A potential solution to minimally invasive device for oral surgery: Evaluation of surgical outcomes in rat

Keng Liang Ou, Li Hsiang Lin, Hsi Jen Chiang, Han Yi Cheng, Shyuan Yow Chen, Chiung Fang Huang

Research output: Contribution to journalArticle

Abstract

The objective of the present research was to investigate the thermal injury in the brain after minimally invasive electrosurgery using instruments with copper-doped diamond-like carbon (DLC-Cu) surface coating. The surface morphologies of DLC-Cu thin films were characterized using scanning electron microscopy and atomic force microscopy. Three-dimensional brain models were reconstructed using magnetic resonance imaging to simulate the electrosurgical operation. In adult rats, a monopolar electrosurgical instrument coated with the DLC-Cu thin film was used to generate lesions in the brain. Animals were sacrificed for evaluations on postoperative days 0, 2, 7, and 28. Data indicated that the temperature decreased significantly when minimally invasive electrosurgical instruments with nanostructure DLC-Cu thin films were used and continued to decrease with increasing film thickness. On the other hand, the DLC-Cu-treated device created a relatively small thermal injury area and lateral thermal effect in the brain tissues. These results indicated that the DLC-Cu thin film minimized excessive thermal injury and uniformly distributed the temperature in the brain. Taken together, our study results suggest that the DLC-Cu film on copper electrode substrates is an effective means for improving the performance of electrosurgical instruments.

Original languageEnglish
Article number481854
JournalJournal of Nanomaterials
Volume2015
DOIs
Publication statusPublished - 2015

Fingerprint

Surgery
Rats
Brain
Thin films
Copper
Electrosurgery
Brain models
Diamond
Magnetic resonance
Thermal effects
Surface morphology
Film thickness
Atomic force microscopy
Nanostructures
Diamonds
Animals
Carbon
Tissue
Imaging techniques
Coatings

ASJC Scopus subject areas

  • Materials Science(all)

Cite this

A potential solution to minimally invasive device for oral surgery : Evaluation of surgical outcomes in rat. / Ou, Keng Liang; Lin, Li Hsiang; Chiang, Hsi Jen; Cheng, Han Yi; Chen, Shyuan Yow; Huang, Chiung Fang.

In: Journal of Nanomaterials, Vol. 2015, 481854, 2015.

Research output: Contribution to journalArticle

Ou, Keng Liang ; Lin, Li Hsiang ; Chiang, Hsi Jen ; Cheng, Han Yi ; Chen, Shyuan Yow ; Huang, Chiung Fang. / A potential solution to minimally invasive device for oral surgery : Evaluation of surgical outcomes in rat. In: Journal of Nanomaterials. 2015 ; Vol. 2015.
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