A three-dimensional microwell perfusion-array for oocytes zona-removal and incubation

C. W. Lee, C. Chang, Y. L. Lin, L. C. Pan, F. G. Tseng

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Zona-free oocyte is widely used in in-vitro fertilization (IVF) to solve low implantation rate of IVF [1]. The process of zona-removal is tedious and also easy to harm the fragile oocyte. To simplify the zona-removal process, a three-dimensional microfluidic device with a composite porous PDMS membrane is employed in this work. Through a gentle perfusion process, this device is capable to keep oocyte intact throughout the zona-removal procedure.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages417-418
Number of pages2
ISBN (Electronic)9780979806490
Publication statusPublished - 2016
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: Oct 9 2016Oct 13 2016

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period10/9/1610/13/16

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Keywords

  • IVF
  • Microfluidic
  • Zona-free oocyte

ASJC Scopus subject areas

  • Control and Systems Engineering

Cite this

Lee, C. W., Chang, C., Lin, Y. L., Pan, L. C., & Tseng, F. G. (2016). A three-dimensional microwell perfusion-array for oocytes zona-removal and incubation. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (pp. 417-418). Chemical and Biological Microsystems Society.