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• 2021

  PKCδ mediates mitochondrial ROS generation and oxidation of HSP60 to relieve RKIP inhibition on MAPK pathway for HCC progression

  Mandal, J. P., Shiue, C. N., Chen, Y. C., Lee, M. C., Yang, H. H., Chang, H. H., Hu, C. T., Liao, P. C., Hui, L. C., You, R. I. & Wu, W. S., Feb 1 2021, In: Free Radical Biology and Medicine. 163, p. 69-87 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Citations (Scopus)

• PLA2G6 mutations cause motor dysfunction phenotypes of young-onset dystonia–parkinsonism type 14 and can be relieved by DHA treatment in animal models

  Yeh, T. H., Liu, H. F., Chiu, C. C., Cheng, M. L., Huang, G. J., Huang, Y. C., Liu, Y. C., Huang, Y. Z., Lu, C. S., Chen, Y. C., Chen, H. Y. & Cheng, Y. C., Dec 2021, In: Experimental Neurology. 346, 113863.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Plasma 25(Oh)d concentrations and gestational diabetes mellitus among pregnant women in taiwan

  Pham, T. T. M., Huang, Y. L., Chao, J. C. J., Chang, J. S., Chen, Y. C., Wang, F. F. & Bai, C. H., Aug 2021, In: Nutrients. 13, 8, 2538.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Plasma d-glutamate levels for detecting mild cognitive impairment and Alzheimer’s disease: Machine learning approaches

  Chang, C. H., Lin, C. H., Liu, C. Y., Huang, C. S., Chen, S. J., Lin, W. C., Yang, H. T. & Lane, H. Y., Mar 2021, In: Journal of Psychopharmacology. 35, 3, p. 265-272 8 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• Plasma extracellular vesicles tau and β-amyloid as biomarkers of cognitive dysfunction of Parkinson's disease

  Chung, C. C., Chan, L., Chen, J. H., Bamodu, O. A., Chiu, H. W. & Hong, C. T., Oct 2021, In: FASEB Journal. 35, 10, e21895.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Plasma extracellular vesicle α-synuclein level in patients with parkinson’s disease

  Chung, C. C., Chan, L., Chen, J. H., Hung, Y. C. & Hong, C. T., May 2021, In: Biomolecules. 11, 5, 744.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Plasma vitamin B₁₂ and folate alter the association of blood lead and cadmium and total urinary arsenic levels with chronic kidney disease in a Taiwanese population

  Hsueh, Y. M., Huang, Y. L., Lin, Y. F., Shiue, H. S., Lin, Y. C. & Chen, H. H., Nov 2021, In: Nutrients. 13, 11, 3841.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Plasmonic gold nanoisland film for bacterial theranostics

  Tan, S. H., Yougbaré, S., Tao, H. Y., Chang, C. C. & Kuo, T. R., Nov 2021, In: Nanomaterials. 11, 11, 3139.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Citations (Scopus)

• Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism

  Lee, T. Y., Lu, W. J., Changou, C. A., Hsiung, Y. C., Trang, N. T. T., Lee, C. Y., Chang, T. H., Jayakumar, T., Hsieh, C. Y., Yang, C. H., Chang, C. C., Chen, R. J., Sheu, J. R. & Lin, K. H., Apr 2021, In: Autophagy. 17, 12, p. 1-18 18 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Platelet‐derived biomaterials exert chondroprotective and chondroregenerative effects on diabetes mellitus‐induced intervertebral disc degeneration

  Lo, W. C., Chang, C. C., Chan, C. H., Singh, A. K., Deng, Y. H., Lin, C. Y., Tsao, W., Chien, S. T., Lin, C. H. & Deng, W. P., Oct 2021, In: Life. 11, 10, 1054.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Platelet-Derived Biomaterials Inhibit Nicotine-Induced Intervertebral Disc Degeneration Through Regulating IGF-1/AKT/IRS-1 Signaling Axis

  Lo, W. C., Chiou, C. S., Tsai, F. C., Chan, C. H., Mao, S., Deng, Y. H., Wu, C. Y., Peng, B. Y. & Deng, W. P., 2021, In: Cell Transplantation. 30

