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• A novel sol-gel Bi_2-xHf_xO_3+x/2 radiopacifier for mineral trioxide aggregates (MTA) as dental filling materials

  Yang, T. S., Chen, M. S., Huang, C. J., Chen, C. Y., Brangule, A., Zarkov, A., Kareiva, A., Lin, C. K. & Yang, J. C., Aug 2 2021, In: Applied Sciences (Switzerland). 11, 16, 7292.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• A novel SNP in the 5' regulatory region of organic anion transporter 1 is associated with chronic kidney disease

  Sun, C. Y., Wu, M. S., Lee, C. C., Chen, S. H., Lo, K. C. & Chen, Y. H., Dec 1 2018, In: Scientific Reports. 8, 1, 8085.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• A novel smart nanowire biosensor with hybrid sensor/memory/CMOS technology

  Chen, M. C., Chen, H. Y., Lin, C. Y., Tsai, C. M., Hsieh, C. F., Horng, J. T., Qiu, J. T., Huang, C. C. & Yang, F. L., 2010, 2010 IEEE International Electron Devices Meeting, IEDM 2010. p. 36.2.1-36.2.4 5703485. (Technical Digest - International Electron Devices Meeting, IEDM).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
  2 Citations (Scopus)

• A Novel Small-World Model: Using Social Mirror Identities for Epidemic Simulations

  Huang, C. Y., Sun, C. T., Hsieh, J. L., Chen, Y. M. A. & Lin, H., Jan 1 2005, In: Simulation. 81, 10, p. 671-699 29 p.

  Research output: Contribution to journal › Article › peer-review
  39 Citations (Scopus)

• A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase i

  Yu, C. C., Pan, S. L., Chao, S. W., Liu, S. P., Hsu, J. L., Yang, Y. C., Li, T. K., Huang, W. J. & Guh, J. H., Aug 1 2014, In: Biochemical Pharmacology. 90, 3, p. 320-330 11 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• A novel small-form NEDD4 regulates cell invasiveness and apoptosis to promote tumor metastasis

  Liao, C. J., Chi, H. C., Tsai, C. Y., Chen, D. C., Wu, S. M., Tseng, Y. H., Lin, Y. H., Chung, I. H., Chen, C. Y., Lin, S. L., Huang, S. F., Huang, Y. H. & Lin, K. H., 2015, In: Oncotarget. 6, 11, p. 9341-9354 14 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• A novel single nucleotide polymorphism in XRCC4 gene is associated with gastric cancer susceptibility in Taiwan

  Chiu, C. F., Wang, C. H., Wang, C. L., Lin, C. C., Hsu, N. Y., Weng, J. R. & Bau, D. T., Feb 2008, In: Annals of Surgical Oncology. 15, 2, p. 514-518 5 p.

  Research output: Contribution to journal › Article › peer-review
  69 Citations (Scopus)

• A novel simple phantom for verifying the dose of radiation therapy

  Lee, J. H., Chang, L. T., Shiau, A. C., Chen, C. W., Liao, Y. J., Li, W. J., Lee, M. S. & Hsu, S. M., 2015, In: BioMed Research International. 2015, 934387.

  Research output: Contribution to journal › Article › peer-review

• A novel signature of ccnf-associated e3 ligases collaborate and counter each other in breast cancer

  Chang, S. C., Hung, C. S., Zhang, B. X., Hsieh, T. H., Hsu, W. & Ding, J. L., Jun 2 2021, In: Cancers. 13, 12, 2873.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  8 Citations (Scopus)

• A Novel Selective JAK2 Inhibitor Identified Using Pharmacological Interactions

  Lin, T. E., HuangFu, W. C., Chao, M. W., Sung, T. Y., Chang, C. D., Chen, Y. Y., Hsieh, J. H., Tu, H. J., Huang, H. L., Pan, S. L. & Hsu, K. C., Dec 4 2018, In: Frontiers in Pharmacology. 9, 1379.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Citations (Scopus)

