A comparison of outcomes between liver transplant recipients in China and those in Taiwan

Teng-Wei Chen, Chih-Yung Yu, Heng-Cheng Chu, De-Chuan Chan, Guo-Shiou Liao, Chung-Bao Hsieh

Research output: Contribution to journalArticle

Abstract

Background: The outcome of liver transplantation in Taiwan and overseas has not been compared directly. We investigated differences in outcomes between liver transplant recipients in China and those in Taiwan. Materials and Methods: Ninety-two patients who underwent liver transplantation in China and were subsequently being followed at the Tri- Service General Hospital (TSGH; China group; CG) were compared with 107 patients who received transplants at TSGH (Taiwan group; TG). Donor and recipient characteristics, complications, and survival were analyzed. Survival was calculated using the Kaplan-Meier method, and univariate analysis was tested by the log-rank test. Then, regression analysis was performed using the Cox proportional hazard model. Results: The number of patients with hepatocellular carcinoma (HCC) beyond the Milan and University of California, San Francisco criteria was signifi cantly higher in the CG than in the TG. The rates of HCC recurrence, intrahepatic biliary strictures, and mortality were also higher in the CG than in the TG. Univariate analysis revealed signifi cant differences in 8 parameters between survivors and non-survivors, and Cox regression analysis further identifi ed psychosocial problems, post-transplant de novo malignancy, HCC recurrence, and graft failure as mortality predictors. The overall survival rate was signifi cantly higher in the TG than in the CG, with the former group showing a trend of greater mean survival duration. However, differences in survival were not signifi cant after adjusting for risk factors. Conclusion: The outcomes of patients receiving livers donated after cardiac death may be comparable; however, patients with advanced HCC should not seek transplantation without appropriate pre-transplant tumor treatments. © 2013 JMS.
Original languageEnglish
Pages (from-to)311-319
Number of pages9
JournalJournal of Medical Sciences (Taiwan)
Volume33
Issue number6
DOIs
Publication statusPublished - 2013
Externally publishedYes

Fingerprint

Taiwan
China
Hepatocellular Carcinoma
Liver
Transplants
Survival
Liver Transplantation
Regression Analysis
Recurrence
San Francisco
Mortality
Proportional Hazards Models
General Hospitals
Survivors
Neoplasms
Pathologic Constriction
Survival Rate
Transplantation
Transplant Recipients
Tissue Donors

Keywords

  • Brain death
  • Donation after cardiac death
  • Down-stage therapy
  • Liver transplantation
  • Survival
  • adult
  • article
  • bile leakage
  • cancer recurrence
  • cerebrovascular accident
  • China
  • cholangitis
  • cholestasis
  • common bile duct stone
  • erythrophagocytosis
  • female
  • graft failure
  • hepatitis B
  • human
  • liver cell carcinoma
  • liver transplantation
  • major clinical study
  • male
  • middle aged
  • mortality
  • overall survival
  • risk factor
  • Taiwan
  • treatment outcome

Cite this

A comparison of outcomes between liver transplant recipients in China and those in Taiwan. / Chen, Teng-Wei; Yu, Chih-Yung; Chu, Heng-Cheng; Chan, De-Chuan; Liao, Guo-Shiou; Hsieh, Chung-Bao.

In: Journal of Medical Sciences (Taiwan), Vol. 33, No. 6, 2013, p. 311-319.