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Platelet-derived biomaterials-mediated improvement of bone injury through migratory ability of embryonic fibroblasts: In vitro and in vivo evidence

  Chou, Y. R., Lo, W. C., Dubey, N. K., Lu, J. H., Liu, H. Y., Tsai, C. Y., Deng, Y. H., Wu, C. M., Huang, M. S. & Deng, W. P., Feb 15 2021, In: Aging. 13, 3, p. 3605-3617 13 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Platelet-derived growth factor receptor-α subunit targeting suppresses metastasis in advanced thyroid cancer in vitro and in vivo

  Lin, C. L., Tsai, M. L., Chen, Y. H., Liu, W. N., Lin, C. Y., Hsu, K. W., Huang, C. Y., Chang, Y. J., Wei, P. L., Chen, S. H., Huang, L. C. & Lee, C. H., Sep 2021, In: Biomolecules and Therapeutics. 29, 5, p. 551-561 11 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Platonin, a cyanine photosensitizing dye, ameliorates inflammatory responses in vascular smooth muscle cells by modulating inflammatory transcription factors

  Chiu, C. W., Yang, C. H., Tsai, J. H., Hsieh, C. Y. & Huang, S. Y., Feb 1 2021, In: Applied Sciences (Switzerland). 11, 3, p. 1-13 13 p., 1130.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Platycodin D reverses histone deacetylase inhibitor resistance in hepatocellular carcinoma cells by repressing ERK1/2-mediated cofilin-1 phosphorylation

  Hsu, W. C., Ramesh, S., Shibu, M. A., Chen, M. C., Wang, T. F., Day, C. H., Chen, R. J., Padma, V. V., Li, C. C., Tseng, Y. C. & Huang, C. Y., Feb 2021, In: Phytomedicine. 82, 153442.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• PM2.5 facilitates IL-6 production in human osteoarthritis synovial fibroblasts via ASK1 activation

  Liu, J. F., Chi, M. C., Lin, C. Y., Lee, C. W., Chang, T. M., Han, C. K., Huang, Y. L., Fong, Y. C., Chen, H. T. & Tang, C. H., Mar 2021, In: Journal of Cellular Physiology. 236, 3, p. 2205-2213 9 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• Pneumocystis jirovecii pneumonia in autoimmune rheumatic diseases: a nationwide population-based study

  Hsu, H. C., Chang, Y. S., Hou, T. Y., Chen, L. F., Hu, L. F., Lin, T. M., Chiou, C. S., Tsai, K. L., Lin, S. H., Kuo, P. I., Chen, W. S., Lin, Y. C., Chen, J. H. & Chang, C. C., 2021, (Accepted/In press) In: Clinical Rheumatology. 40, 9, p. 3755-3763 9 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Point-of-Care Ultrasound for Posterior Shoulder Dislocation: A Better Standard than X-Ray?

  Huang, W. C., Chu, K. C. W. & Hsu, Y. P., Mar 1 2021, In: Southern Medical Journal. 114, 3, p. 192 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  1 Citation (Scopus)

• Point-of-Care Ultrasound May Reduce Misdiagnosis of Pediatric Intussusception

  Hsiao, H. J., Wang, C. J., Lee, C. C., Hsin, Y. C., Yau, S. Y., Chen, S. Y., Lo, W. C., Wu, P. W., Chen, C. L. & Chang, Y. J., Feb 4 2021, In: Frontiers in Pediatrics. 9, 601492.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Polarization of type 1 macrophages is associated with the severity of viral encephalitis caused by japanese encephalitis virus and dengue virus

  Jhan, M. K., Chen, C. L., Shen, T. J., Tseng, P. C., Wang, Y. T., Satria, R. D., Yu, C. Y. & Lin, C. F., Nov 2021, In: Cells. 10, 11, 3181.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Pollen-Mimetic Metal-Organic Frameworks with Tunable Spike-Like Nanostructures That Promote Cell Interactions to Improve Antigen-Specific Humoral Immunity

