Acalyphidins M1, M2 and D1, ellagitannins from Acalypha hispida

Yoshiaki Amakura; Masao Miyake; Hideyuki Ito; Satomi Murakaku; Sachiko Araki; Yasuyo Itoh; Che Feng Lu; Ling Ling Yang; Kun Ying Yen; Takuo Okuda; Takashi Yoshida

doi:10.1016/S0031-9422(98)00579-2

Acalyphidins M1, M2 and D1, ellagitannins from Acalypha hispida

Yoshiaki Amakura, Masao Miyake, Hideyuki Ito, Satomi Murakaku, Sachiko Araki, Yasuyo Itoh, Che Feng Lu, Ling Ling Yang, Kun Ying Yen, Takuo Okuda, Takashi Yoshida

Graduate Institute of Pharmacognosy

Research output: Contribution to journal › Article

22 Citations (Scopus)

Abstract

Two new monomeric hydrolysable tannins, acalyphidins M₁ and M₂, together with fourteen known polyphenols were isolated from the leaves of Acalypha hispida, and characterized as 1-O-galloyl-3,6-(R)- hexahydroxydiphenoyl-4-O-brevifolincarboxyl-β-D-glucose, and an oxidative metabolite of geraniin, respectively, by spectroscopic and chemical methods. A new hydrolysable tannin dimer, acalyphidin D₁, which is composed of two moles of geraniin, was also isolated and characterized as an acetonyl derivative.

Original language	English
Pages (from-to)	667-675
Number of pages	9
Journal	Phytochemistry
Volume	50
Issue number	4
DOIs	https://doi.org/10.1016/S0031-9422(98)00579-2
Publication status	Published - Feb 24 1999

Keywords

Acalypha hispida
Acalyphidin D
Acalyphidin M
Ellagitannins
Euphorbiaceae
Tannins

ASJC Scopus subject areas

Plant Science
Biochemistry
Molecular Biology
Organic Chemistry
Drug Discovery

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Amakura, Y., Miyake, M., Ito, H., Murakaku, S., Araki, S., Itoh, Y., Lu, C. F., Yang, L. L., Yen, K. Y., Okuda, T., & Yoshida, T. (1999). Acalyphidins M1, M2 and D1, ellagitannins from Acalypha hispida. Phytochemistry, 50(4), 667-675. https://doi.org/10.1016/S0031-9422(98)00579-2

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abstract = "Two new monomeric hydrolysable tannins, acalyphidins M1 and M2, together with fourteen known polyphenols were isolated from the leaves of Acalypha hispida, and characterized as 1-O-galloyl-3,6-(R)- hexahydroxydiphenoyl-4-O-brevifolincarboxyl-β-D-glucose, and an oxidative metabolite of geraniin, respectively, by spectroscopic and chemical methods. A new hydrolysable tannin dimer, acalyphidin D1, which is composed of two moles of geraniin, was also isolated and characterized as an acetonyl derivative.",

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author = "Yoshiaki Amakura and Masao Miyake and Hideyuki Ito and Satomi Murakaku and Sachiko Araki and Yasuyo Itoh and Lu, {Che Feng} and Yang, {Ling Ling} and Yen, {Kun Ying} and Takuo Okuda and Takashi Yoshida",

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AU - Amakura, Yoshiaki

AU - Miyake, Masao

AU - Ito, Hideyuki

AU - Murakaku, Satomi

AU - Araki, Sachiko

AU - Itoh, Yasuyo

AU - Lu, Che Feng

AU - Yang, Ling Ling

AU - Yen, Kun Ying

AU - Okuda, Takuo

AU - Yoshida, Takashi

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AB - Two new monomeric hydrolysable tannins, acalyphidins M1 and M2, together with fourteen known polyphenols were isolated from the leaves of Acalypha hispida, and characterized as 1-O-galloyl-3,6-(R)- hexahydroxydiphenoyl-4-O-brevifolincarboxyl-β-D-glucose, and an oxidative metabolite of geraniin, respectively, by spectroscopic and chemical methods. A new hydrolysable tannin dimer, acalyphidin D1, which is composed of two moles of geraniin, was also isolated and characterized as an acetonyl derivative.

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KW - Acalyphidin M

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KW - Euphorbiaceae

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