Most people in Taiwan acquire their drug guidelines or pharmaceutical information from the medical professionals of healthcare providers. However, based on the current health insurance policy, the healthcare providers can hardly afford the patient education for the public. Hence, it is important to develop pharmaceutical education information systems in which people can easily inquire the knowledge of their diseases, medication and drug guidelines to compensate the inadequacy of patient education. In this project we developed a web-based pharmaceutical education information system based on an individual profile of his/her prescriptions. The profile can automatically be built up by accessing the related hospital information systems. We also designed a multimedia drug database containing the outlooks of drug items, drug guidelines, summaries of drug use, and links to relevant materials. Thus, a patient can access his/her drug information by keying his account name, date of birth and password. This system can help patients to get the information. Although when patients obtained more medical knowledge, they may induce the questions or asks to doctors who might consider them as annoyance. As a matter of fact, patients will be empowered by the Internet, and can access more medical knowledge. Thus, medical professionals should adopt this change, and catch up the most advanced knowledge to improve doctor-patient relationships.