  Chen, P. M., Pan, W. Y., Luo, P. K., Phung, H. N., Liu, Y. M., Chiang, M. C., Chang, W. A., Tien, T. L., Huang, C. Y., Wu, W. W., Chia, W. T. & Sung, H. W., 2021, (Accepted/In press) In: ACS Nano. 15, 4, p. 7596-7607 12 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Poloxamer 188 Attenuates Ischemia-Reperfusion-Induced Lung Injury by Maintaining Cell Membrane Integrity and Inhibiting Multiple Signaling Pathways

  Tang, S. E., Liao, W. I., Pao, H. P., Hsu, C. W., Wu, S. Y., Huang, K. L. & Chu, S. J., Jul 15 2021, In: Frontiers in Pharmacology. 12, 650573.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Polygenic panels predicting the susceptibility of multiple upper aerodigestive tract cancer in oral cancer patients

  Chien, H. T., Yeh, C. C., Young, C. K., Chen, T. P., Liao, C. T., Wang, H. M., Cho, K. L. & Huang, S. F., May 2021, In: Journal of Personalized Medicine. 11, 5, 425.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Polygenic Risk Score of Adolescent Idiopathic Scoliosis for Potential Clinical Use

  Otomo, N., Lu, H. F., Koido, M., Kou, I., Takeda, K., Momozawa, Y., Kubo, M., Kamatani, Y., Ogura, Y., Takahashi, Y., Nakajima, M., Minami, S., Uno, K., Kawakami, N., Ito, M., Sato, T., Watanabe, K., Kaito, T., Yanagida, H., Taneichi, H., & 30 othersHarimaya, K., Taniguchi, Y., Shigematsu, H., Iida, T., Demura, S., Sugawara, R., Fujita, N., Yagi, M., Okada, E., Hosogane, N., Kono, K., Nakamura, M., Chiba, K., Kotani, T., Sakuma, T., Akazawa, T., Suzuki, T., Nishida, K., Kakutani, K., Tsuji, T., Sudo, H., Iwata, A., Kaneko, K., Inami, S., Kochi, Y., Chang, W. C., Matsumoto, M., Watanabe, K., Ikegawa, S. & Terao, C., Aug 2021, In: Journal of Bone and Mineral Research. 36, 8, p. 1481-1491 11 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Polyketides with Anti-neuroinflammatory Activity fromTheissenia cinerea

  Hsieh, M. H., Hsiao, G., Chang, C. H., Yang, Y. L., Ju, Y. M., Kuo, Y. H. & Lee, T. H., Jul 23 2021, In: Journal of Natural Products. 84, 7, p. 1898-1903 6 p.

  Research output: Contribution to journal › Review article › peer-review
  5 Citations (Scopus)

• Pomelo fruit wastes are potentially valuable antioxidants, anti-inflammatories, antihypertensives, and antihyperglycemics

  Lin, L. Y., Huang, C. Y., Chen, K. C. & Peng, R. Y., 2021, (Accepted/In press) In: Horticulture Environment and Biotechnology.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Poorer exercise accommodation of regional systolic myocardial motion after spironolactone treatment in heart failure patients with preserved ejection fraction and ventricular dyssynchrony

  Yu, C. C., Chiu, F. C., Tsai, C. T., Wang, Y. C., Lai, L. P., Hwang, J. J. & Lin, J. L., Sep 1 2021, In: Journal of Clinical Medicine. 10, 17, 3827.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Population-based study on the all-cause and cause-specific risks of mortality among long-term opioid analgesics users without cancer in Taiwan

  Lee, P. F., Li, C. Y., Liu, Y. C., Chiu, C. T. & Hou, W. H., Nov 2021, In: Healthcare (Switzerland). 9, 11, 1402.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Porphyromonas gingivalis induces proinflammatory cytokine expression leading to apoptotic death through the oxidative stress/nf‐κb pathway in brain endothelial cells

  Charoensaensuk, V., Chen, Y. C., Lin, Y. H., Ou, K. L., Yang, L. Y. & Lu, D. Y., Nov 2021, In: Cells. 10, 11, 3033.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Positive Association of Serum Adiponectin Level With the Vascular Reactivity Index in Kidney Transplant Patients

  Lin, W. C., Lee, M. C. & Hsu, B. G., Dec 2021, In: Experimental and Clinical Transplantation. 19, 12, p. 1271-1276 6 p.

