Aconitamide, a novel alkaloid from the roots of Aconitum carmichaeli

Zong-Huei Li, Yu Chang Chen, Ching Kuo Lee, Hsun Shuo Chang, Ching Chuan Kuo, Che Yi Chao, Jing Jer Lin, Lee Chiang Lo, Yueh Hsiung Kuo

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Aconitum carmichaeli Debx. is a traditional Chinese medicine commonly employed for curing a wide array of diseases in East Asia. From the ethyl acetate soluble fraction of the methanolic extracts of A. carmichaeli, a new alkaloid, aconitamide (1), along with eighteen known compounds 2-19 were isolated by column chromatography and identified on the basis of spectroscopic analyses. The anti-telomerase activity of 1-19 was also assessed, but no activity was found, even at a concentration higher than 30 μM.

Original languageEnglish
Pages (from-to)827-828
Number of pages2
JournalNatural Product Communications
Issue number6
Publication statusPublished - 2013


  • Aconitamide
  • Aconitum carmichaeli Debx.
  • Anti-telomerase
  • Chinese herb
  • Ranunculaceae
  • Roots

ASJC Scopus subject areas

  • Drug Discovery
  • Pharmacology
  • Complementary and alternative medicine
  • Plant Science


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