Abstract

Long-term survival is rare in patients with advanced gastric cancer because most of them die of tumor recurrence within two years after the curative surgery. Surgery continues to be the mainstay of treatment, although other nonsurgical treatments have been widely researched. We report a 58-year-old female patient with a scirrhous type advanced gastric cancer. She underwent a radical subtotal gastrectomy with Billroth Ⅱ anastomosis. The surgical specimen showed an extensive submucosal and subserosal spreading, and 9 of the 34 dissected lymph nodes were involved. Thereafter, she received adjuvant chemotherapy with fluorouracil, adriamycin and mitomycin-C. She had regular follow-up thereafter. Ten years and six months later, by esophagogastroduodenoscopy, the patient was found to have a new growth tumor with only a small mucosal defect at the cardia of the remnant stomach. The patient received total resection of the remnant stomach, and the findings of the resected specimen showed an advanced scirrhous adenocarcinoma invading the whole stomach layers and the esophagus. Of the 33 resected lymph nodes, 18 of them were found positive for adenocarcinoma. This is a rare case of a patient with scirrhous gastric cancer with long-term survival, and adjuvant chemotherapy may attribute to such a clinical presentation.
Original languageEnglish
Pages (from-to)21-29
Number of pages9
JournalGastroenterological Journal of Taiwan
Volume24
Issue number1
Publication statusPublished - 2007

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Stomach Neoplasms
Survival
Gastric Stump
Adjuvant Chemotherapy
Scirrhous Adenocarcinoma
Lymph Nodes
Digestive System Endoscopy
Cardia
Mitomycin
Gastrectomy
Fluorouracil
Doxorubicin
Esophagus
Neoplasms
Stomach
Adenocarcinoma
Recurrence
Therapeutics
Growth

Keywords

  • 胃癌
  • 長期存活
  • 化療
  • gastric cancer
  • long-term survival
  • chemotherapy

Cite this

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title = "Advanced Gastric Cancer with Long-Term Survival for over Ten Years: Report of a Case",
abstract = "Long-term survival is rare in patients with advanced gastric cancer because most of them die of tumor recurrence within two years after the curative surgery. Surgery continues to be the mainstay of treatment, although other nonsurgical treatments have been widely researched. We report a 58-year-old female patient with a scirrhous type advanced gastric cancer. She underwent a radical subtotal gastrectomy with Billroth Ⅱ anastomosis. The surgical specimen showed an extensive submucosal and subserosal spreading, and 9 of the 34 dissected lymph nodes were involved. Thereafter, she received adjuvant chemotherapy with fluorouracil, adriamycin and mitomycin-C. She had regular follow-up thereafter. Ten years and six months later, by esophagogastroduodenoscopy, the patient was found to have a new growth tumor with only a small mucosal defect at the cardia of the remnant stomach. The patient received total resection of the remnant stomach, and the findings of the resected specimen showed an advanced scirrhous adenocarcinoma invading the whole stomach layers and the esophagus. Of the 33 resected lymph nodes, 18 of them were found positive for adenocarcinoma. This is a rare case of a patient with scirrhous gastric cancer with long-term survival, and adjuvant chemotherapy may attribute to such a clinical presentation.",
keywords = "胃癌, 長期存活, 化療, gastric cancer, long-term survival, chemotherapy",
author = "Chan, {Tze Sian} and Gi-Shih Lien and Yeong-Shan Cheng and Mao-Chih Hsieh and Chien-Jui Cheng",
year = "2007",
language = "English",
volume = "24",
pages = "21--29",
journal = "Gastroenterological Journal of Taiwan",
issn = "1013-7696",
publisher = "臺灣消化系醫學會",
number = "1",

}

TY - JOUR

T1 - Advanced Gastric Cancer with Long-Term Survival for over Ten Years

T2 - Report of a Case

AU - Chan, Tze Sian

AU - Lien, Gi-Shih

AU - Cheng, Yeong-Shan

AU - Hsieh, Mao-Chih

AU - Cheng, Chien-Jui

PY - 2007

Y1 - 2007

N2 - Long-term survival is rare in patients with advanced gastric cancer because most of them die of tumor recurrence within two years after the curative surgery. Surgery continues to be the mainstay of treatment, although other nonsurgical treatments have been widely researched. We report a 58-year-old female patient with a scirrhous type advanced gastric cancer. She underwent a radical subtotal gastrectomy with Billroth Ⅱ anastomosis. The surgical specimen showed an extensive submucosal and subserosal spreading, and 9 of the 34 dissected lymph nodes were involved. Thereafter, she received adjuvant chemotherapy with fluorouracil, adriamycin and mitomycin-C. She had regular follow-up thereafter. Ten years and six months later, by esophagogastroduodenoscopy, the patient was found to have a new growth tumor with only a small mucosal defect at the cardia of the remnant stomach. The patient received total resection of the remnant stomach, and the findings of the resected specimen showed an advanced scirrhous adenocarcinoma invading the whole stomach layers and the esophagus. Of the 33 resected lymph nodes, 18 of them were found positive for adenocarcinoma. This is a rare case of a patient with scirrhous gastric cancer with long-term survival, and adjuvant chemotherapy may attribute to such a clinical presentation.

AB - Long-term survival is rare in patients with advanced gastric cancer because most of them die of tumor recurrence within two years after the curative surgery. Surgery continues to be the mainstay of treatment, although other nonsurgical treatments have been widely researched. We report a 58-year-old female patient with a scirrhous type advanced gastric cancer. She underwent a radical subtotal gastrectomy with Billroth Ⅱ anastomosis. The surgical specimen showed an extensive submucosal and subserosal spreading, and 9 of the 34 dissected lymph nodes were involved. Thereafter, she received adjuvant chemotherapy with fluorouracil, adriamycin and mitomycin-C. She had regular follow-up thereafter. Ten years and six months later, by esophagogastroduodenoscopy, the patient was found to have a new growth tumor with only a small mucosal defect at the cardia of the remnant stomach. The patient received total resection of the remnant stomach, and the findings of the resected specimen showed an advanced scirrhous adenocarcinoma invading the whole stomach layers and the esophagus. Of the 33 resected lymph nodes, 18 of them were found positive for adenocarcinoma. This is a rare case of a patient with scirrhous gastric cancer with long-term survival, and adjuvant chemotherapy may attribute to such a clinical presentation.

KW - 胃癌

KW - 長期存活

KW - 化療

KW - gastric cancer

KW - long-term survival

KW - chemotherapy

M3 - Article

VL - 24

SP - 21

EP - 29

JO - Gastroenterological Journal of Taiwan

JF - Gastroenterological Journal of Taiwan

SN - 1013-7696

IS - 1

ER -