We report a case of advanced hepatocellular carcinoma (HCC) with tumor thrombosis extending from the inferior vena cava (IVC) towards the right atrium (RA) treated by radiation therapy (RT) and targeted therapy with sorafenib. A 55-year old man who had been a hepatitis C carrier eventually developed liver cirrhosis and primary HCC. Tumor thrombosis spanning across the IVC and the RA was noted at initial diagnosis. He received RT with 37.5 Gy in 15 fractions in addition to concurrent and sequential sorafenib therapy. Follow-up imaging studies showed complete response of IVC and RA thrombus.
- Hepatocellular carcinoma
- Radiation therapy
何俊慜(Chin-Beng H, 邱仲峰(Jeng-Fong C, 郭嘉駿(Chia-Chun K, 丁禮莉(Lai-Lei T, 陳尚文(Shang-Wen C, 常慧如(Hui-Ju C, & 李欣倫 (2016). A CASE OF HEPATOCELLULAR CARCINOMA WITH TUMOR THROMBUS EXTENDING FROM THE INFERIOR VENA CAVA TOWARDS THE RIGHT ATRIUM SHOWS COMPLETE RESPONSE AFTER COMBINED TREATMENT WITH RADIATION THERAPY AND SORAFENIB. 放射治療與腫瘤學, 23(3), 205-212. https://doi.org/10.6316/TRO/201623(3)205