A new prostaglandin transformed from arachidonic acid in carrageenin-induced granuloma

Wen Chang Chang, Sei itsu Murota, Mitsuyoshi Matsuo, Susumu Tsurufuji

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

A main product (PII) transformed from arachidonic acid in carrageenin-induced granuloma in rats was structurally analysed. PII was converted to a more polar substance by the reduction of sodium borohydride. According to the analysis of gas chromatography-mass spectrometry, its structure was speculated to be 9α,11α,15α-trihydroxy-6-oxo-prostenoic acid.

Original languageEnglish
Pages (from-to)1259-1264
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume72
Issue number4
DOIs
Publication statusPublished - Oct 18 1976
Externally publishedYes

Fingerprint

Keto Acids
Carrageenan
Granuloma
Arachidonic Acid
Gas chromatography
Gas Chromatography-Mass Spectrometry
Prostaglandins
Mass spectrometry
Rats
prostenoic acids
sodium borohydride

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

A new prostaglandin transformed from arachidonic acid in carrageenin-induced granuloma. / Chang, Wen Chang; Murota, Sei itsu; Matsuo, Mitsuyoshi; Tsurufuji, Susumu.

In: Biochemical and Biophysical Research Communications, Vol. 72, No. 4, 18.10.1976, p. 1259-1264.

Research output: Contribution to journalArticle

Chang, Wen Chang ; Murota, Sei itsu ; Matsuo, Mitsuyoshi ; Tsurufuji, Susumu. / A new prostaglandin transformed from arachidonic acid in carrageenin-induced granuloma. In: Biochemical and Biophysical Research Communications. 1976 ; Vol. 72, No. 4. pp. 1259-1264.
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