A chip for catching, separating, and transporting bio-particles with dielectrophoresis

Jung Tang Huang, Guo Chen Wang, Kuang Ming Tseng, Shiuh Bin Fang

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

This study aims at developing a 3D device for catching, separating, and transporting bio-particles based on dielectrophoresis (DEP). Target particles can be simultaneously caught and transported using the negative DEP method. In non-uniform electric fields, the levitation height or complex permittivity of certain particle may be different from that of another and this property can facilitate separation of particles. We have designed and constructed a 3D device consisting of two layers of electrodes separated by a channel formed by 50 μm thick photoresist. The electrodes can operate effectively with 10-15 V and 5-7 MHz to catch all particles in the channel, and can move particles after switching the electric field to 5-15 V and 500-1,000 KHz. Hence, particles experienced coupling force of two different directional twDEP forces, and tallied with our estimation to move along the coupling direction.

Original languageEnglish
Pages (from-to)1551-1557
Number of pages7
JournalJournal of Industrial Microbiology and Biotechnology
Volume35
Issue number11
DOIs
Publication statusPublished - Nov 2008
Externally publishedYes

Keywords

  • Biochip
  • Catching
  • Dielectrophoresis
  • Separating
  • Transporting

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology

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