• A novel scoring system combining Modified Early Warning Score with biomarkers of monocyte distribution width, white blood cell counts, and neutrophil-to-lymphocyte ratio to improve early sepsis prediction in older adults

  Lin, S. F., Lin, H. A., Pan, Y. H. & Hou, S. K., 2022, (Accepted/In press) In: Clinical Chemistry and Laboratory Medicine.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• A novel salicylanilide derivative induces autophagy cell death in castration-resistant prostate cancer via ER stress-activated PERK signaling pathway

  Hsieh, C-L., Huang, H-S., Chen, K-C., Saka, T., Chiang, C-Y., Chung, L. W. K. & Sung, S-Y., Jan 1 2020, In: Molecular Cancer Therapeutics. 19, 1, p. 101-111 11 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• A novel ruthenium (II)-derived organometallic compound, TQ-6, potently inhibits platelet aggregation: Ex vivo and in vivo studies

  Hsia, C. H., Velusamy, M., Sheu, J. R., Khamrang, T., Jayakumar, T., Lu, W. J., Lin, K. H. & Chang, C. C., Dec 1 2017, In: Scientific Reports. 7, 1, 9556.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• A novel rotating electrochemically anodizing process to fabricate titanium oxide surface nanostructures enhancing the bioactivity of osteoblastic cells

  Chang, C. H., Lee, H. C., Chen, C. C., Wu, Y. H., Hsu, Y. M., Chang, Y. P., Yang, T. I. & Fang, H. W., Jul 1 2012, In: Journal of Biomedical Materials Research - Part A. 100 A, 7, p. 1687-1695 9 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• A novel role of thrombospondin-1 in cervical carcinogenesis: Inhibit stroma reaction by inhibiting activated fibroblasts from invading cancer

  Wu, M-P., Young, M. J., Tzeng, C. C., Tzeng, C. R., Huang, K. F., Wu, L. W. & Chou, C. Y., Jun 2008, In: Carcinogenesis. 29, 6, p. 1115-1123 9 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• A novel role of the tumor suppressor GNMT in cellular defense against DNA damage

  Wang, Y. C., Lin, W. L., Lin, Y. J., Tang, F. Y., Chen, Y. M. & Chiang, E. P. I., Feb 15 2014, In: International Journal of Cancer. 134, 4, p. 799-810 12 p.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• A novel role of sesamol in inhibiting NF-B-mediated signaling in platelet activation

  Chang, C. C., Lu, W-J., Ong, E. T., Chiang, C-W., Lin, S-C., Huang, S. Y. & Sheu, J. R., 2011, In: Journal of Biomedical Science. 18, 1, 93.

  Research output: Contribution to journal › Article › peer-review
  36 Citations (Scopus)

• A novel role of metalloproteinase in cancer-mediated immunosuppression

  Sheu, B. C., Hsu, S. M., Ho, H. N., Lien, H. C., Huang, S. C. & Lin, R. H., Jan 1 2001, In: Cancer Research. 61, 1, p. 237-242 6 p.

  Research output: Contribution to journal › Article › peer-review
  257 Citations (Scopus)

• A novel role of andrographolide, an NF-kappa B inhibitor, on inhibition of platelet activation: The pivotal mechanisms of endothelial nitric oxide synthase/cyclic GMP

  Lu, W-J., Lee, J. J., Chou, D. S., Jayakumar, T., Fong, T. H., Hsiao, G. & Sheu, J. R., Dec 2011, In: Journal of Molecular Medicine. 89, 12, p. 1261-1273 13 p.

