Adequate prenatal care reduces the risk of adverse pregnancy outcomes in women with history of infertility: A nationwide population-based study

Raushan Alibekova, Jian Pei Huang, Yi Hua Chen

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objectives: To investigate the effects of various measures of prenatal care on adverse pregnancy outcomes in women with a history of infertility. Study Design: A retrospective cohort study. Methods: Data were derived by linking 2 large nationwide population-based datasets, the National Health Insurance Research Database and Taiwan Birth Certificate Registry. The study sample included 15,056 women with an infertility diagnosis and 60,224 randomly selected women without infertility matched to the study sample by maternal age. A conditional logistic regression analysis was performed for the analysis. Results: Women diagnosed with infertility respectively had 1.39 (95% CI, 1.06-1.83), 1.15 (95% CI, 1.08-1.24), 1.13 (95% CI, 1.08-1.18), and 1.08 (95% CI, 1.05-1.12) higher odds of having very low birth weight (VLBW) babies, preterm births, labor complications, and cesarean sections (CSs) compared to women without infertility. Inadequate numbers of total and major prenatal visits and late initiation of prenatal care increased the risks of adverse pregnancy outcomes in women with infertility, especially the risk of a VLBW baby. However, no significant associations were found for the risks of adverse birth outcomes in infertile women with adequate prenatal care compared to fertile women with adequate care. Conclusions: Study findings suggest that adequate prenatal care can reduce the risk of adverse pregnancy outcomes in women with infertility.

Original languageEnglish
Article numbere84237
JournalPLoS One
Volume8
Issue number12
DOIs
Publication statusPublished - Dec 17 2013

Fingerprint

prenatal care
pregnancy outcome
Prenatal Care
Pregnancy Outcome
Infertility
Population
Health insurance
Very Low Birth Weight Infant
low birth weight
Regression analysis
infants
Logistics
Personnel
Obstetric Labor Complications
health insurance
Birth Certificates
premature birth
cesarean section
Premature Obstetric Labor
Premature Birth

Keywords

  • female infertility
  • health insurance
  • population research

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Adequate prenatal care reduces the risk of adverse pregnancy outcomes in women with history of infertility : A nationwide population-based study. / Alibekova, Raushan; Huang, Jian Pei; Chen, Yi Hua.

In: PLoS One, Vol. 8, No. 12, e84237, 17.12.2013.

Research output: Contribution to journalArticle

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