A computer simulation model for cost-effectiveness analysis of mass screening for Type 2 diabetes mellitus

Tony Hsiu Hsi Chen, Ming Fang Yen, Tao Hsin Tung

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The cost-effectiveness analysis of mass screening for Type 2 diabetes mellitus (DM) was performed to elucidate whether, who and how often it should be conducted in Taiwan. A series of Markov process was developed to model the disease natural history of Type 2 DM. A hypothetical cohort with 30 000 residents aged over 30 years in Taiwan was randomly assigned to three arms of screening regimes, biennial, five-yearly and the control group. A Monteo Carol computer simulation was performed to calculate effectiveness of two screening regimes compared with the control group. Direct costs and utilities were incorporated to each corresponding state to calculate the incremental costs per life-years gained and per quality-adjusted life-years (QALYs) for biennial and five-yearly screening regimes. The incremental costs for biennial screening regime were estimated at $26 750 per life-year gained, and $17 833 per QALY. The corresponding figures for five-yearly screening regime were $10 531 per life-year gained and $17 113 per QALY. The incremental costs per life-year gained and per QALY increase with age, ranging from $17 238 for aged 30-39 years to $54 700 for aged over 70 years and from $9193 to 36 467, respectively. In conclusion, mass screening for Type 2 DM, especially in younger subjects, with 5-year inter-screening interval is cost-effective in Taiwan.

Original languageEnglish
JournalDiabetes Research and Clinical Practice
Volume54
Issue numberSUPPL. 1
Publication statusPublished - 2001
Externally publishedYes

Fingerprint

Mass Screening
Computer Simulation
Quality-Adjusted Life Years
Type 2 Diabetes Mellitus
Cost-Benefit Analysis
Costs and Cost Analysis
Taiwan
Markov Chains
Control Groups

Keywords

  • Cost-effectiveness analysis
  • Markov model
  • Mass screening
  • Monte Carol computer simulation
  • Type 2 diabetes mellitus

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

A computer simulation model for cost-effectiveness analysis of mass screening for Type 2 diabetes mellitus. / Chen, Tony Hsiu Hsi; Yen, Ming Fang; Tung, Tao Hsin.

In: Diabetes Research and Clinical Practice, Vol. 54, No. SUPPL. 1, 2001.

Research output: Contribution to journalArticle

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