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  Activation of dopamine D₂-like receptors attenuates pulmonary C-fiber hypersensitivity in rats

  Lin, Y. S., Gu, Q. & Lee, L. Y., Apr 15 2003, In: American Journal of Respiratory and Critical Care Medicine. 167, 8, p. 1096-1101 6 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Activation of estrogen receptor is crucial for resveratrol-stimulating muscular glucose uptake via both insulin-dependent and -independent pathways

  Deng, J. Y., Hsieh, P. S., Huang, J. P., Lu, L. S. & Hung, L. M., Jul 2008, In: Diabetes. 57, 7, p. 1814-1823 10 p.

  Research output: Contribution to journal › Article › peer-review
  130 Citations (Scopus)

• Activation of estrogen receptors with E2 downregulates peroxisome proliferator-activated receptor γ in hepatocellular carcinoma

  Lin, Y. M., Velmurugan, B. K., Yeh, Y. L., Tu, C. C., Ho, T. J., Lai, T-I., Tsai, C. H., Tsai, F. J., Tsai, C. H. & Huang, C. Y., Dec 2013, In: Oncology Reports. 30, 6, p. 3027-3031 5 p.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• Activation of extracellular signal-regulated kinase (ERK)1/2, but not p38 and c-Jun N-terminal kinase, is involved in signaling of a novel cytokine, ML-1

  Kawaguchi, M., Onuchic, L. F. & Huang, S. K., May 3 2002, In: Journal of Biological Chemistry. 277, 18, p. 15229-15232 4 p.

  Research output: Contribution to journal › Article › peer-review
  39 Citations (Scopus)

• Activation of extracellular signal-regulated kinase signaling by epidermal growth factor mediates c-Jun activation and p300 recruitment in keratin 16 gene expression

  Wang, Y. N., Chen, Y. J. & Chang, W. C., Jan 2006, In: Molecular Pharmacology. 69, 1, p. 85-98 14 p.

  Research output: Contribution to journal › Article › peer-review
  37 Citations (Scopus)

• Activation of fibroblast growth factor 8 gene expression in human embryonal carcinoma cells

  Wu, J., Payson, R. A., Lang, J. C. & Chiu, I. M., May 1997, In: Journal of Steroid Biochemistry and Molecular Biology. 62, 1, p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Activation of fibroblasts by nicotine promotes the epithelial-mesenchymal transition and motility of breast cancer cells

  Chen, P. C., Lee, W. Y., Ling, H. H., Cheng, C. H., Chen, K. C. & Lin, C. W., Jun 2018, In: Journal of Cellular Physiology. 233, 6, p. 4972-4980 9 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• Activation of free fatty acid receptor 1 improves hepatic steatosis through a p38-dependent pathway

  Ou, H. Y., Wu, H. T., Lu, F. H., Su, Y. C., Hung, H. C., Wu, J. S., Yang, Y. C., Wu, C. L. & Chang, C. J., Jul 9 2014, In: Journal of Molecular Endocrinology. 53, 2, p. 165-174 10 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Activation of gonadotropin-releasing hormone receptors produces neuronal excitation in the rat hippocampus

  Lu, F., Yang, J. M., Wu, J. N., Chen, Y. C., Kao, Y. H., Tung, C. S. & Yang, S. N., 1999, In: Chinese Journal of Physiology. 42, 2, p. 67-71 5 p.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• Activation of heme oxygenase-1 by Ginkgo biloba extract differentially modulates endothelial and smooth muscle-like progenitor cells for vascular repair

  Wu, T. C., Chen, J. S., Wang, C. H., Huang, P. H., Lin, F. Y., Lin, L. Y., Lin, S. J. & Chen, J. W., Dec 1 2019, In: Scientific Reports. 9, 1, 17316.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Citations (Scopus)

• Activation of human orbital fibroblasts through CD40 engagement results in a dramatic induction of hyaluronan synthesis and prostaglandin endoperoxide H synthase-2 expression: Insights into potential pathogenic mechanisms of thyroid-associated ophthalmopathy

  Cao, H. J., Wang, H. S., Zhang, Y., Lin, H. Y., Phipps, R. P. & Smith, T. J., Nov 6 1998, In: Journal of Biological Chemistry. 273, 45, p. 29615-29625 11 p.

