A facile method for the synthesis of glaucine and norglaucine from boldine

Wei Jan Huang, Chung Hsiung Chen, Om V. Singh, Su Lin Lee, Shoei Sheng Lee

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

A large-scale preparation of glaucine was achieved by reacting boldine with trimethylphenylammonium chloride and potassium t-butoxide in high yield. Treatment of glaucine with 30% H202, subsequent with hydrated ferrous sulfate, afforded norglaucine in an overall yield of 40%.

Original languageEnglish
Pages (from-to)3681-3686
Number of pages6
JournalSynthetic Communications
Volume32
Issue number23
DOIs
Publication statusPublished - 2002
Externally publishedYes

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ferrous sulfate
Potassium Chloride
glaucine
boldine

Keywords

  • Glaucine
  • Large-scale preparation
  • Norglaucine

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

A facile method for the synthesis of glaucine and norglaucine from boldine. / Huang, Wei Jan; Chen, Chung Hsiung; Singh, Om V.; Lee, Su Lin; Lee, Shoei Sheng.

In: Synthetic Communications, Vol. 32, No. 23, 2002, p. 3681-3686.

Research output: Contribution to journalArticle

Huang, Wei Jan ; Chen, Chung Hsiung ; Singh, Om V. ; Lee, Su Lin ; Lee, Shoei Sheng. / A facile method for the synthesis of glaucine and norglaucine from boldine. In: Synthetic Communications. 2002 ; Vol. 32, No. 23. pp. 3681-3686.
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