Acquired immunodeficiency syndrome with CNS toxoplasmosis

a case report.

C. C. Chang, S. T. Liao, S. Y. Kuo, S. J. Chu, C. M. Chen, T. Y. Shih, M. L. Chang, D. M. Chang

Research output: Contribution to journalArticle

Abstract

Central nervous system (CNS) toxoplasmosis is an important infectious complication of acquired immunodeficiency syndrome (AIDS) which appears to result from reactivation of a previously acquired infection and requires prolonged treatment. A 31-year-old male presented in a drowsy mental state and with an unstable gait. Computerized tomographic (CT) scan and magnetic resonance imaging (MRI) showed multiple nodular lesions in the cerebrum and cerebellum; the seropositivity for the human immunodeficiency virus (HIV-1) and high serum IgG toxoplasma titers were also demonstrated. A presumptive diagnosis of CNS toxoplasmosis was based on neurological signs and neuroradiological findings. This was confirmed by improvement in both clinical and neuroradiological pictures during treatment with pyrimethamine and clindamycin. Four months later, however the patient died of intracranial hemorrhage and massive upper GI bleeding.

Original languageEnglish
Pages (from-to)69-73
Number of pages5
JournalChinese Medical Journal (Taipei)
Volume55
Issue number1
Publication statusPublished - Jan 1995
Externally publishedYes

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Cerebral Toxoplasmosis
HIV-1
Acquired Immunodeficiency Syndrome
Pyrimethamine
Clindamycin
Intracranial Hemorrhages
Toxoplasma
Cerebrum
Gait
Cerebellum
Immunoglobulin G
Magnetic Resonance Imaging
Hemorrhage
Therapeutics
Infection
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Chang, C. C., Liao, S. T., Kuo, S. Y., Chu, S. J., Chen, C. M., Shih, T. Y., ... Chang, D. M. (1995). Acquired immunodeficiency syndrome with CNS toxoplasmosis: a case report. Chinese Medical Journal (Taipei), 55(1), 69-73.

Acquired immunodeficiency syndrome with CNS toxoplasmosis : a case report. / Chang, C. C.; Liao, S. T.; Kuo, S. Y.; Chu, S. J.; Chen, C. M.; Shih, T. Y.; Chang, M. L.; Chang, D. M.

In: Chinese Medical Journal (Taipei), Vol. 55, No. 1, 01.1995, p. 69-73.

Research output: Contribution to journalArticle

Chang, CC, Liao, ST, Kuo, SY, Chu, SJ, Chen, CM, Shih, TY, Chang, ML & Chang, DM 1995, 'Acquired immunodeficiency syndrome with CNS toxoplasmosis: a case report.', Chinese Medical Journal (Taipei), vol. 55, no. 1, pp. 69-73.
Chang, C. C. ; Liao, S. T. ; Kuo, S. Y. ; Chu, S. J. ; Chen, C. M. ; Shih, T. Y. ; Chang, M. L. ; Chang, D. M. / Acquired immunodeficiency syndrome with CNS toxoplasmosis : a case report. In: Chinese Medical Journal (Taipei). 1995 ; Vol. 55, No. 1. pp. 69-73.
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