  Research output: Contribution to journal › Article › peer-review
  180 Citations (Scopus)

• Activation of human telomerase reverse transcriptase expression by some new symmetrical bis-substituted derivatives of the anthraquinone

  Huang, H. S., Chiou, J. F., Fong, Y., Hou, C. C., Lu, Y. C., Wang, J. Y., Shih, J. W., Pan, Y. R. & Lin, J. J., Jul 17 2003, In: Journal of Medicinal Chemistry. 46, 15, p. 3300-3307 8 p.

  Research output: Contribution to journal › Article › peer-review
  60 Citations (Scopus)

• Activation of IGF-I survival signaling and its compensative inhibition of the cardiac apoptosis on carotid arteries balloon-injured rat hearts

  Hsieh, C. H., Pai, P., Wu, J. P., Ho, T. J., Wu, C. H., Shibu, M. A., Day, C. H., Viswanadha, V. P., Chuang, H. L. & Huang, C. Y., 2017, In: Chinese Journal of Physiology. 60, 3, p. 166-173 8 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Activation of IL6/IGFIR confers poor prognosis of HBV-related hepatocellular carcinoma through induction of OCT4/NANOG expression

  Chang, T. S., Wu, Y. C., Chi, C. C., Su, W. C., Chang, P. J., Lee, K. F., Tung, T. H., Wang, J., Liu, J-J., Tung, S. Y., Kuo, L. M., Ho, H. N., Ling, T. Y. & Huang, Y-H., Jan 1 2015, In: Clinical Cancer Research. 21, 1, p. 201-210 10 p.

  Research output: Contribution to journal › Article › peer-review
  78 Citations (Scopus)

• Activation of imidazoline I2B receptors is linked with AMP kinase pathway to increase glucose uptake in cultured C₂C₁₂ cells

  Lui, T. N., Tsao, C. W., Huang, S. Y., Chang, C. H. & Cheng, J. T., May 2010, In: Neuroscience Letters. 474, 3, p. 144-147 4 p.

  Research output: Contribution to journal › Article › peer-review
  25 Citations (Scopus)

• Activation of indices of cell-mediated immunity in bipolar mania

  Tsai, S. Y., Chen, K. P., Yang, Y. Y., Chen, C. C., Lee, J-C., Singh, V. K. & Leu, S. J. C., Apr 15 1999, In: Biological Psychiatry. 45, 8, p. 989-994 6 p.

  Research output: Contribution to journal › Article › peer-review
  104 Citations (Scopus)

• Activation of iodosobenzene by catalytic tetrabutylammonium iodide and its application in the oxidation of some isoquinoline alkaloids

  Huang, W. J., Singh, O. V., Chen, C. H., Chiou, S. Y. & Lee, S. S., 2002, In: Helvetica Chimica Acta. 85, 4, p. 1069-1078 10 p.

  Research output: Contribution to journal › Article › peer-review
  33 Citations (Scopus)

• Activation of JNK contributes to evodiamine-induced apoptosis and G ₂/M arrest in human colorectal carcinoma cells: A structure-activity study of evodiamine

  Chien, C. C., Wu, M. S., Shen, S. C., Ko, C. H., Chen, C. H., Yang, L. L. & Chen, Y. C., Jun 24 2014, In: PLoS One. 9, 6, e99729.

  Research output: Contribution to journal › Article › peer-review
  61 Citations (Scopus)

• Activation of kelch-like ECH-associated protein 1/nuclear factor erythroid 2-related factor 2/antioxidant response element pathway by curcumin enhances the anti-oxidative capacity of corneal endothelial cells

  Guo, S. P., Chang, H. C., Lu, L. S., Liu, D. Z. & Wang, T. J., Sept 2021, In: Biomedicine and Pharmacotherapy. 141, 111834.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Activation of MEK2 is sufficient to induce skin papilloma formation in transgenic zebrafish Application of Zebrafish in Biomedical Research