  Research output: Contribution to journal › Article › peer-review

• Possible interplay between estrogen and the BAFF may modify thyroid activity in Graves’ disease

  Cheng, C. W., Fang, W. F., Tang, K. T. & Lin, J. D., Dec 2021, In: Scientific Reports. 11, 1, 21350.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Post-cardiac arrest care and targeted temperature management: A consensus of scientific statement from the Taiwan Society of Emergency & Critical Care Medicine, Taiwan Society of Critical Care Medicine and Taiwan Society of Emergency Medicine

  Chiu, W. T., Lin, K. C., Tsai, M. S., Hsu, C. H., Wang, C. H., Kuo, L. K., Chien, Y. S., Wu, C. H., Lai, C. H., Huang, W. C., Wang, C. H., Wang, T. L., Hsu, H. H., Lin, J. J., Hwang, J. J., Ng, C. J., Choi, W. M. & Huang, C. H., Jan 2021, In: Journal of the Formosan Medical Association. 120, 1P3, p. 569-587 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  10 Citations (Scopus)

• Postdiagnosis Aspirin Use Associated With Decreased Biliary Tract Cancer–Specific Mortality in a Large Nationwide Cohort

  Liao, S. F., Koshiol, J., Huang, Y. H., Jackson, S. S., Huang, Y. H., Chan, C., Huang, C., Liu, P. C., Chen, Y. J., Hsieh, R. J., Huang, C. P., Lu, S. N., Chen, C. J., Shen, C. Y. & Lee, M. H., Oct 2021, In: Hepatology. 74, 4, p. 1994-2006 13 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Posterior circulation acute stroke prognosis early CT scores in predicting functional outcomes: A meta-analysis

  Lu, W. Z., Lin, H. A., Bai, C. H. & Lin, S. F., Feb 2021, In: PLoS ONE. 16, 2 February, e0246906.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Postoperative adjuvant dose-dense chemotherapy with bevacizumab and maintenance bevacizumab after neoadjuvant chemotherapy for advanced ovarian cancer: A phase II AGOG/TGOG trial

  Chou, H. H., Chen, W. C., Yang, L. Y., Huang, H. J., Chang, W. Y., Lin, H., Wu, R. C., Chen, M. Y., Qiu, J. T., Huang, K. G., Chao, A., Chang, T. C. & Lai, C. H., Jul 2021, In: European Journal of Obstetrics and Gynecology and Reproductive Biology. 262, p. 13-20 8 p.

  Research output: Contribution to journal › Article › peer-review

• Postoperative Delirium in Older Patients: A Systematic Review of Assessment and Incidence of Postoperative Delirium

  Ho, M. H., Nealon, J., Igwe, E., Traynor, V., Chang, H. C., Chen, K. H. & Montayre, J., Oct 2021, In: Worldviews on Evidence-Based Nursing. 18, 5, p. 290-301 12 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Postpartum ovarian vein thrombophlebitis presenting as vaginal bleeding: A case report

  Chiang, T. L., Chang, C. Y. & Ong, J. R., Feb 26 2021, In: Medicine. 100, 8, p. e24632

  Research output: Contribution to journal › Article › peer-review

• Posttraumatic Stress Disorder and the Associated Risk of Autoimmune Skin Diseases: A Nationwide Population-Based Cohort Study

  Dai, Y. X., Tai, Y. H., Chang, Y. T., Chen, T. J. & Chen, M. H., Apr 1 2021, In: Psychosomatic Medicine. 83, 3, p. 212-217 6 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Post-traumatic stress disorder in an adolescent with asperger syndrome

  Lin, I. C., Tseng, L. Y. & Lee, Y. T., 2021, In: Psychiatria Danubina. 32, 3-4, p. 436-437 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Post-traumatic stress disorder in Chinese teachers during covid-19 pandemic: Roles of fear of COVID-19, nomophobia, and psychological distress

  Kukreti, S., Ahorsu, D. K., Strong, C., Chen, I. H., Lin, C. Y., Ko, N. Y., Griffiths, M. D., Chen, Y. P., Kuo, Y. J. & Pakpour, A. H., Oct 2021, In: Healthcare (Switzerland). 9, 10, 1288.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  18 Citations (Scopus)