Research output: Contribution to journalArticle

Chen, Teng-Wei ; Yu, Chih-Yung ; Chu, Heng-Cheng ; Chan, De-Chuan ; Liao, Guo-Shiou ; Hsieh, Chung-Bao. / A comparison of outcomes between liver transplant recipients in China and those in Taiwan. In: Journal of Medical Sciences (Taiwan). 2013 ; Vol. 33, No. 6. pp. 311-319.
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title = "A comparison of outcomes between liver transplant recipients in China and those in Taiwan",
abstract = "Background: The outcome of liver transplantation in Taiwan and overseas has not been compared directly. We investigated differences in outcomes between liver transplant recipients in China and those in Taiwan. Materials and Methods: Ninety-two patients who underwent liver transplantation in China and were subsequently being followed at the Tri- Service General Hospital (TSGH; China group; CG) were compared with 107 patients who received transplants at TSGH (Taiwan group; TG). Donor and recipient characteristics, complications, and survival were analyzed. Survival was calculated using the Kaplan-Meier method, and univariate analysis was tested by the log-rank test. Then, regression analysis was performed using the Cox proportional hazard model. Results: The number of patients with hepatocellular carcinoma (HCC) beyond the Milan and University of California, San Francisco criteria was signifi cantly higher in the CG than in the TG. The rates of HCC recurrence, intrahepatic biliary strictures, and mortality were also higher in the CG than in the TG. Univariate analysis revealed signifi cant differences in 8 parameters between survivors and non-survivors, and Cox regression analysis further identifi ed psychosocial problems, post-transplant de novo malignancy, HCC recurrence, and graft failure as mortality predictors. The overall survival rate was signifi cantly higher in the TG than in the CG, with the former group showing a trend of greater mean survival duration. However, differences in survival were not signifi cant after adjusting for risk factors. Conclusion: The outcomes of patients receiving livers donated after cardiac death may be comparable; however, patients with advanced HCC should not seek transplantation without appropriate pre-transplant tumor treatments. {\circledC} 2013 JMS.",
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author = "Teng-Wei Chen and Chih-Yung Yu and Heng-Cheng Chu and De-Chuan Chan and Guo-Shiou Liao and Chung-Bao Hsieh",
note = "Export Date: 22 March 2016 通訊地址: Hsieh, C.-B.; Division of General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Cheng-gong Road, Taipei 114, Taiwan; 電子郵件: albert0920@yahoo.com.tw 參考文獻: Ravaioli, M., Ercolani, G., Cescon, M., Vetrone, G., Voci, C., Grigioni, W.F., D'Errico, A., Grazi, G.L., Liver transplantation for hepatocellular carcinoma: Further consideration on selection criteria (2004) Liver Transpl, 10, pp. 1195-1202. , doi: 10.1002/ lt.20239; Ringe, B., Strong, R.W., The dilemma of living liver donor death: To report or not to report (2008) Transplantation, 85, pp. 790-793. , doi: 10.1097/TP.0b013e318167345e; Fan, S.T., Wang, H., Lam, B.K., Follow-up of Chinese liver transplant recipients in Hong Kong (2009) Liver Transpl, 15, pp. 544-550. , doi: 10.1002/lt.21720; Dindo, D., Demartines, N., Clavien, P.M., Classification of surgical complications. A new proposal with evaluation in a cohort of 6336 patients and results of a survey (2004) Ann Surg, 240, pp. 205-213; Muiesan, P., Girlanda, R., Jassem, W., Melendez, H.V., O'Grady, J., Bowles, M., Rela, M., Heaton, N., Singlecenter experience with liver transplantation from controlled non-heart beating donors: A viable source of grafts (2005) Ann Surg, 242, pp. 732-738; Abt, P., Crawford, M., Desai, N., Markmann, J., Olthoff, K., Shaked, A., Liver transplantation from controlled nonheart beating donors: An increase incidence of biliary complications (2003) Transplantation, 75, pp. 1659-1663; Fukumori, T., Kato, T., Levi, D., Olson, L., Nishida, S., Ganz, S., Nakamura, N., Tzakis, A., Use of older controlled non-heart-beating donors for liver transplantation (2003) Transplantation, 75, pp. 1171-1174; D'Alessandro, A.M., Hoffmann, R.M., Knechtle, S.J., Odorico, J.S., Becker, Y.T., Musat, A., Pirsch, J.D., Kalayoglu, M., Liver transplantation from controlled non heart-beating donors (2000) Surgery, 128, pp. 579-588; Monbaliu, D., Van Gelder, F., Troisi, R., de Hemptinne, B., Lerut, J., Reding, R., de Ville de Goyet, J., Pirenne, J., Liver transplantation using non heart-beating donors: Belgian experience (2007) Transplant Proc, 39, pp. 1481-1484; Suarez, F., Otero, A., Solla, M., Arnal, F., Lorenzo, M.J., Marini, M., V{\'a}zquez-Iglesias, J.L., G{\'o}mez, M., Biliary complications