  Chou, C. M., Chen, Y. C., Su, S., Chen, G. D., Huang, K. Y., Lien, H. W., Huang, C. J. & Cheng, C. H., Nov 17 2015, In: Journal of Biomedical Science. 22, 1, 102.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Activation of mitogen-activated protein kinase by oxidized low-density lipoprotein in canine cultured vascular smooth muscle cells

  Yang, C. M., Chiu, C. T., Wang, C. C., Chien, C. S., Hsiao, L. D., Lin, C. C., Tu, M. T. & Pan, S. L., Apr 2000, In: Cellular Signalling. 12, 4, p. 205-214 10 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• Activation of muscarinic M-3 receptor may decrease glucose uptake and lipolysis in adipose tissue of rats

  Yang, T. T., Chang, C. K., Tsao, C. W., Hsu, Y. M., Hsu, C. T. & Cheng, J. T., Feb 13 2009, In: Neuroscience Letters. 451, 1, p. 57-59 3 p.

  Research output: Contribution to journal › Article › peer-review
  25 Citations (Scopus)

• Activation of NF-κB by SOD2 promotes the aggressiveness of lung adenocarcinoma by modulating NKX2-1-mediated IKKβ expression

  Chen, P. M., Wu, T. C., Wang, Y. C., Cheng, Y. W., Sheu, G. T., Chen, C. Y. & Lee, H., Nov 2013, In: Carcinogenesis. 34, 11, p. 2655-2663 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  33 Citations (Scopus)

• Activation of NPFFR2 leads to hyperalgesia through the spinal inflammatory mediator CGRP in mice

  Lin, Y. T., Liu, H. L., Day, Y. J., Chang, C. C., Hsu, P. H. & Chen, J. C., May 2017, In: Experimental Neurology. 291, p. 62-73 12 p.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• Activation of Nrf2/HO-1signaling pathway involves the anti-inflammatory activity of magnolol in Porphyromonas gingivalis lipopolysaccharide-stimulated mouse RAW 264.7 macrophages

  Lu, S. H., Hsu, W. L., Chen, T. H. & Chou, T. C., Dec 1 2015, In: International Immunopharmacology. 29, 2, p. 770-778 9 p.

  Research output: Contribution to journal › Article › peer-review
  37 Citations (Scopus)

• Activation of Nrf2 by Esculetin Mitigates Inflammatory Responses through Suppression of NF-κB Signaling Cascade in RAW 264.7 Cells

  Jayakumar, T., Huang, C. J., Yen, T. L., Hsia, C. W., Sheu, J. R., Bhavan, P. S., Huang, W. C., Hsieh, C. Y. & Hsia, C. H., Aug 2022, In: Molecules. 27, 16, 5143.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Activation of Nrf2 by the dengue virus causes an increase in CLEC5A, which enhances TNF-α production by mononuclear phagocytes

  Cheng, Y. L., Lin, Y. S., Chen, C. L., Tsai, T. T., Tsai, C. C., Wu, Y. W., Ou, Y. D., Chu, Y. Y., Wang, J. M., Yu, C. Y. & Lin, C. F., Aug 26 2016, In: Scientific Reports. 6, 32000.

  Research output: Contribution to journal › Article › peer-review
  36 Citations (Scopus)

• Activation of opioid μ-receptor by sinomenine in cell and mice

  Wang, M. H., Chang, C. K., Cheng, J. H., Wu, H. T., Li, Y. X. & Cheng, J. T., Oct 10 2008, In: Neuroscience Letters. 443, 3, p. 209-212 4 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• Activation of p38 MAPK-regulated Bcl-xL signaling increases survival against zoledronic acid-induced apoptosis in osteoclast precursors

  Tai, T. W., Su, F. C., Chen, C. Y., Jou, I. M. & Lin, C. F., Oct 2014, In: Bone. 67, p. 166-174 9 p.

