A new γ-lactone from the leaves of Cinnamomum kotoense

Sien Sing Yang; Wen Chi Hou; Li Wei Huang; Zong-Huei Li

doi:10.1080/14786410600906236

A new γ-lactone from the leaves of Cinnamomum kotoense

Sien Sing Yang, Wen Chi Hou, Li Wei Huang, Zong-Huei Li

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

A new C ₁₉ γ-lactone, cinnakotolactone (1), along with a known analogue, isolinderanolide B (2), were isolated from the n-hexane layer of the leaf extracts of Cinnamomum kotoense. Their structures were elucidated on the basis of spectroscopic analysis. The anti-proliferation activities of 1 and 2 were evaluated against human HT29 and MCF-7 cancer cell lines, and their IC ₅₀ values ranged from 3.3 ± 0.3 to 25.8 ± 5.3 μM.

Original language	English
Pages (from-to)	1246-1250
Number of pages	5
Journal	Natural Product Research
Volume	20
Issue number	13
DOIs	https://doi.org/10.1080/14786410600906236
Publication status	Published - Nov 2006

Keywords

Anti-proliferation activity
Cinnakotolactone
Cinnamomum kotoense
Lauraceae
Leaves

ASJC Scopus subject areas

Molecular Medicine
Plant Science
Chemistry(all)
Biochemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/14786410600906236

Cite this

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abstract = "A new C 19 γ-lactone, cinnakotolactone (1), along with a known analogue, isolinderanolide B (2), were isolated from the n-hexane layer of the leaf extracts of Cinnamomum kotoense. Their structures were elucidated on the basis of spectroscopic analysis. The anti-proliferation activities of 1 and 2 were evaluated against human HT29 and MCF-7 cancer cell lines, and their IC 50 values ranged from 3.3 ± 0.3 to 25.8 ± 5.3 μM.",

keywords = "Anti-proliferation activity, Cinnakotolactone, Cinnamomum kotoense, Lauraceae, Leaves",

author = "Yang, {Sien Sing} and Hou, {Wen Chi} and Huang, {Li Wei} and Zong-Huei Li",

year = "2006",

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AU - Hou, Wen Chi

AU - Huang, Li Wei

AU - Li, Zong-Huei

PY - 2006/11

Y1 - 2006/11

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AB - A new C 19 γ-lactone, cinnakotolactone (1), along with a known analogue, isolinderanolide B (2), were isolated from the n-hexane layer of the leaf extracts of Cinnamomum kotoense. Their structures were elucidated on the basis of spectroscopic analysis. The anti-proliferation activities of 1 and 2 were evaluated against human HT29 and MCF-7 cancer cell lines, and their IC 50 values ranged from 3.3 ± 0.3 to 25.8 ± 5.3 μM.

KW - Anti-proliferation activity

KW - Cinnakotolactone

KW - Cinnamomum kotoense

KW - Lauraceae

KW - Leaves

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ER -

A new γ-lactone from the leaves of Cinnamomum kotoense

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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