Acrosin activity of human sperm did not correlate with IVF

Y. S. Yang, S. U. Chen, H. N. Ho, H. F. Chen, Y. R. Lien, H. R. Lin, S. C. Huang, T. Y. Lee

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

To evaluate the predicting value of sperm acrosin activity in human, the acrosin activity index (AAI) was measured in 95 semen samples from patients participating in an IVF program. All patients had at least two mature oocytes. Of 95 patients, 84 had successful fertilization and 11 failed to fertilize all oocytes in vitro. The numbers of mature oocytes were similar between fertilization and nonfertilization groups. The mean AAI, measured using a commercially available (Accu-Sperm) acrosin activity assay, was greater in the fertilization group than in the nonfertilization group, but the difference was not significant. There was no correlation between AAI and the in vitro fertilization rate of mature oocytes. The relation between AAI and semen parameters also showed no significant difference. It would appear that measurement of AAI inaccurately reflects in vitro fertilizability of human sperm.

Original languageEnglish
Pages (from-to)13-19
Number of pages7
JournalSystems Biology in Reproductive Medicine
Volume32
Issue number1
DOIs
Publication statusPublished - Jan 1 1994
Externally publishedYes

Fingerprint

Acrosin
Human Activities
Spermatozoa
Oocytes
Fertilization
Semen
Fertilization in Vitro

Keywords

  • Acrosin
  • Enzyme
  • In vitro fertilization
  • Sperm

ASJC Scopus subject areas

  • Reproductive Medicine
  • Urology

Cite this

Yang, Y. S., Chen, S. U., Ho, H. N., Chen, H. F., Lien, Y. R., Lin, H. R., ... Lee, T. Y. (1994). Acrosin activity of human sperm did not correlate with IVF. Systems Biology in Reproductive Medicine, 32(1), 13-19. https://doi.org/10.3109/01485019408987761

Acrosin activity of human sperm did not correlate with IVF. / Yang, Y. S.; Chen, S. U.; Ho, H. N.; Chen, H. F.; Lien, Y. R.; Lin, H. R.; Huang, S. C.; Lee, T. Y.

In: Systems Biology in Reproductive Medicine, Vol. 32, No. 1, 01.01.1994, p. 13-19.

Research output: Contribution to journalArticle

Yang, YS, Chen, SU, Ho, HN, Chen, HF, Lien, YR, Lin, HR, Huang, SC & Lee, TY 1994, 'Acrosin activity of human sperm did not correlate with IVF', Systems Biology in Reproductive Medicine, vol. 32, no. 1, pp. 13-19. https://doi.org/10.3109/01485019408987761
Yang, Y. S. ; Chen, S. U. ; Ho, H. N. ; Chen, H. F. ; Lien, Y. R. ; Lin, H. R. ; Huang, S. C. ; Lee, T. Y. / Acrosin activity of human sperm did not correlate with IVF. In: Systems Biology in Reproductive Medicine. 1994 ; Vol. 32, No. 1. pp. 13-19.
@article{a71d7bd14fdc427a986729ceb8e12778,
title = "Acrosin activity of human sperm did not correlate with IVF",
abstract = "To evaluate the predicting value of sperm acrosin activity in human, the acrosin activity index (AAI) was measured in 95 semen samples from patients participating in an IVF program. All patients had at least two mature oocytes. Of 95 patients, 84 had successful fertilization and 11 failed to fertilize all oocytes in vitro. The numbers of mature oocytes were similar between fertilization and nonfertilization groups. The mean AAI, measured using a commercially available (Accu-Sperm) acrosin activity assay, was greater in the fertilization group than in the nonfertilization group, but the difference was not significant. There was no correlation between AAI and the in vitro fertilization rate of mature oocytes. The relation between AAI and semen parameters also showed no significant difference. It would appear that measurement of AAI inaccurately reflects in vitro fertilizability of human sperm.",
keywords = "Acrosin, Enzyme, In vitro fertilization, Sperm",
author = "Yang, {Y. S.} and Chen, {S. U.} and Ho, {H. N.} and Chen, {H. F.} and Lien, {Y. R.} and Lin, {H. R.} and Huang, {S. C.} and Lee, {T. Y.}",
year = "1994",
month = "1",
day = "1",
doi = "10.3109/01485019408987761",
language = "English",
volume = "32",
pages = "13--19",
journal = "Systems Biology in Reproductive Medicine",
issn = "1939-6376",
publisher = "Informa Healthcare",
number = "1",

}

TY - JOUR

T1 - Acrosin activity of human sperm did not correlate with IVF

AU - Yang, Y. S.

AU - Chen, S. U.

AU - Ho, H. N.

AU - Chen, H. F.

AU - Lien, Y. R.

AU - Lin, H. R.

AU - Huang, S. C.

AU - Lee, T. Y.

PY - 1994/1/1

Y1 - 1994/1/1

N2 - To evaluate the predicting value of sperm acrosin activity in human, the acrosin activity index (AAI) was measured in 95 semen samples from patients participating in an IVF program. All patients had at least two mature oocytes. Of 95 patients, 84 had successful fertilization and 11 failed to fertilize all oocytes in vitro. The numbers of mature oocytes were similar between fertilization and nonfertilization groups. The mean AAI, measured using a commercially available (Accu-Sperm) acrosin activity assay, was greater in the fertilization group than in the nonfertilization group, but the difference was not significant. There was no correlation between AAI and the in vitro fertilization rate of mature oocytes. The relation between AAI and semen parameters also showed no significant difference. It would appear that measurement of AAI inaccurately reflects in vitro fertilizability of human sperm.

AB - To evaluate the predicting value of sperm acrosin activity in human, the acrosin activity index (AAI) was measured in 95 semen samples from patients participating in an IVF program. All patients had at least two mature oocytes. Of 95 patients, 84 had successful fertilization and 11 failed to fertilize all oocytes in vitro. The numbers of mature oocytes were similar between fertilization and nonfertilization groups. The mean AAI, measured using a commercially available (Accu-Sperm) acrosin activity assay, was greater in the fertilization group than in the nonfertilization group, but the difference was not significant. There was no correlation between AAI and the in vitro fertilization rate of mature oocytes. The relation between AAI and semen parameters also showed no significant difference. It would appear that measurement of AAI inaccurately reflects in vitro fertilizability of human sperm.

KW - Acrosin

KW - Enzyme

KW - In vitro fertilization

KW - Sperm

UR - http://www.scopus.com/inward/record.url?scp=84907126819&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84907126819&partnerID=8YFLogxK

U2 - 10.3109/01485019408987761

DO - 10.3109/01485019408987761

M3 - Article

C2 - 8122931

AN - SCOPUS:84907126819

VL - 32

SP - 13

EP - 19

JO - Systems Biology in Reproductive Medicine

JF - Systems Biology in Reproductive Medicine

SN - 1939-6376

IS - 1

ER -