after liver transplantation from Maastricht category-2 non-heart beating donors (2008) Transplantation, 85, pp. 9-14. , doi: 10.1097/01. tp.0000297945.83430.ce; Sawyer, R.G., Punch, J.D., Incidence and management of biliary complications after 291 liver transplants following the introduction of transcystic stenting (1998) Transplantation, 66, pp. 1201-1207; Hernandez, Q., Ramirez, P., Munitiz, V., Pi{\~n}ero, A., Robles, R., Sanchez-Bueno, F., Rodriguez, J.M., Parrilla, P., Incidence and management of biliary tract complications following 300 consecutive orthotopic liver transplants (1999) Transplant Proc, 31, pp. 2407-2408; Rerknimitr, R., Sherman, S., Fogel, E.L., Kalayci, C., Lumeng, L., Chalasani, N., Kwo, P., Lehman, G.A., Biliary tract complications after orthotopic liver transplantation with choledo-chocholedochostomy anastomosis: Endoscopic fi ndings and results of therapy (2002) Gastrointest Endosc, 55, pp. 224-231; Park, J.S., Kim, M.H., Lee, S.K., Seo, D.W., Lee, S.S., Han, J., Min, Y.I., Sung, K.B., Effi cacy of endoscopic and percutaneous treatments for biliary complications after cadaveric and living donor liver transplantation (2003) Gastrointest Endosc, 57, pp. 78-85; Qian, Y.B., Liu, C.L., Lo, C.M., Fan, S.T., Risk factors for biliary complications after liver transplantation (2004) Arch Surg, 139, pp. 1101-1105; Thethy, S., Thomson, B.N., Pleass, H., Wigmore, S.J., Madhavan, K., Akyol, M., Forsythe, J.L., James Garden, O., Management of biliary tract complications after orthotopic liver transplantation (2004) Clin Transplant, 18, pp. 647-653; Hsieh, C.B., Chou, S.J., Shih, M.L., Chu, H.C., Chu, C.H., Yu, J.C., Yao, N.S., Preliminary experience with gemcitabine and cisplatin adjuvant chemotherapy after liver transplantation for hepatocellular carcinoma (2008) European Journal of Surgical Oncology (EJSO), 34, pp. 906-910. , doi: 10.1016/j.ejso.2007.11.014; Ravaioli, M., Grazi, G.L., Piscaglia, F., Trevisani, F., Cescon, M., Ercolani, G., Vivarelli, M., Pinna, A.D., Liver transplantation for hepatocellular carcinoma: Results of down-staging in patients initially outside the Milan selection criteria (2008) Am J Transplant, pp. 2547-2557. , doi: 10.1111/ j.1600-6143.2008.02409.x; de Luna, W., Sze, D.Y., Ahmed, A., Ha, B.Y., Ayoub, W., Keeffe, E.B., Cooper, A., Nguyen, M.H., Transarterial chemoinfusion for hepatocellular carcinoma as downstaging therapy and a bridge toward liver transplantation (2009) Am J Transplant, 9, pp. 1158-1168. , doi: 10.1111/j.1600-6143.2009.02576.x; Levenson, J., Olbrisch, M., Psychosocial evaluation of organ transplant candidates. A comparative survey of process, criteria, and outcomes in heart, liver, and kidney transplantation (1993) Psychosomatics, 34, pp. 314-323; Twillman, R., Manetto, C., Wellisch, D.K., Wolcott, D.L., The Transplant Evaluation Rating Scale. A revision of the psychosocial levels system for evaluating organ transplant candidates (1993) Psychosomatics, 34, pp. 144-153; Olbrisch, M., Levenson, J., Hamer, R., The PACT: A rating scale for the study of clinical decision-making in psychosocial screening of organ transolant candidates (1989) Clin Transplant, 3, pp. 164-169; Yates, W., Martin, M., Labrecque, D., Hillebrand, D., Voigt, M., Pfab, D., A model to examine the validity of the 6-month abstinence criterion for liver transplantation (1998) Alcohol Clin Exp Res, 22, pp. 513-517; Platz, K., Mueller, A., Spree, E., Schumacher, G., N{\"u}ssler, N.C., Rayes, N., Glanemann, M., Neuhaus, P., Liver transplantation for alcoholic cirrhosis (2000) Transpl Int, 13, pp. S127-S130; Saigal, S., Norris, S., Muiesan, P., Rela, M., Heaton, N., O'Grady, J., Evidence of differential risk for posttransplantation malignancy based on pretransplantation cause in patients undergoing liver transplantation (2002) Liver Transpl, 8, pp. 482-487; Jain, A., Dimartini, A., Kashyap, R., Youk, A., Rohal, S., Fung, J., Long-term follow-up after liver transplantation for alcoholic liver disease under tacrolimus (2000) Transplantation, 70, pp. 1335-1342; Sheiner, P.A., Magliocca, J.F., Bodian, C.A., Kim-Schluger, L., Altaca, G., Guarrera, J.V., Emre, S., Miller, C.M., Long-term medical complications in patients surviving ≥ 5 years after liver transplant (2000) Transplantation, 69, pp. 781-789; Watt, K.D., Pedersen, R.A., Kremers, W.K., Heimbach, J.K., Sanchez, W., Gores, G.J., Long-term probability of and mortality from de novo malignancy after liver transplantation (2009) Gastroenterology, 137, pp. 2010-2017. , doi: 10.1053/j.gastro.2009.08.070",
year = "2013",
doi = "10.6136/JMS.2013.33(6).311",
language = "English",
volume = "33",
pages = "311--319",
journal = "Journal of Medical Sciences",
issn = "1011-4564",
publisher = "國防醫學院",
number = "6",

