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¿es el yo simplemente la recompensa?

Translated title of the contribution: Is our self nothing but reward?Northoff, G. & Hayes, D. J., Dec 2012, In : Psiquiatria Biologica. 19, SUPPL.1, p. 42-48 7 p.

Research output: Contribution to journalArticle

Reward
Ventral Tegmental Area
Neurosciences
Prefrontal Cortex
Psychology
21 Citations (Scopus)

(-)-Epigallocatechin-3-gallate decreases the impairment in learning and memory in spontaneous hypertension rats

Wang, M. H., Chang, W. J., Soung, H. S. & Chang, K. C., Dec 2012, In : Behavioural Pharmacology. 23, 8, p. 771-780 10 p.

Research output: Contribution to journalArticle

Learning
Hypertension
Locomotion
Therapeutic Uses
epigallocatechin gallate
13 Citations (Scopus)

(-)Epigallocatechin-3-gallate decreases the stress-induced impairment of learning and memory in rats

Soung, H. S., Wang, M. H., Tseng, H. C., Fang, H. W. & Chang, K. C., Aug 8 2015, In : Neuroscience Letters. 602, p. 27-32 6 p.

Research output: Contribution to journalArticle

Learning
Tea
Locomotion
Catechin
Therapeutic Uses
26 Citations (Scopus)
Catechin
Tea
Cerebral Cortex
Protein Kinase C
Glutamic Acid
25 Citations (Scopus)

(-)-Menthol inhibits WEHI-3 leukemia cells in vitro and in vivo

Lu, H. F., Liu, J. Y., Hsueh, S. C., Yang, Y. Y., Yang, J. S., Tan, T. W., Kok, L. F., Lu, C. C., Lan, S. H., Wu, S. Y., Liao, S. S., Ip, S. W. & Chung, J. G., Mar 2007, In : In Vivo. 21, 2, p. 285-289 5 p.

Research output: Contribution to journalArticle

Menthol
Leukemia
Mouthwashes
Toothpastes
Macrophages
9 Citations (Scopus)

(−)-Phenserine inhibits neuronal apoptosis following ischemia/reperfusion injury

Chang, C. F., Lai, J. H., Wu, J. C. C., Greig, N. H., Becker, R. E., Luo, Y., Chen, Y. H., Kang, S. J., Chiang, Y. H. & Chen, K. Y., Dec 15 2017, In : Brain Research. 1677, p. 118-128 11 p.

Research output: Contribution to journalArticle

Reperfusion Injury
Apoptosis
Middle Cerebral Artery Infarction
Acetylcholinesterase
Stroke
16 Citations (Scopus)

(2R,6R)-hydroxynorketamine rescues chronic stress-induced depression-like behavior through its actions in the midbrain periaqueductal gray

Chou, D., Peng, H. Y., Lin, T. B., Lai, C. Y., Hsieh, M. C., Wen, Y. C., Lee, A. S., Wang, H. H., Yang, P. S., Chen, G. D. & Ho, Y. C., Sep 1 2018, In : Neuropharmacology. 139, p. 1-12 12 p.

Research output: Contribution to journalArticle

Periaqueductal Gray
Mesencephalon
Antidepressive Agents
Depression
AMPA Receptors
7 Citations (Scopus)

(4R,6S)-2-Dihydromenisdaurilide is a Butenolide that Efficiently Inhibits Hepatitis C Virus Entry

Chung, C. Y., Liu, C. H., Wang, G. H., Jassey, A., Li, C. L., Chen, L., Yen, M. H., Lin, C. C. & Lin, L. T., Jul 18 2016, In : Scientific Reports. 6

Research output: Contribution to journalArticle

Virus Internalization
Hepacivirus
Antiviral Agents
Virus Diseases
butenolide
82 Citations (Scopus)

(Ba,Sr)Y2Si2Al2O2N 5:Eu2+: A novel near-ultraviolet converting green phosphor for white light-emitting diodes

Liu, W. R., Yeh, C. W., Huang, C. H., Lin, C. C., Chiu, Y. C., Yeh, Y. T. & Liu, R. S., Mar 21 2011, In : Journal of Materials Chemistry. 21, 11, p. 3740-3744 5 p.

Research output: Contribution to journalArticle

Phosphors
Light emitting diodes
Color
Solid state reactions
Electron energy levels
26 Citations (Scopus)

(D) Routes of delivery: Case studies. (7) Ocular delivery of peptide and protein drugs

Harris, D., Jia-Horng Liaw, L. & Robinson, J. R., Jan 1 1992, In : Advanced Drug Delivery Reviews. 8, 2-3, p. 331-339 9 p.

