A nationwide population-based study on bladder pain syndrome/interstitial cystitis and ED

S. D. Chung, J. Keller, H. C. Lin

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As bladder pain syndrome/interstitial cystitis (BPS/IC) has been demonstrated to proceed through the inflammatory pathways to cause endothelial dysfunction, and endothelial dysfunction is a major factor in the development of ED, it is possible that BPS/IC may be associated with ED. This study set out to investigate the putative association between ED and BPS/IC by using a population-based data set and case-control design in Taiwan. We obtained the data from Taiwan's National Health Insurance Research Database. Cases included 32 856 ED patients ≥18-years old and 164 280 matched controls. Conditional logistic regression analyses were performed to compare the odds ratios (OR) and corresponding 95% confidence intervals (CIs) of having been previously diagnosed with BPS/IC in cases and controls. Among the total sample of 197 136 subjects, the prevalence of prior BPS/IC was 0.05%. The prevalence of prior BPS/IC was 0.10% and 0.04% for cases and controls, respectively (P

Original languageEnglish
Pages (from-to)224-228
Number of pages5
JournalInternational Journal of Impotence Research
Issue number6
Publication statusPublished - Nov 2013



  • BPS/IC
  • ED
  • Epidemiology

ASJC Scopus subject areas

  • Urology

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