}

TY - JOUR

T1 - A comparison of outcomes between liver transplant recipients in China and those in Taiwan

AU - Chen, Teng-Wei

AU - Yu, Chih-Yung

AU - Chu, Heng-Cheng

AU - Chan, De-Chuan

AU - Liao, Guo-Shiou

AU - Hsieh, Chung-Bao

N1 - Export Date: 22 March 2016 通訊地址: Hsieh, C.-B.; Division of General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Cheng-gong Road, Taipei 114, Taiwan; 電子郵件: albert0920@yahoo.com.tw 參考文獻: Ravaioli, M., Ercolani, G., Cescon, M., Vetrone, G., Voci, C., Grigioni, W.F., D'Errico, A., Grazi, G.L., Liver transplantation for hepatocellular carcinoma: Further consideration on selection criteria (2004) Liver Transpl, 10, pp. 1195-1202. , doi: 10.1002/ lt.20239; Ringe, B., Strong, R.W., The dilemma of living liver donor death: To report or not to report (2008) Transplantation, 85, pp. 790-793. , doi: 10.1097/TP.0b013e318167345e; Fan, S.T., Wang, H., Lam, B.K., Follow-up of Chinese liver transplant recipients in Hong Kong (2009) Liver Transpl, 15, pp. 544-550. , doi: 10.1002/lt.21720; Dindo, D., Demartines, N., Clavien, P.M., Classification of surgical complications. A new proposal with evaluation in a cohort of 6336 patients and results of a survey (2004) Ann Surg, 240, pp. 205-213; Muiesan, P., Girlanda, R., Jassem, W., Melendez, H.V., O'Grady, J., Bowles, M., Rela, M., Heaton, N., Singlecenter experience with liver transplantation from controlled non-heart beating donors: A viable source of grafts (2005) Ann Surg, 242, pp. 732-738; Abt, P., Crawford, M., Desai, N., Markmann, J., Olthoff, K., Shaked, A., Liver transplantation from controlled nonheart beating donors: An increase incidence of biliary complications (2003) Transplantation, 75, pp. 1659-1663; Fukumori, T., Kato, T., Levi, D., Olson, L., Nishida, S., Ganz, S., Nakamura, N., Tzakis, A., Use of older controlled non-heart-beating donors for liver transplantation (2003) Transplantation, 75, pp. 1171-1174; D'Alessandro, A.M., Hoffmann, R.M., Knechtle, S.J., Odorico, J.S., Becker, Y.T., Musat, A., Pirsch, J.D., Kalayoglu, M., Liver transplantation from controlled non heart-beating donors (2000) Surgery, 128, pp. 579-588; Monbaliu, D., Van Gelder, F., Troisi, R., de Hemptinne, B., Lerut, J., Reding, R., de Ville de Goyet, J., Pirenne, J., Liver transplantation using non heart-beating donors: Belgian experience (2007) Transplant Proc, 39, pp. 1481-1484; Suarez, F., Otero, A., Solla, M., Arnal, F., Lorenzo, M.J., Marini, M., Vázquez-Iglesias, J.L., Gómez, M., Biliary complications after liver transplantation from Maastricht category-2 non-heart beating donors (2008) Transplantation, 85, pp. 9-14. , doi: 10.1097/01. tp.0000297945.83430.ce; Sawyer, R.G., Punch, J.D., Incidence and management of biliary complications after 291 liver transplants following the introduction of transcystic stenting (1998) Transplantation, 66, pp. 1201-1207; Hernandez, Q., Ramirez, P., Munitiz, V., Piñero, A., Robles, R., Sanchez-Bueno, F., Rodriguez, J.M., Parrilla, P., Incidence and management of biliary tract complications following 300 consecutive orthotopic liver transplants (1999) Transplant Proc, 31, pp. 2407-2408; Rerknimitr, R., Sherman, S., Fogel, E.L., Kalayci, C., Lumeng, L., Chalasani, N., Kwo, P., Lehman, G.A., Biliary tract complications after orthotopic liver transplantation with choledo-chocholedochostomy anastomosis: Endoscopic fi ndings and results of therapy (2002) Gastrointest Endosc, 55, pp. 224-231; Park, J.S., Kim, M.H., Lee, S.K., Seo, D.W., Lee, S.S., Han, J., Min, Y.I., Sung, K.B., Effi