Research output: Contribution to journalReview article

Peptides
Pharmaceutical Preparations
Permeability
Proteins
Cytochalasin B
83 Citations (Scopus)

(G2019S) LRRK2 activates MKK4-JNK pathway and causes degeneration of SN dopaminergic neurons in a transgenic mouse model of PD

Chen, C. Y., Weng, Y. H., Chien, K. Y., Lin, J. K., Yeh, T. H., Cheng, Y. P., Lu, C. S. & Wang, H. L., Oct 2012, In : Cell Death and Differentiation. 19, 10, p. 1623-1633 11 p.

Research output: Contribution to journalArticle

MAP Kinase Kinase 2
MAP Kinase Signaling System
Dopaminergic Neurons
Leucine
Transgenic Mice
17 Citations (Scopus)

(G2019S) LRRK2 causes early-phase dysfunction of SNpc dopaminergic neurons and impairment of corticostriatal long-term depression in the PD transgenic mouse

Chou, J. S., Chen, C. Y., Chen, Y. L., Weng, Y. H., Yeh, T. H., Lu, C. S., Chang, Y. M. & Wang, H. L., 2014, In : Neurobiology of Disease. 68, p. 190-199 10 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Transgenic Mice
Corpus Striatum
Neurons
Dopamine

(Journal of Food and Drug Analysis 18, 6, (380))

Cheng, Y. W. & Lou, H. Y., Jun 2011, In : Journal of Food and Drug Analysis. 19, 2, p. 243 1 p.

Research output: Contribution to journalArticle

Food Analysis
drugs
Pharmaceutical Preparations
13 Citations (Scopus)

(N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo

Lee, H. Y., Nepali, K., Huang, F. I., Chang, C. Y., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., Feb 8 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 905-917 13 p.

Research output: Contribution to journalArticle

Quinolines
Histone Deacetylase Inhibitors
Multiple Myeloma
Growth
Hydroxamic Acids
8 Citations (Scopus)

(R1441C) LRRK2 induces the degeneration of SN dopaminergic neurons and alters the expression of genes regulating neuronal survival in a transgenic mouse model

Weng, Y. H., Chen, C. Y., Lin, K. J., Chen, Y. L., Yeh, T. H., Hsiao, I. T., Chen, I. J., Lu, C. S. & Wang, H. L., Jan 1 2016, In : Experimental Neurology. 275, p. 104-115 12 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Substantia Nigra
Leucine
Transgenic Mice
Phosphotransferases
7 Citations (Scopus)

[18F]Fluorodeoxyglucose-positron emission tomography screening for lung cancer: A systematic review and meta-analysis

Chien, C. R., Liang, J. A., Chen, J. H., Wang, H. N., Lin, C. C., Chen, C. Y., Wang, P. H., Kao, C. H. & Yeh, J. J., Dec 11 2013, In : Cancer Imaging. 13, 4, p. 458-465 8 p.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Positron-Emission Tomography
Meta-Analysis
Lung Neoplasms
Early Detection of Cancer
22 Citations (Scopus)

[21] Chemokines and chemokine receptors in model neurological pathologies: Molecular and immunocytochemical approaches

Ransohoff, R. M., Tani, M., Glabinski, A. R., Chernosky, A., Krivacic, K., Peterson, J. W., Chien, H. F. & Trapp, B. D., Jan 1 1997, In : Methods in Enzymology. 287, p. 319-348 30 p.

Research output: Contribution to journalArticle

Neurological Models
Animal Disease Models
Autoimmune Experimental Encephalomyelitis
Molecular Pathology
Chemokine Receptors
5 Citations (Scopus)

[35] Aromatic-amino acid-glyoxylate aminotransferase from rat liver

Takada, Y. & Noguchi, T., 1987, In : Methods in Enzymology. 142, C, p. 273-279 7 p.

Research output: Contribution to journalArticle

Hydroxyapatites
Microbodies
Inbred Strains Rats
Species Specificity
DEAE-Cellulose Chromatography
4 Citations (Scopus)

[5,10,15,20-Tetra-(N-methyl-3-pyridyl)porphyrin destabilizes the anti-parallel telomeric quadruplex d(TTAGGG)4].

