Adrenal insufficiency caused by primary aggressive non-Hodgkin's lymphoma of bilateral adrenal glands: Report of a case and literature review

C. W. Hsu, C. L. Ho, W. H H Sheu, H. J. Harn, T. Y. Chao

Research output: Contribution to journalArticlepeer-review

38 Citations (Scopus)

Abstract

A 64-year-old woman was hospitalized because of poor general condition, gastrointestinal upset, unexplained fever, electrolyte imbalance, and an incidental finding of bilateral huge adrenal masses on computerized tomography (CT) of the abdomen. Non-Hodgkin's lymphoma (NHL) of B-cell origin was proven by ultrasound-guided aspiration biopsy of the left adrenal gland. Meanwhile, primary adrenal insufficiency was confirmed by her low serum cortisol level, high ACTH level, and inadequate adrenal response to the rapid ACTH stimulation test. The diagnosis of primary adrenal NHL was supported by detailed physical examinations, bone marrow examination, and such imaging studies as CT scan and sonography. She received three courses of chemotherapy with cyclophosphamide, vincristine, and prednisolone and there was an initial transient response, but she died of sepsis and progression of NHL three and a half months later.

Original languageEnglish
Pages (from-to)151-154
Number of pages4
JournalAnnals of Hematology
Volume78
Issue number3
DOIs
Publication statusPublished - Mar 1999
Externally publishedYes

Keywords

  • Adrenal gland
  • Aggressive non-Hodgkin's lynphoma
  • Primary adrenal insufficiency

ASJC Scopus subject areas

  • Hematology

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