cacy of endoscopic and percutaneous treatments for biliary complications after cadaveric and living donor liver transplantation (2003) Gastrointest Endosc, 57, pp. 78-85; Qian, Y.B., Liu, C.L., Lo, C.M., Fan, S.T., Risk factors for biliary complications after liver transplantation (2004) Arch Surg, 139, pp. 1101-1105; Thethy, S., Thomson, B.N., Pleass, H., Wigmore, S.J., Madhavan, K., Akyol, M., Forsythe, J.L., James Garden, O., Management of biliary tract complications after orthotopic liver transplantation (2004) Clin Transplant, 18, pp. 647-653; Hsieh, C.B., Chou, S.J., Shih, M.L., Chu, H.C., Chu, C.H., Yu, J.C., Yao, N.S., Preliminary experience with gemcitabine and cisplatin adjuvant chemotherapy after liver transplantation for hepatocellular carcinoma (2008) European Journal of Surgical Oncology (EJSO), 34, pp. 906-910. , doi: 10.1016/j.ejso.2007.11.014; Ravaioli, M., Grazi, G.L., Piscaglia, F., Trevisani, F., Cescon, M., Ercolani, G., Vivarelli, M., Pinna, A.D., Liver transplantation for hepatocellular carcinoma: Results of down-staging in patients initially outside the Milan selection criteria (2008) Am J Transplant, pp. 2547-2557. , doi: 10.1111/ j.1600-6143.2008.02409.x; de Luna, W., Sze, D.Y., Ahmed, A., Ha, B.Y., Ayoub, W., Keeffe, E.B., Cooper, A., Nguyen, M.H., Transarterial chemoinfusion for hepatocellular carcinoma as downstaging therapy and a bridge toward liver transplantation (2009) Am J Transplant, 9, pp. 1158-1168. , doi: 10.1111/j.1600-6143.2009.02576.x; Levenson, J., Olbrisch, M., Psychosocial evaluation of organ transplant candidates. A comparative survey of process, criteria, and outcomes in heart, liver, and kidney transplantation (1993) Psychosomatics, 34, pp. 314-323; Twillman, R., Manetto, C., Wellisch, D.K., Wolcott, D.L., The Transplant Evaluation Rating Scale. A revision of the psychosocial levels system for evaluating organ transplant candidates (1993) Psychosomatics, 34, pp. 144-153; Olbrisch, M., Levenson, J., Hamer, R., The PACT: A rating scale for the study of clinical decision-making in psychosocial screening of organ transolant candidates (1989) Clin Transplant, 3, pp. 164-169; Yates, W., Martin, M., Labrecque, D., Hillebrand, D., Voigt, M., Pfab, D., A model to examine the validity of the 6-month abstinence criterion for liver transplantation (1998) Alcohol Clin Exp Res, 22, pp. 513-517; Platz, K., Mueller, A., Spree, E., Schumacher, G., Nüssler, N.C., Rayes, N., Glanemann, M., Neuhaus, P., Liver transplantation for alcoholic cirrhosis (2000) Transpl Int, 13, pp. S127-S130; Saigal, S., Norris, S., Muiesan, P., Rela, M., Heaton, N., O'Grady, J., Evidence of differential risk for posttransplantation malignancy based on pretransplantation cause in patients undergoing liver transplantation (2002) Liver Transpl, 8, pp. 482-487; Jain, A., Dimartini, A., Kashyap, R., Youk, A., Rohal, S., Fung, J., Long-term follow-up after liver transplantation for alcoholic liver disease under tacrolimus (2000) Transplantation, 70, pp. 1335-1342; Sheiner, P.A., Magliocca, J.F., Bodian, C.A., Kim-Schluger, L., Altaca, G., Guarrera, J.V., Emre, S., Miller, C.M., Long-term medical complications in patients surviving ≥ 5 years after liver transplant (2000) Transplantation, 69, pp. 781-789; Watt, K.D., Pedersen, R.A., Kremers, W.K., Heimbach, J.K., Sanchez, W., Gores, G.J., Long-term probability of and mortality from de novo malignancy after liver transplantation (2009) Gastroenterology, 137, pp. 2010-2017. , doi: 10.1053/j.gastro.2009.08.070

