Acquired XO/XY clones in bone marrow of a patient with paroxysmal nocturnal hemoglobinuria (PNH)

J. Whang Peng, T. Knutsen, E. C. Lee, B. Leventhal

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Cytogenetic studies showed both 45XO and 46XY clones in the bone marrow of a 76 yr old male with a 17 yr history of paroxysmal nocturnal hemoglobinuria (PNH). 55Fe incorporation studies demonstrated that both clones involved the hematopoietic stem cells. The loss of the Y chromosome may reflect an aging phenomenon, rather than be related to the PNH.

Original languageEnglish
Pages (from-to)611-619
Number of pages9
JournalBlood
Volume47
Issue number4
Publication statusPublished - Dec 1 1976
Externally publishedYes

Fingerprint

Paroxysmal Hemoglobinuria
Chromosomes
Stem cells
Bone
Clone Cells
Aging of materials
Bone Marrow
History
Y Chromosome
Hematopoietic Stem Cells
Cytogenetics

ASJC Scopus subject areas

  • Immunology
  • Biochemistry
  • Hematology
  • Cell Biology

Cite this

Acquired XO/XY clones in bone marrow of a patient with paroxysmal nocturnal hemoglobinuria (PNH). / Whang Peng, J.; Knutsen, T.; Lee, E. C.; Leventhal, B.

In: Blood, Vol. 47, No. 4, 01.12.1976, p. 611-619.

Research output: Contribution to journalArticle

Whang Peng, J, Knutsen, T, Lee, EC & Leventhal, B 1976, 'Acquired XO/XY clones in bone marrow of a patient with paroxysmal nocturnal hemoglobinuria (PNH)', Blood, vol. 47, no. 4, pp. 611-619.
Whang Peng, J. ; Knutsen, T. ; Lee, E. C. ; Leventhal, B. / Acquired XO/XY clones in bone marrow of a patient with paroxysmal nocturnal hemoglobinuria (PNH). In: Blood. 1976 ; Vol. 47, No. 4. pp. 611-619.
@article{29caca9476594b2d8b37ab8ea2fcc859,
title = "Acquired XO/XY clones in bone marrow of a patient with paroxysmal nocturnal hemoglobinuria (PNH)",
abstract = "Cytogenetic studies showed both 45XO and 46XY clones in the bone marrow of a 76 yr old male with a 17 yr history of paroxysmal nocturnal hemoglobinuria (PNH). 55Fe incorporation studies demonstrated that both clones involved the hematopoietic stem cells. The loss of the Y chromosome may reflect an aging phenomenon, rather than be related to the PNH.",
author = "{Whang Peng}, J. and T. Knutsen and Lee, {E. C.} and B. Leventhal",
year = "1976",
month = "12",
day = "1",
language = "English",
volume = "47",
pages = "611--619",
journal = "Blood",
issn = "0006-4971",
publisher = "American Society of Hematology",
number = "4",

}

TY - JOUR

T1 - Acquired XO/XY clones in bone marrow of a patient with paroxysmal nocturnal hemoglobinuria (PNH)

AU - Whang Peng, J.

AU - Knutsen, T.

AU - Lee, E. C.

AU - Leventhal, B.

PY - 1976/12/1

Y1 - 1976/12/1

N2 - Cytogenetic studies showed both 45XO and 46XY clones in the bone marrow of a 76 yr old male with a 17 yr history of paroxysmal nocturnal hemoglobinuria (PNH). 55Fe incorporation studies demonstrated that both clones involved the hematopoietic stem cells. The loss of the Y chromosome may reflect an aging phenomenon, rather than be related to the PNH.

AB - Cytogenetic studies showed both 45XO and 46XY clones in the bone marrow of a 76 yr old male with a 17 yr history of paroxysmal nocturnal hemoglobinuria (PNH). 55Fe incorporation studies demonstrated that both clones involved the hematopoietic stem cells. The loss of the Y chromosome may reflect an aging phenomenon, rather than be related to the PNH.

UR - http://www.scopus.com/inward/record.url?scp=0017286459&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017286459&partnerID=8YFLogxK

M3 - Article

VL - 47

SP - 611

EP - 619

JO - Blood

JF - Blood

SN - 0006-4971

IS - 4

ER -