• Potent and orally active purine-based fetal hemoglobin inducers for treating β-thalassemia and sickle cell disease

  Lai, Z. S., Yeh, T. K., Chou, Y. C., Hsu, T., Lu, C. T., Kung, F. C., Hsieh, M. Y., Lin, C. H., Chen, C. T., Shen, C-K. & Jiaang, W. T., Jan 2021, In: European Journal of Medicinal Chemistry. 209, 112938.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Potential impacts of interleukin-17a promoter polymorphisms on the egfr mutation status and progression of non-small cell lung cancer in Taiwan

  Lee, K. L., Lai, T. C., Wang, Y. C., Shih, P. C., Yang, Y. C., Tsao, T. C. Y., Liu, T. C., Wen, Y. C., Chang, L. C., Yang, S. F. & Chien, M. H., Mar 2021, In: Genes. 12, 3, 427.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• Potentially inappropriate medication use among stroke residents of a long-term care facility: an observational case study using the Beers Criteria

  Hsing, C. P., Lian, J. H., Lee, J. A., Fan, H. C., Chen, S. M., Lai, C. P. & Tsai, Y. H., Aug 2021, In: Taiwan Journal of Public Health. 40, 4, p. 429-440 12 p.

  Research output: Contribution to journal › Article › peer-review

• Potential prognostic biomarkers of nima (Never in mitosis, gene a)-related kinase (nek) family members in breast cancer

  Anuraga, G., Wang, W. J., Phan, N. N., Ton, N. T. A., Ta, H. D. K., Prayugo, F. B., Xuan, D. T. M., Ku, S. C., Wu, Y. F., Andriani, V., Athoillah, M., Lee, K. H. & Wang, C. Y., Nov 2021, In: Journal of Personalized Medicine. 11, 11, 1089.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  16 Citations (Scopus)

• Potential prognostic biomarkers of OSBPL family genes in patients with pancreatic ductal adenocarcinoma

  Chou, C. W., Hsieh, Y. H., Ku, S. C., Shen, W. J., Anuraga, G., Ta, H. D. K., Lee, K. H., Lee, Y. C., Lin, C. H., Wang, C. Y. & Wang, W. J., Nov 2021, In: Biomedicines. 9, 11, 1601.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Citations (Scopus)

• Potential protection effect of er homeostasis of n⁶-(2-hydroxyethyl)adenosine isolated from cordyceps cicadae in nonsteroidal anti-inflammatory drug-stimulated human proximal tubular cells

  Chyau, C. C., Wu, H. L., Peng, C. C., Huang, S. H., Chen, C. C., Chen, C. H. & Peng, R. Y., Feb 2021, In: International journal of molecular sciences. 22, 4, p. 1-17 17 p., 1577.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  8 Citations (Scopus)

• Potential therapeutic and prognostic values of lsm family genes in breast cancer

  Ta, H. D. K., Wang, W. J., Phan, N. N., Ton, N. T. A., Anuraga, G., Ku, S. C., Wu, Y. F., Wang, C. Y. & Lee, K. H., Oct 1 2021, In: Cancers. 13, 19, 4902.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  14 Citations (Scopus)

• Potential therapies targeting metabolic pathways in cancer stem cells

  Shen, Y. A., Chen, C. C., Chen, B. J., Wu, Y. T., Juan, J. R., Chen, L. Y., Teng, Y. C. & Wei, Y. H., Jul 2021, In: Cells. 10, 7, 1772.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Citations (Scopus)

• Potent sialic acid inhibitors that target influenza A virus hemagglutinin

  Chang, Y. J., Yeh, C. Y., Cheng, J. C., Huang, Y. Q., Hsu, K. C., Lin, Y. F. & Lu, C. H., Dec 2021, In: Scientific Reports. 11, 1, 8637.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Pragmatic recruitment of memantine as the capping group for the design of HDAC inhibitors: A preliminary attempt to unravel the enigma of glioblastoma

  Nepali, K., Hsu, T. I., Hsieh, C. M., Lo, W. L., Lai, M. J., Hsu, K. C., Lin, T. E., Chuang, J. Y. & Liou, J. P., May 5 2021, In: European Journal of Medicinal Chemistry. 217, 113338.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)