PY - 2013

Y1 - 2013

N2 - Background: The outcome of liver transplantation in Taiwan and overseas has not been compared directly. We investigated differences in outcomes between liver transplant recipients in China and those in Taiwan. Materials and Methods: Ninety-two patients who underwent liver transplantation in China and were subsequently being followed at the Tri- Service General Hospital (TSGH; China group; CG) were compared with 107 patients who received transplants at TSGH (Taiwan group; TG). Donor and recipient characteristics, complications, and survival were analyzed. Survival was calculated using the Kaplan-Meier method, and univariate analysis was tested by the log-rank test. Then, regression analysis was performed using the Cox proportional hazard model. Results: The number of patients with hepatocellular carcinoma (HCC) beyond the Milan and University of California, San Francisco criteria was signifi cantly higher in the CG than in the TG. The rates of HCC recurrence, intrahepatic biliary strictures, and mortality were also higher in the CG than in the TG. Univariate analysis revealed signifi cant differences in 8 parameters between survivors and non-survivors, and Cox regression analysis further identifi ed psychosocial problems, post-transplant de novo malignancy, HCC recurrence, and graft failure as mortality predictors. The overall survival rate was signifi cantly higher in the TG than in the CG, with the former group showing a trend of greater mean survival duration. However, differences in survival were not signifi cant after adjusting for risk factors. Conclusion: The outcomes of patients receiving livers donated after cardiac death may be comparable; however, patients with advanced HCC should not seek transplantation without appropriate pre-transplant tumor treatments. © 2013 JMS.

AB - Background: The outcome of liver transplantation in Taiwan and overseas has not been compared directly. We investigated differences in outcomes between liver transplant recipients in China and those in Taiwan. Materials and Methods: Ninety-two patients who underwent liver transplantation in China and were subsequently being followed at the Tri- Service General Hospital (TSGH; China group; CG) were compared with 107 patients who received transplants at TSGH (Taiwan group; TG). Donor and recipient characteristics, complications, and survival were analyzed. Survival was calculated using the Kaplan-Meier method, and univariate analysis was tested by the log-rank test. Then, regression analysis was performed using the Cox proportional hazard model. Results: The number of patients with hepatocellular carcinoma (HCC) beyond the Milan and University of California, San Francisco criteria was signifi cantly higher in the CG than in the TG. The rates of HCC recurrence, intrahepatic biliary strictures, and mortality were also higher in the CG than in the TG. Univariate analysis revealed signifi cant differences in 8 parameters between survivors and non-survivors, and Cox regression analysis further identifi ed psychosocial problems, post-transplant de novo malignancy, HCC recurrence, and graft failure as mortality predictors. The overall survival rate was signifi cantly higher in the TG than in the CG, with the former group showing a trend of greater mean survival duration. However, differences in survival were not signifi cant after adjusting for risk factors. Conclusion: The outcomes of patients receiving livers donated after cardiac death may be comparable; however, patients with advanced HCC should not seek transplantation without appropriate pre-transplant tumor treatments. © 2013 JMS.

KW - Brain death

KW - Donation after cardiac death

KW - Down-stage therapy

KW - Liver transplantation

KW - Survival

KW - adult

KW - article

KW - bile leakage

KW - cancer recurrence

KW - cerebrovascular accident

KW - China

KW - cholangitis

KW - cholestasis

KW - common bile duct stone

KW - erythrophagocytosis

KW - female

KW - graft failure

KW - hepatitis B

KW - human

KW - liver cell carcinoma

KW - liver transplantation

KW - major clinical study

KW - male

KW - middle aged

KW - mortality

KW - overall survival

KW - risk factor

KW - Taiwan

KW - treatment outcome

U2 - 10.6136/JMS.2013.33(6).311

DO - 10.6136/JMS.2013.33(6).311

M3 - Article

VL - 33

SP - 311

EP - 319

JO - Journal of Medical Sciences

JF - Journal of Medical Sciences

SN - 1011-4564

IS - 6

ER -