categorical analysis. We retrospectively reviewed and compared the patients' HRUS images with their operative findings and histologic results to evaluate the overall age-specific and sex-specific diagnostic ability of HRUS for acute appendicitis. The chi-square test was used for categorical data analysis. Comparative analysis of our data with previously published data on the correlation between the prevalence of acute appendicitis and sonographic diagnosis of acute appendicitis was performed using linear regression. Results: The overall accuracy, sensitivity, specificity, positive and negative predictive rates were 89%, 87%, 90%, 89% and 88%, respectively. Age-specific analysis revealed a statistically significant difference in diagnostic accuracy between age groups II and III among women (85% vs 96%, respectively; p <0.05). Sex-specific analysis of age group II showed higher sensitivity (90% vs 77%; p <0.05) and positive predictive values (89% vs 77%; p <0.05) in women than in men, respectively. In age group III, the accuracy of HRUS was higher in men than in women (96% vs 84%, respectively; p <0.05). The negative predictive value and overall diagnostic accuracy were negatively correlated to the prevalence of acute appendicitis. Conclusion: The value of HRUS for the diagnosis of acute appendicitis varied among different age and sex groups. The prevalence of acute appendicitis was negatively correlated with the negative predictive value and overall diagnostic accuracy of HRUS for acute appendicitis.

AB - Objective: To evaluate the diagnostic capability of high-resolution ultrasonography (HRUS) for clinically suspected acute appendicitis in patients of different sex and age presenting with acute right lower quadrant pain at the Emergency Department of Tri-Service General Hospital, Taipei, Taiwan. Materials and methods: The study included 734 consecutive patients (366 males and 368 females) in whom acute appendicitis was clinically suspected and evaluated using HRUS between January 1997 and November 1999. Patients were classified into two groups by sex, and further classified into four age groups (I = 0-17 yr; II = 18-45 yr; III = 46-60 yr; IV = > 60 yr) for categorical analysis. We retrospectively reviewed and compared the patients' HRUS images with their operative findings and histologic results to evaluate the overall age-specific and sex-specific diagnostic ability of HRUS for acute appendicitis. The chi-square test was used for categorical data analysis. Comparative analysis of our data with previously published data on the correlation between the prevalence of acute appendicitis and sonographic diagnosis of acute appendicitis was performed using linear regression. Results: The overall accuracy, sensitivity, specificity, positive and negative predictive rates were 89%, 87%, 90%, 89% and 88%, respectively. Age-specific analysis revealed a statistically significant difference in diagnostic accuracy between age groups II and III among women (85% vs 96%, respectively; p <0.05). Sex-specific analysis of age group II showed higher sensitivity (90% vs 77%; p <0.05) and positive predictive values (89% vs 77%; p <0.05) in women than in men, respectively. In age group III, the accuracy of HRUS was higher in men than in women (96% vs 84%, respectively; p <0.05). The negative predictive value and overall diagnostic accuracy were negatively correlated to the prevalence of acute appendicitis. Conclusion: The value of HRUS for the diagnosis of acute appendicitis varied among different age and sex groups. The prevalence of acute appendicitis was negatively correlated with the negative predictive value and overall diagnostic accuracy of HRUS for acute appendicitis.

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