A Case Report of Microcystic Adnesal Carcinoma Treated with Mohs Micrographic Surgery

Perng-Nian Chu, Kuo-Liang Cheng, Kuo-Hsien Wang, Yun-Ho Lin, Woan-Ruoh Lee

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Microcystic adnexal carcinoma is a rare cutaneous appendageal malignancy, which is characterized by local aggressiveness. Histopathologically and immuno-histopathologically, the tumor reveals mixed eccrine and pilar differentiation. To date, Mohs micrographic surgery providcs a more effective therapy and better outcome than traditional wide excision. We report a 66-year-old male with a slowly growing whitish indurated plaque approaching his left nasolabial area for at least 20 years. A diagnostic biopsy showed deeply infiltrating cords and strands of tumor cells with eccrine-like and pilar-like differentiation surrounded by a sclerotic stroma. Microcystic adenxal carcinoma was diagnosed and Mohs micrographic surgery was performed consequently. This is the first reported case treated with Mohs micrographic surgery in Taiwan.
Original languageEnglish
Pages (from-to)301-305
Number of pages5
JournalDermatologica Sinica
Issue number4
Publication statusPublished - 2004



  • Microcystic adnexal carcinoma
  • Mohs micrographic surgery

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