A three-dimensional microwell perfusion-array for oocytes zona-removal and incubation

C. W. Lee, C. Chang, Y. L. Lin, L. C. Pan, F. G. Tseng

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Zona-free oocyte is widely used in in-vitro fertilization (IVF) to solve low implantation rate of IVF [1]. The process of zona-removal is tedious and also easy to harm the fragile oocyte. To simplify the zona-removal process, a three-dimensional microfluidic device with a composite porous PDMS membrane is employed in this work. Through a gentle perfusion process, this device is capable to keep oocyte intact throughout the zona-removal procedure.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages417-418
Number of pages2
ISBN (Electronic)9780979806490
Publication statusPublished - 2016
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: Oct 9 2016Oct 13 2016

Publication series

Name20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period10/9/1610/13/16

Keywords

  • IVF
  • Microfluidic
  • Zona-free oocyte

ASJC Scopus subject areas

  • Control and Systems Engineering

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