  Research output: Contribution to journal › Article › peer-review
  30 Citations (Scopus)

• Activation of p38 mitogen-activated protein kinase in spinal microglia contributes to incision-induced mechanical allodynia

  Wen, Y-R., Suter, M. R., Ji, R. R., Yeh, G. C., Wu, Y. S., Wang, K. C., Kohno, T., Sun, W. Z. & Wang, C. C., Jan 2009, In: Anesthesiology. 110, 1, p. 155-165 11 p.

  Research output: Contribution to journal › Article › peer-review
  116 Citations (Scopus)

• Activation of p53/miR-34a tumor suppressor axis by Chinese herbal formula JP-1 in A549 lung adenocarcinoma cells

  Yao, C. J., Chow, J. M., Lin, P. C., Hu, T. S., Kuo, H. C., Huang, J. S., Bai, K. J. & Lai, G. M., 2016, In: Evidence-based Complementary and Alternative Medicine. 2016, 5989681.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Activation of peripheral TRPM8 mitigates ischemic stroke by topically applied menthol

  Huang, S. S., Su, H. H., Chien, S. Y., Chung, H. Y., Luo, S. T., Chu, Y. T., Wang, Y. H., MacDonald, I. J., Lee, H. H. & Chen, Y. H., Dec 2022, In: Journal of Neuroinflammation. 19, 1, 192.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Activation of PERK contributes to apoptosis and G2/M arrest by microtubule disruptors in human colorectal carcinoma cells

  Wu, M. S., Chien, C. C., Jargalsaikhan, G., Ilsan, N. A. & Chen, Y. C., Jan 2020, In: Cancers. 12, 1, 97.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  8 Citations (Scopus)

• Activation of PERK in ET-1- and thrombin-induced pulmonary fibroblast differentiation: Inhibitory effects of curcumin

  Chen, Y. C., Chen, B. C., Huang, H. M., Lin, S. H. & Lin, C-H., Sept 2019, In: Journal of Cellular Physiology. 234, 9, p. 15977-15988 12 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Activation of phosphodiesterase IV during desensitization of the A(2A) adenosine receptor-mediated cyclic AMP response in rat pheochromocytoma (PC12) cells

  Chang, Y. H., Conti, M., Lee, Y. C., Lai, H. L., Ching, Y. H. & Chern, Y., Sept 1997, In: Journal of Neurochemistry. 69, 3, p. 1300-1309 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  26 Citations (Scopus)

• Activation of PPAR-α induces cell cycle arrest and inhibits transforming growth factor-β1 induction of smooth muscle cell phenotype in 10T1/2 mesenchymal cells

  Lien, S. C., Wei, S. Y., Chang, S. F., Chang, M. D. T., Chang, J. Y. & Chiu, J. J., May 1 2013, In: Cellular Signalling. 25, 5, p. 1252-1263 12 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• Activation of ROS/NF-κB and Ca²⁺/CaM kinase II are necessary for VCAM-1 induction in IL-1β-treated human tracheal smooth muscle cells

  Luo, S. F., Chang, C. C., Lee, I-T., Lee, C. W., Lin, W. N., Lin, C. C. & Yang, C. M., May 15 2009, In: Toxicology and Applied Pharmacology. 237, 1, p. 8-21 14 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• Activation of Sp1-mediated transcription by Rta of Epstein-Barr virus via an interaction with MCAF1

  Chang, L. K., Chung, J. Y., Hong, Y. R., Ichimura, T., Nakao, M. & Liu, S. T., 2005, In: Nucleic Acids Research. 33, 20, p. 6528-6539 12 p.

  Research output: Contribution to journal › Article › peer-review
  60 Citations (Scopus)

• Activation of telomerase and cyclooxygenase-2 in PDGF and FGF inhibition of C₂-ceramide-induced apoptosis

  Chien, C. C., Shen, S. C., Yang, L. Y., Wu, C. Y., Liau, J. S. & Chen, Y. C., Feb 2009, In: Journal of Cellular Physiology. 218, 2, p. 405-415 11 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Activation of the calcineurin-nuclear factor of activated T-cell signal transduction pathway in atrial fibrillation

  Lin, C. C., Lin, J. L., Lin, C. S., Tsai, M. C., Su, M. J., Lai, L. P. & Stephen Huang, S. K., Jan 1 2004, In: Chest. 126, 6, p. 1926-1932 7 p.