  Research output: Contribution to journal › Article › peer-review
  75 Citations (Scopus)

• A novel role for the klebsiella pneumoniae sap (sensitivity to antimicrobial peptides) transporter in intestinal cell interactions, innate immune responses, liver abscess, and virulence

  Hsu, C. R., Chang, I. W., Hsieh, P. F., Lin, T. L., Liu, P. Y., Huang, C. H., Li, K. T. & Wang, J. T., Apr 8 2019, In: Journal of Infectious Diseases. 219, 8, p. 1294-1306 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Citations (Scopus)

• A novel role for tamoxifen in the inhibition of human platelets

  Chang, Y., Lee, J. J., Chen, W. F., Chou, D. S., Huang, S. Y. & Sheu, J. R., Feb 2011, In: Translational Research. 157, 2, p. 81-91 11 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• A novel role for Oct-2 in the lipopolysaccharide-mediated induction of resistin gene expression in RAW264.7 cells

  Lu, S. C., Chang, S. F., Chen, H. L., Chou, Y. Y., Lan, Y. H., Chuang, C. Y., Yu, W. H. & Chen, C. L., Mar 1 2007, In: Biochemical Journal. 402, 2, p. 387-395 9 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• A novel role for ATM in regulating proteasome- mediated protein degradation through suppression of the ISG15 conjugation pathway

  Wood, L. M., Sankar, S., Reed, R. E., Haas, A. L., Liu, L. F., McKinnon, P. & Desai, S. D., 2011, In: PLoS ONE. 6, 1, e16422.

  Research output: Contribution to journal › Article › peer-review
  41 Citations (Scopus)

• A novel Robotic Gait Training System (RGTS) may facilitate functional recovery after stroke: A feasibility and safety study

  Lin, L. F., Huang, S. W., Chang, K. H., Ouyang, J. H., Liou, T. H. & Lin, Y. N., 2017, In: NeuroRehabilitation. 41, 2, p. 453-461 9 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• A novel RING finger protein, Znf179, modulates cell cycle exit and neuronal differentiation of P19 embryonal carcinoma cells

  Pao, P. C., Huang, N. K., Liu, Y. W., Yeh, S. H., Lin, S. T., Hsieh, C. P., Huang, A. M., Huang, H. S., Tseng, J. T., Chang, W. C. & Lee, Y. C., Nov 2011, In: Cell Death and Differentiation. 18, 11, p. 1791-1804 14 p.

  Research output: Contribution to journal › Article › peer-review
  28 Citations (Scopus)

• A novel resorbable α-calcium sulfate hemihydrate/amorphous calcium phosphate bone substitute for dental implantation surgery

  Wu, H. D., Lee, S. Y., Poma, M., Wu, J. Y., Wang, D. C. & Yang, J. C., Apr 1 2012, In: Materials Science and Engineering C. 32, 3, p. 440-446 7 p.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• A novel relative high-density lipoprotein index to predict the structural changes in high-density lipoprotein and its ability to inhibit endothelial–mesenchymal transition

  Lin, F. Y., Lin, Y. W., Shih, C. M., Lin, S. J., Tung, Y. T., Li, C. Y., Chen, Y. H., Lin, C. Y., Tsai, Y. T. & Huang, C. Y., May 2 2021, In: International journal of molecular sciences. 22, 10, 5210.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• A novel rehabilitation approach based on inertial sensor units

  Chen, H. R., Rau, C. L. & Yu, C. H., Apr 3 2015, Proceedings - 2015 International Conference on Platform Technology and Service, PlatCon 2015. Institute of Electrical and Electronics Engineers Inc., p. 15-16 2 p. 7079619. (Proceedings - 2015 International Conference on Platform Technology and Service, PlatCon 2015).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• A novel reconfigurable gravity balancer for lower-limb rehabilitation with switchable hip/knee-only exercise

  Tseng, T. Y., Lin, Y. J., Hsu, W. C., Lin, L. F. & Kuo, C. H., Aug 1 2017, In: Journal of Mechanisms and Robotics. 9, 4, 041002.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• A Novel Quality-Control Procedure to Improve the Accuracy of Rare Variant Calling in SNP Arrays

