Abstract
Introduction Cyclosporine (CsA) is an immunosuppressant known for its neurotoxicity, which presents with acute encephalopathy and seizures in the most severe form. However, whether there is age-related neurological susceptibility in pediatric population is poorly defined. The study aims to examine the vulnerability of CsA neurotoxicity among different age groups of pediatric patients in terms of occurrence rate, acute presentations, long-term outcomes, and neuroimaging findings. Methods Pediatric patients (age
Original language | English |
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Pages (from-to) | 464-471 |
Number of pages | 8 |
Journal | European Journal of Paediatric Neurology |
Volume | 19 |
Issue number | 4 |
DOIs | |
Publication status | Published - Jul 1 2015 |
Keywords
- Age factors
- Child
- Cyclosporine
- Neurotoxicity syndromes
- Seizures
- Status epilepticus
ASJC Scopus subject areas
- Clinical Neurology
- Pediatrics, Perinatology, and Child Health