Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese

Huimin Fan, Xiaolin Li, Liang Zheng, Xiaoli Chen, Qin Lan, Hong Wu, Xugang Ding, Dingguang Qian, Yixin Shen, Zuoren Yu, Lieying Fan, Ming Chen, Brian Tomlinson, Paul Chan, Yuzhen Zhang, Zhongmin Liu

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Abstract

Obesity is usually considered to predispose to atherosclerotic cardiovascular disease (ASCVD) but milder degrees of obesity or overweight may be protective in some elderly populations. We examined the relationships between general and abdominal obesity indices with ASCVD and its risk factors in elderly (aged ≥65 years) Shanghai community residents Among the 3950 participants, 21.5% had ASCVD, 56.2% had body mass index (BMI) ≥24 kg/m2, 50.1% had high waist circumference (WC) and 77.1% had waist-to-height ratio (WHtR) ≥0.50. WHtR increased with age in both men and women whereas WC increased with age only in women and BMI decreased with age only in men. The optimal WHtR cut-off value to predict the risk of ASCVD determined by receiver operating characteristic analysis was WHtR ≥0.53 with a prevalence of 55.8%. Having abdominal obesity was significantly associated with prevalent ASCVD with WHtR ≥0.53 having a higher value for the odds ratio than high WC, whereas high BMI was not associated. All three indices predicted high glucose, triglycerides and hsCRP levels but only the WHtR ≥0.53 showed a significant association with physical activity. Abdominal obesity indices, but not BMI, predicted prevalent ASCVD and its risk factors in this elderly Chinese population.

Original languageEnglish
Article number21521
JournalScientific Reports
Volume6
DOIs
Publication statusPublished - Feb 17 2016

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Independent Living
Abdominal Obesity
Cardiovascular Diseases
Waist Circumference
Body Mass Index
Obesity
ROC Curve
Population
Waist-Height Ratio
Triglycerides
Odds Ratio
Exercise
Glucose

ASJC Scopus subject areas

  • General

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Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese. / Fan, Huimin; Li, Xiaolin; Zheng, Liang; Chen, Xiaoli; Lan, Qin; Wu, Hong; Ding, Xugang; Qian, Dingguang; Shen, Yixin; Yu, Zuoren; Fan, Lieying; Chen, Ming; Tomlinson, Brian; Chan, Paul; Zhang, Yuzhen; Liu, Zhongmin.

In: Scientific Reports, Vol. 6, 21521, 17.02.2016.

Research output: Contribution to journalArticle

Fan, H, Li, X, Zheng, L, Chen, X, Lan, Q, Wu, H, Ding, X, Qian, D, Shen, Y, Yu, Z, Fan, L, Chen, M, Tomlinson, B, Chan, P, Zhang, Y & Liu, Z 2016, 'Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese', Scientific Reports, vol. 6, 21521. https://doi.org/10.1038/srep21521
Fan, Huimin ; Li, Xiaolin ; Zheng, Liang ; Chen, Xiaoli ; Lan, Qin ; Wu, Hong ; Ding, Xugang ; Qian, Dingguang ; Shen, Yixin ; Yu, Zuoren ; Fan, Lieying ; Chen, Ming ; Tomlinson, Brian ; Chan, Paul ; Zhang, Yuzhen ; Liu, Zhongmin. / Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese. In: Scientific Reports. 2016 ; Vol. 6.
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