  Research output: Contribution to journal › Article › peer-review
  38 Citations (Scopus)

• Activation of the cellular oncogene c-erbB by ltr insertion: Molecular basis for induction of erythroblastosis by avian leukosis virus

  Fung, Y. K. T., Lewis, W. G., Crittenden, L. B. & Kung, H. J., Jan 1 1983, In: Cell. 33, 2, p. 357-368 12 p.

  Research output: Contribution to journal › Article › peer-review
  139 Citations (Scopus)

• Activation of the iberiotoxin-sensitive BK_Ca channels by salvianolic acid B of the porcine coronary artery smooth muscle cells

  Lam, F. F. Y., Seto, S. W., Kwan, Y. W., Yeung, J. H. K. & Chan, P., Sept 28 2006, In: European Journal of Pharmacology. 546, 1-3, p. 28-35 8 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• Activation of the monocytic α7 nicotinic acetylcholine receptor modulates oxidative stress and inflammation-associated development of coronary artery spasm via a p38 MAP-kinase signaling-dependent pathway

  Hung, M-Y., Wu, Y-H., Bamodu, O. A., Chen, X., Lin, Y-K., Hu, P., Chang, N-C., Pang, J-H. S. & Yeh, C-T., May 20 2018, In: Free Radical Biology and Medicine. 120, p. 266-276 11 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Activation of the NLRP3 and AIM2 inflammasomes in a mouse model of Schistosoma mansoni infection

  Chen, T. T. W., Cheng, P. C., Chang, K. C., Cao, J. P., Feng, J. L., Chen, C. C., Lam, H. Y. P. & Peng, S. Y., Jan 1 2020, In: Journal of Helminthology. 94, e72.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• Activation of the Notch1/STAT3/Twist signaling axis promotes gastric cancer progression

  Hsu, K. W., Hsieh, R. H., Huang, K. H., Li, A. F. Y., Chi, C. W., Wang, T. Y., Tseng, M. J., Wu, K. J. & Tsai, T-S., Aug 2012, In: Carcinogenesis. 33, 8, p. 1459-1467 9 p.

  Research output: Contribution to journal › Article › peer-review
  104 Citations (Scopus)

• Activation of the renin-angiotensin system in hyperoxia-induced lung fibrosis in neonatal rats

  Jiang, J. S., Lang, Y. D., Chou, H-C., Shih, C-M., Wu, M. Y., Chen, C-M. & Wang, L-F., Dec 2011, In: Neonatology. 101, 1, p. 47-54 8 p.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• Activation of thromboxane receptor α induces expression of cyclooxygenase-2 through multiple signaling pathways in A549 human lung adenocarcinoma cells

  Wei, J., Yan, W., Li, X., Chang, W. C. & Tai, H. H., Sept 1 2007, In: Biochemical Pharmacology. 74, 5, p. 787-800 14 p.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress

  Li, T. K., Chen, A. Y., Yu, C., Mao, Y., Wang, H. & Liu, L-F., Jun 15 1999, In: Genes and Development. 13, 12, p. 1553-1560 8 p.

  Research output: Contribution to journal › Article › peer-review
  148 Citations (Scopus)

• Activation of TWIST1 by COL11A1 promotes chemoresistance and inhibits apoptosis in ovarian cancer cells by modulating NF-κB-mediated IKKβ expression

  Wu, Y. H., Huang, Y. F., Chang, T. H. & Chou, C. Y., Dec 1 2017, In: International Journal of Cancer. 141, 11, p. 2305-2317 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  40 Citations (Scopus)

• Activations of TRPA1 and P2X receptors are important in ROS-Mediated stimulation of capsaicin-Sensitive lung vagal afferents by cigarette smoke in rats

  Lin, Y-S., Hsu, C-C., Bien, M-Y., Hsu, H-C., Weng, H-T. & Kou, Y-R., May 2010, In: Journal of Applied Physiology. 108, 5, p. 1293-1303 11 p.

  Research output: Contribution to journal › Article › peer-review
  46 Citations (Scopus)