A simple and robust PET-based anthracene-appended O-N-O chelate for sequential recognition of Fe3+/CN ions in aqueous media and its multimodal applications

Anup Pandith, Jun Hyeak Choi, Ok Sang Jung, Hong Seok Kim

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

A very simple, robust, and pico/nanomolar-sensitive 9,10-diethanolamine-substituted fluorescent Fe3+/CN probe (PD) was synthesised, and its sensing abilities towards various ions were studied in mixed aqueous media. PD selectively recognised Fe3+ ions through a ‘turn on’ response with an excellent binding constant (Ka, 9.29 × 106 M−1) in 1:2 binding stoichiometry at pH 7.0 in phosphate-buffered saline (PBS). The in situ generated Fe3+·PD ensemble sequentially recognised CN ions with an excellent binding constant (Ka 1.72 × 108 M−1) via a ‘turn off’ mode by extruding Fe3+ ions from the ensemble. The highly selective sequential ‘on-off’ responses towards Fe3+ and CN ions were attributed to inhibition and restoration of photoinduced electron transfer (PET) and chelation-induced enhanced fluorescence (CHEF) effects from the chelating N and O heteroatoms. PD was able to detect Fe3+ and CN ions in real water samples satisfactorily at picomolar to sub-nanomolar levels. A colorimetric assay based on pyrocatechol violet (PCV) was also able to detect Fe3+/CN in a sequential manner (up to sub-micromolar level) by a change in colour from colourless to yellow/pale green without any interferences from other ions. Based on the complexation and decomplexation mechanism, bio-imaging photonic INHIBIT logic circuit strips were prepared for use under physiological conditions. In addition, solid-phase recognition of Fe3+/CN ions was demonstrated using cost-effective paper-based strips.

Original languageEnglish
Pages (from-to)669-680
Number of pages12
JournalInorganica Chimica Acta
Volume482
DOIs
Publication statusPublished - Oct 1 2018
Externally publishedYes

Keywords

  • BIO-imaging and photonic INHIBIT logic circuit
  • Chelation-induced enhanced fluorescence
  • Photoinduced electron transfer

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry
  • Materials Chemistry

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