Abstract

Objectives/Hypothesis Whereas the impression that poor oral hygiene is linked to the development of sialolithiasis may be widely accepted, very few studies provide evidence to support this. This study therefore aimed to evaluate the association between chronic periodontitis (CP) and the subsequent development of salivary gland stone based on a nationwide coverage database. Study Design A case-control study. Methods A total of 987 subjects with sialolithiasis were included as cases. In a ratio of five controls per case, 4,935 controls matched in terms of sex and age group were selected. Conditional logistic regression analysis was performed to determine the possible association of sialolithiasis with previously diagnosed CP. Results The prevalence of prior CP between cases and controls demonstrated that 1,831 (30.9%) out of the 5,922 sampled subjects had prior CP. By Chi-square test, there was a significant difference in the prevalence of prior CP between the cases and controls (36.8% vs. 29.7%, P <0.001). By conditional logistic regression analysis, the odds ratio (OR) of prior CP for cases was 1.37 (95% confidence interval [CI], 1.19-1.56) compared to the controls after adjusting for geographic location and tobacco use. Further analyzing the relationship between sialolithiasis and prior CP according to sex, sialolithiasis was associated with prior CP regardless of sex. The adjusted OR of prior CP for the cases was 1.34 (95% CI, 1.10-1.64) and 1.41 (95% CI, 1.15-1.73) for males and females, respectively, when compared to controls. Conclusion This study demonstrates an association between CP and sialolithiasis.

Original languageEnglish
Pages (from-to)847-850
Number of pages4
JournalLaryngoscope
Volume126
Issue number4
DOIs
Publication statusPublished - Apr 1 2016

Fingerprint

Salivary Gland Calculi
Chronic Periodontitis
Population
Confidence Intervals
Logistic Models
Odds Ratio
Regression Analysis
Geographic Locations
Oral Hygiene
Tobacco Use
Chi-Square Distribution
Case-Control Studies
Age Groups

Keywords

  • chronic periodontitis
  • epidemiology
  • sialolithiasis

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

A population-based study on the association between chronic periodontitis and sialolithiasis. / Hung, Shih Han; Huang, Hung Meng; Lee, Hsin Chien; Ching Lin, Herng; Kao, Li Ting; Wu, Chuan Song.

In: Laryngoscope, Vol. 126, No. 4, 01.04.2016, p. 847-850.

Research output: Contribution to journalArticle

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abstract = "Objectives/Hypothesis Whereas the impression that poor oral hygiene is linked to the development of sialolithiasis may be widely accepted, very few studies provide evidence to support this. This study therefore aimed to evaluate the association between chronic periodontitis (CP) and the subsequent development of salivary gland stone based on a nationwide coverage database. Study Design A case-control study. Methods A total of 987 subjects with sialolithiasis were included as cases. In a ratio of five controls per case, 4,935 controls matched in terms of sex and age group were selected. Conditional logistic regression analysis was performed to determine the possible association of sialolithiasis with previously diagnosed CP. Results The prevalence of prior CP between cases and controls demonstrated that 1,831 (30.9{\%}) out of the 5,922 sampled subjects had prior CP. By Chi-square test, there was a significant difference in the prevalence of prior CP between the cases and controls (36.8{\%} vs. 29.7{\%}, P <0.001). By conditional logistic regression analysis, the odds ratio (OR) of prior CP for cases was 1.37 (95{\%} confidence interval [CI], 1.19-1.56) compared to the controls after adjusting for geographic location and tobacco use. Further analyzing the relationship between sialolithiasis and prior CP according to sex, sialolithiasis was associated with prior CP regardless of sex. The adjusted OR of prior CP for the cases was 1.34 (95{\%} CI, 1.10-1.64) and 1.41 (95{\%} CI, 1.15-1.73) for males and females, respectively, when compared to controls. Conclusion This study demonstrates an association between CP and sialolithiasis.",
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