A Ten Year Experience in Total Body Irradiation in BMT Patients

雷 德, 丁 禮莉(Lai-Lei Ting), 王 博民, 鍾 娜娜, 方 麗麗

Research output: Contribution to journalArticle

Abstract

Total body irradiation is the popular treatment of lymphopoietic malignancies and preparation for bone marrow transplantation. Hyperfractionated radiation regimen was to deliver a total dose of 1200 cGy in 8 fractions, 3 fractions a day for 2.5 days. One HVL (half value layer) alloy lung shield is being used to minimize pulmonary toxicitiy. Acute toxic effects included reversible gastroenteritis, mucositis, and myelosuppression. Delayed toxic effects include interstitial pneumonitis, cataract formation and GVHD. Interstitial pneumonitis is one of the major causes of morbidity and mortality after bone marrow transplantation. Pulmonary toxicity occurred in 26 (56.5%) cases and 16 of them died from IP. In 15 infected cases, 5 were classified as IP with infectious agent of cytomegalo-virus. The other cases without infectious agent were classified as idiopathic IP (IIP), which occurred in 23.9% of the TBI patients.
Original languageEnglish
Pages (from-to)77-80
Number of pages4
JournalChinese Journal of Radiology
Volume21
Issue number2
Publication statusPublished - 1996
Externally publishedYes

Fingerprint

Whole-Body Irradiation
Poisons
Interstitial Lung Diseases
Bone Marrow Transplantation
Lung
Mucositis
Gastroenteritis
Cataract
Radiation
Viruses
Morbidity
Mortality
Neoplasms
Therapeutics

Keywords

  • 骨髓移植
  • 全身放射線照射
  • Total body irradiation
  • Bone marrow transplantation

Cite this

A Ten Year Experience in Total Body Irradiation in BMT Patients. / 雷德; 丁禮莉(Lai-Lei Ting); 王博民; 鍾娜娜; 方麗麗.

In: Chinese Journal of Radiology, Vol. 21, No. 2, 1996, p. 77-80.

Research output: Contribution to journalArticle

雷德, 丁禮莉(Lai-LeiT, 王博民, 鍾娜娜 & 方麗麗 1996, 'A Ten Year Experience in Total Body Irradiation in BMT Patients', Chinese Journal of Radiology, vol. 21, no. 2, pp. 77-80.
雷德 ; 丁禮莉(Lai-Lei Ting) ; 王博民 ; 鍾娜娜 ; 方麗麗. / A Ten Year Experience in Total Body Irradiation in BMT Patients. In: Chinese Journal of Radiology. 1996 ; Vol. 21, No. 2. pp. 77-80.
@article{87f9a3252c5e4821b0977538fd0e4774,
title = "A Ten Year Experience in Total Body Irradiation in BMT Patients",
abstract = "Total body irradiation is the popular treatment of lymphopoietic malignancies and preparation for bone marrow transplantation. Hyperfractionated radiation regimen was to deliver a total dose of 1200 cGy in 8 fractions, 3 fractions a day for 2.5 days. One HVL (half value layer) alloy lung shield is being used to minimize pulmonary toxicitiy. Acute toxic effects included reversible gastroenteritis, mucositis, and myelosuppression. Delayed toxic effects include interstitial pneumonitis, cataract formation and GVHD. Interstitial pneumonitis is one of the major causes of morbidity and mortality after bone marrow transplantation. Pulmonary toxicity occurred in 26 (56.5{\%}) cases and 16 of them died from IP. In 15 infected cases, 5 were classified as IP with infectious agent of cytomegalo-virus. The other cases without infectious agent were classified as idiopathic IP (IIP), which occurred in 23.9{\%} of the TBI patients.",
keywords = "骨髓移植, 全身放射線照射, Total body irradiation, Bone marrow transplantation, total body irradiation, Bone marrow transplantation",
author = "德 雷 and 丁, {禮莉(Lai-Lei Ting)} and 博民 王 and 娜娜 鍾 and 麗麗 方",
year = "1996",
language = "English",
volume = "21",
pages = "77--80",
journal = "Chinese Journal of Radiology",
issn = "1018-8940",
publisher = "中華民國放射線醫學會",
number = "2",

}

TY - JOUR

T1 - A Ten Year Experience in Total Body Irradiation in BMT Patients

AU - 雷, 德

AU - 丁, 禮莉(Lai-Lei Ting)

AU - 王, 博民

AU - 鍾, 娜娜

AU - 方, 麗麗

PY - 1996

Y1 - 1996

N2 - Total body irradiation is the popular treatment of lymphopoietic malignancies and preparation for bone marrow transplantation. Hyperfractionated radiation regimen was to deliver a total dose of 1200 cGy in 8 fractions, 3 fractions a day for 2.5 days. One HVL (half value layer) alloy lung shield is being used to minimize pulmonary toxicitiy. Acute toxic effects included reversible gastroenteritis, mucositis, and myelosuppression. Delayed toxic effects include interstitial pneumonitis, cataract formation and GVHD. Interstitial pneumonitis is one of the major causes of morbidity and mortality after bone marrow transplantation. Pulmonary toxicity occurred in 26 (56.5%) cases and 16 of them died from IP. In 15 infected cases, 5 were classified as IP with infectious agent of cytomegalo-virus. The other cases without infectious agent were classified as idiopathic IP (IIP), which occurred in 23.9% of the TBI patients.

AB - Total body irradiation is the popular treatment of lymphopoietic malignancies and preparation for bone marrow transplantation. Hyperfractionated radiation regimen was to deliver a total dose of 1200 cGy in 8 fractions, 3 fractions a day for 2.5 days. One HVL (half value layer) alloy lung shield is being used to minimize pulmonary toxicitiy. Acute toxic effects included reversible gastroenteritis, mucositis, and myelosuppression. Delayed toxic effects include interstitial pneumonitis, cataract formation and GVHD. Interstitial pneumonitis is one of the major causes of morbidity and mortality after bone marrow transplantation. Pulmonary toxicity occurred in 26 (56.5%) cases and 16 of them died from IP. In 15 infected cases, 5 were classified as IP with infectious agent of cytomegalo-virus. The other cases without infectious agent were classified as idiopathic IP (IIP), which occurred in 23.9% of the TBI patients.

KW - 骨髓移植

KW - 全身放射線照射

KW - Total body irradiation

KW - Bone marrow transplantation

KW - total body irradiation

KW - Bone marrow transplantation

M3 - Article

VL - 21

SP - 77

EP - 80

JO - Chinese Journal of Radiology

JF - Chinese Journal of Radiology

SN - 1018-8940

IS - 2

ER -