  Sun, T. H., Shao, Y. H. J., Mao, C. L., Hung, M. N., Lo, Y. Y., Ko, T. M. & Hsiao, T. H., Oct 2021, In: Frontiers in Genetics. 12, 736390.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  2 Citations (Scopus)

• A Novel Protein, CHRONO, Functions as a Core Component of the Mammalian Circadian Clock

  Goriki, A., Hatanaka, F., Myung, J., Kim, J. K., Yoritaka, T., Tanoue, S., Abe, T., Kiyonari, H., Fujimoto, K., Kato, Y., Todo, T., Matsubara, A., Forger, D. & Takumi, T., Jan 1 2014, In: PLoS Biology. 12, 4, e1001839.

  Research output: Contribution to journal › Article › peer-review
  100 Citations (Scopus)

• A novel printhead multiplexer data registration chip system with injection cavity design

  Liou, J. C., Su, T. J., Lin, W. C. & Wen, W. J., Jan 1 2018, In: Microsystem Technologies. p. 1-6 6 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• A novel printhead multiplexer data registration chip system

  Liou, J. C., Su, T. J., Wen, W. J. & Lin, W. C., Feb 2 2017, Proceedings of the IEEE International Conference on Advanced Materials for Science and Engineering: Innovation, Science and Engineering, IEEE-ICAMSE 2016. Institute of Electrical and Electronics Engineers Inc., p. 601-604 4 p. 7840211

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
  1 Citation (Scopus)

• A novel preventive mechanism of gentamicin-induced nephrotoxicity by atorvastatin

  Lee, M. C., Cheng, K. J., Chen, S. M., Li, Y. C., Imai, K., Lee, C. M. & Lee, J. A., Nov 1 2019, In: Biomedical Chromatography. 33, 11, p. e4639 e4639.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• A novel prenylated C6-C3 compound with estrogen-like activity from the fruits of Illicium arborescens

  Liaw, C. C., Chen, Y. C., Fazary, A. E., Hsieh, J. L., Chen, S. Y., Chien, C. T., Sheu, S. Y., Kuo, Y. H., Chiang, B. L. & Shen, Y. C., 2013, In: Phytochemistry Letters. 6, 3, p. 397-402 6 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• A novel predictive score for hepatocellular carcinoma development in patients with chronic hepatitis C after sustained response to pegylated interferon and ribavirin combination therapy

  Chang, K. C., Hung, C. H., Lu, S. N., Wang, J. H., Lee, C. M., Chen, C. H., Yen, M. F., Lin, S. C., Yen, Y. H., Tsai, M. C., Tseng, P. L. & Hu, T. H., Nov 2012, In: Journal of Antimicrobial Chemotherapy. 67, 11, p. 2766-2772 7 p., dks269.

  Research output: Contribution to journal › Article › peer-review
  70 Citations (Scopus)

• A novel postoperative seizure classification for long-term mortality of patients with intractable epilepsy: Comparison with the engel system

  Shih, Y. H., Yen, A. M. F., Yen, D. J., Hung, L. P., Chen, H. H. & Liou, H. H., Jul 2011, In: Neurosurgery. 69, 1, p. 64-70 7 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• A novel porcine graft for regeneration of bone defects

  Salamanca, E., Lee, W. F., Lin, C. Y., Huang, H. M., Lin, C. T., Feng, S-W. & Chang, W. J., 2015, In: Materials. 8, 5, p. 2523-2536 14 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• A novel porcine collagen GTR membrane for treatment of Class II molar furcation involvement

  Hsu, C. J., Lin, S. L., Chang, W. J., Salamanca, E., Feng, S-W., Teng, N. C. & Huang, H. M., May 1 2014, In: Journal of Polymer Engineering. 34, 3, p. 237-240 4 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• A novel podophyllotoxin-derived compound GL331 is more potent than its congener VP-16 in killing refractory cancer cells

  Huang, T. S., Lee, C. C., Chao, Y., Shu, C. H., Chen, L. T., Chen, L. L., Chen, M. H., Yuan, C. C. & Whang-Peng, J., Jan 1 1999, In: Pharmaceutical Research. 16, 7, p. 997-1002 6 p.

