Acute lymphoblastic leukemia followed by chronic myelocytic leukemia

G. Tosato, J. Whang-Peng, A. S. Levine, D. G. Poplack

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12 Citations (Scopus)


Second hematologic malignancies occur rarely in patients previously treated for leukemia. This report describes a patient with acute lymphoblastic leukemia who remained in complete remission for 5 yr and then developed chronic myelocytic leukemia (CML). The original lymphoblasts were associated with a partial deletion of chromosome 21, while CML was associated with a classic Philadelphia marker, indicating the independent origin of the 2 leukemias.

Original languageEnglish
Pages (from-to)1033-1036
Number of pages4
Issue number5
Publication statusPublished - Dec 1 1978
Externally publishedYes


ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

Cite this

Tosato, G., Whang-Peng, J., Levine, A. S., & Poplack, D. G. (1978). Acute lymphoblastic leukemia followed by chronic myelocytic leukemia. Blood, 52(5), 1033-1036.