Age-dependent vulnerability of cyclosporine-associated encephalopathy in children

Li Wen Chen, Jiann Shiuh Chen, Yi Fang Tu, Shan Tair Wang, Lan Wan Wang, Yi Shan Tsai, Chao Ching Huang

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Introduction Cyclosporine (CsA) is an immunosuppressant known for its neurotoxicity, which presents with acute encephalopathy and seizures in the most severe form. However, whether there is age-related neurological susceptibility in pediatric population is poorly defined. The study aims to examine the vulnerability of CsA neurotoxicity among different age groups of pediatric patients in terms of occurrence rate, acute presentations, long-term outcomes, and neuroimaging findings. Methods Pediatric patients (age

Original languageEnglish
Pages (from-to)464-471
Number of pages8
JournalEuropean Journal of Paediatric Neurology
Volume19
Issue number4
DOIs
Publication statusPublished - Jul 1 2015

Fingerprint

Brain Diseases
Cyclosporine
Pediatrics
Immunosuppressive Agents
Neuroimaging
Seizures
Age Groups
Population

Keywords

  • Age factors
  • Child
  • Cyclosporine
  • Neurotoxicity syndromes
  • Seizures
  • Status epilepticus

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health

Cite this

Age-dependent vulnerability of cyclosporine-associated encephalopathy in children. / Chen, Li Wen; Chen, Jiann Shiuh; Tu, Yi Fang; Wang, Shan Tair; Wang, Lan Wan; Tsai, Yi Shan; Huang, Chao Ching.

In: European Journal of Paediatric Neurology, Vol. 19, No. 4, 01.07.2015, p. 464-471.

Research output: Contribution to journalArticle

Chen, Li Wen ; Chen, Jiann Shiuh ; Tu, Yi Fang ; Wang, Shan Tair ; Wang, Lan Wan ; Tsai, Yi Shan ; Huang, Chao Ching. / Age-dependent vulnerability of cyclosporine-associated encephalopathy in children. In: European Journal of Paediatric Neurology. 2015 ; Vol. 19, No. 4. pp. 464-471.
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