A controlled study of therapeutic endoscopy for peptic ulcer with non-bleeding visible vessel

H. J. Lin, F. Y. Lee, W. M. Kang, Y. T. Tsai, S. D. Lee, C. H. Lee

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

In a period of 14 months, a prospective, randomized, controlled trial was undertaken in 61 patients who had bled from peptic ulcers in which, at endoscopy, non-bleeding vessels were visible in the ulcer crater. The control group consisted of 31 patients in whom the procedure was limited to observation alone; in 30 patients the ulcer base was coagulated by means of a heat probe. There were no statistically significant differences between the two groups in the rate of rebleeding, the assurance of ultimate hemostasis, the volume of blood transfusion required, the duration of hospitalization, or eventual mortality. However, the need for emergency surgical intervention was less frequent in the heat probe group (2 of 30) than among the controls (9 of 31) (p = 0.0243). Moreover, in the treatment group, those patients of advanced age (>60 years), in shock, requiring blood transfusion of >500 ml, and in whom blood or coffee ground material was seen in the stomach, thermocoagulation achieved statistically more effective hemostasis than that observed in the control group. For these high-risk subsets of patients with non-bleeding visible vessels, we recommend heat probe coagulation rather than mere observation.

Original languageEnglish
Pages (from-to)241-246
Number of pages6
JournalGastrointestinal Endoscopy
Volume36
Issue number3
Publication statusPublished - 1990
Externally publishedYes

Fingerprint

Peptic Ulcer
Endoscopy
Hot Temperature
Hemostasis
Blood Transfusion
Ulcer
Observation
Therapeutics
Control Groups
Electrocoagulation
Coffee
Shock
Stomach
Hospitalization
Emergencies
Randomized Controlled Trials
Mortality

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Lin, H. J., Lee, F. Y., Kang, W. M., Tsai, Y. T., Lee, S. D., & Lee, C. H. (1990). A controlled study of therapeutic endoscopy for peptic ulcer with non-bleeding visible vessel. Gastrointestinal Endoscopy, 36(3), 241-246.

A controlled study of therapeutic endoscopy for peptic ulcer with non-bleeding visible vessel. / Lin, H. J.; Lee, F. Y.; Kang, W. M.; Tsai, Y. T.; Lee, S. D.; Lee, C. H.

In: Gastrointestinal Endoscopy, Vol. 36, No. 3, 1990, p. 241-246.

Research output: Contribution to journalArticle

Lin, HJ, Lee, FY, Kang, WM, Tsai, YT, Lee, SD & Lee, CH 1990, 'A controlled study of therapeutic endoscopy for peptic ulcer with non-bleeding visible vessel', Gastrointestinal Endoscopy, vol. 36, no. 3, pp. 241-246.
Lin, H. J. ; Lee, F. Y. ; Kang, W. M. ; Tsai, Y. T. ; Lee, S. D. ; Lee, C. H. / A controlled study of therapeutic endoscopy for peptic ulcer with non-bleeding visible vessel. In: Gastrointestinal Endoscopy. 1990 ; Vol. 36, No. 3. pp. 241-246.
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