  Research output: Contribution to journal › Article › peer-review
  63 Citations (Scopus)

• A novel phycobiliprotein alleviates allergic airway inflammation by modulating immune responses

  Chang, C. J., Yang, Y. H., Liang, Y. C., Chiu, C. J., Chu, K. H., Chou, H. N. & Chiang, B. L., Jan 1 2011, In: American Journal of Respiratory and Critical Care Medicine. 183, 1, p. 15-25 11 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• A novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery

  Chen, S. C., Wu, Y. C., Mi, F. L., Lin, Y. H., Yu, L. C. & Sung, H. W., Apr 28 2004, In: Journal of Controlled Release. 96, 2, p. 285-300 16 p.

  Research output: Contribution to journal › Article › peer-review
  781 Citations (Scopus)

• A novel peroxisome proliferator-activated receptor α/γ agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells

  Kao, Y. H., Hsieh, H. P., Chitlimalla, S. K., Pan, W. Y., Kuo, C. C., Tsai, Y. C., Lin, W. H., Chuang, S. E. & Chang, J. Y., Feb 2008, In: Anti-Cancer Drugs. 19, 2, p. 151-158 8 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• A Novel PD-L1-targeting Antagonistic DNA Aptamer With Antitumor Effects

  Lai, W. Y., Huang, B. T., Wang, J. W., Lin, P. Y. & Yang, P. C., 2016, In: Molecular Therapy - Nucleic Acids. 5, p. e397

  Research output: Contribution to journal › Article › peer-review

  Open Access
  71 Citations (Scopus)

• A novel p53 mutant retained functional activity in lung carcinomas

  Ko, J. L., Chiao, M. C., Chang, S. L., Lin, P., Lin, J. C., Sheu, G. T. & Lee, H., Sep 4 2002, In: DNA Repair. 1, 9, p. 755-762 8 p.

  Research output: Contribution to journal › Article › peer-review
  21 Citations (Scopus)

• A novel organ culture model of a joint for the evaluation of static and dynamic load on articular cartilage

  Lin, Y. C., Hall, A. C. & Simpson, A. H. R. W., Mar 1 2018, In: Bone and Joint Research. 7, 3, p. 205-212 8 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• A novel oral indoline-sulfonamide agent, N-[1-(4-methoxybenzenesulfonyl)-2, 3-dihydro-1H-indol-7-yl]-isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule

  Liou, J. P., Hsu, K. S., Kuo, C. C., Chang, C. Y. & Chang, J. Y., Oct 2007, In: Journal of Pharmacology and Experimental Therapeutics. 323, 1, p. 398-405 8 p.

  Research output: Contribution to journal › Article › peer-review
  62 Citations (Scopus)

• A novel optoelectronic switch array for communication network

  Liou, J. C., Jan 2013, Communication Technologies: Societal Perspectives, Strategic Management and Impact on Business. Nova Science Publishers, Inc., p. 83-106 24 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• A novel optical technique for measuring 5-axis surface movement

  Zhao, W., Wu, J. & Beck, T., Dec 1 2004, In: Proceedings of SPIE - The International Society for Optical Engineering. 5606, p. 66-73 8 p., 12.

  Research output: Contribution to journal › Conference article › peer-review
  4 Citations (Scopus)

• A novel one-pot synthesis and characterization of silk fibroin/α-calcium sulfate hemihydrate for bone regeneration

  Pandey, A., Yang, T. S., Cheng, S. L., Huang, C. S., Brangule, A., Kareiva, A. & Yang, J. C., Jun 2 2021, In: Polymers. 13, 12, 1996.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)