Dutikova, I. V., Borisova, O. F., Shchelkina, A. K., Lin, J., Huang, S., Shtil', A. A. & Kaliuzhnyǐ, D. N., Sep 2010, In : Molekuliarnaia biologiia. 44, 5, p. 929-937 9 p.

Research output: Contribution to journalArticle

Porphyrins
G-Quadruplexes
Cultured Tumor Cells
Telomerase
DNA
3 Citations (Scopus)

[Expression and clinical significance of circadian gene Per2 in non-small cell lung cancer].

Chi, C., He, Z. F., Liu, Y., Lin, X. M. & Sun, C. C., Jan 1 2013, In : Chinese Journal of Oncology. 35, 2, p. 129-131 3 p.

Research output: Contribution to journalArticle

Neoplastic Gene Expression Regulation
Period Circadian Proteins
Lymphatic Metastasis
Neoplasm Grading
Neoplasm Staging
Chemical and Drug Induced Liver Injury
Inbred ICR Mouse
Tandem Repeat Sequences
Carbon Tetrachloride
Environmental Exposure
2 Citations (Scopus)

1,2,3,4,6-penta-o-galloyl-beta-D-glucopyranoside inhibits proliferation of multiple myeloma cells accompanied with suppression of MYC expression

Tseeleesuren, D., Kant, R., Yen, C. H., Hsiao, H. H. & Chen, Y. M. A., Feb 2 2018, In : Frontiers in Pharmacology. 9, FEB, 65.

Research output: Contribution to journalArticle

Rubiaceae
Multiple Myeloma
Proteasome Inhibitors
Caspase 3
Cyclin D2
27 Citations (Scopus)

1,25-Dihydroxyvitamin D3 attenuates endotoxin-induced production of inflammatory mediators by inhibiting MAPK activation in primary cortical neuron-glia cultures

Huang, Y. N., Ho, Y. J., Lai, C. C., Chiu, C. T. & Wang, J. Y., Aug 12 2015, In : Journal of Neuroinflammation. 12, 1, 147.

Research output: Contribution to journalArticle

Calcitriol
Mitogen-Activated Protein Kinases
Endotoxins
Neuroglia
Lipopolysaccharides
12 Citations (Scopus)
Connexin 43
Calcitriol
Granulosa Cells
Testosterone
Estradiol
Calcitriol
Granulosa Cells
Phosphatidylinositol 3-Kinases
Rats
Estradiol
Anthraquinones
Patents and inventions
Derivatives
Cell growth
Chemical analysis
2 Citations (Scopus)

1,4-Naphthoquinones as inhibitors of Itch, a HECT domain-E3 ligase, and tumor growth suppressors in multiple myeloma

Liu, Y. M., HuangFu, W. C., Huang, H. L., Wu, W. C., Chen, Y. L., Yen, Y., Huang, H. L., Nien, C. Y., Lai, M. J., Pan, S. L. & Liou, J. P., Nov 10 2017, In : European Journal of Medicinal Chemistry. 140, p. 84-91 8 p.

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
Multiple Myeloma
Tumors
Lead compounds
Growth

1,5-雙取代蒽醌衍生物之合成與用途

Huang, H-S. & 陳榮福, 2005

Research output: Patent

Patents and inventions
Bromine
Anthraquinones
Anti-Allergic Agents
Halogens
3 Citations (Scopus)

1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4 H -indazol-4-one: A Novel Opioid Receptor Agonist with Less Accompanying Gastrointestinal Dysfunction than Morphine

Chao, P. K., Ueng, S. H., Ou, L. C., Yeh, T. K., Chang, W. T., Chang, H. F., Chen, S. C., Tao, P. L., Law, P. Y., Loh, H. H., Cheng, M. F., Chuang, J. Y., Chen, C. T., Shih, C. & Yeh, S. H., May 1 2017, In : Anesthesiology. 126, 5, p. 952-966 15 p.

Research output: Contribution to journalArticle

Opioid Receptors
Morphine
Opioid Analgesics
Charcoal
Surgical Instruments

101菁英專案: 美國呼吸治療專業學術參訪紀要

Bien, M., Kuo, HJ., Wu, CY., Chung, JC., Chuang, T. & Shih, C-H., Apr 2008, In : 中華民國呼吸照護簡訊. 19, 1, p. 13-17 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

10-Point CT-ASPECTS-based reperfusion therapy for unknown onset stroke

Chang, C. C., Yeh, H. L., Hsiao, C. Y. & Lien, L. M., 2018, In : Journal of the Formosan Medical Association.

Research output: Contribution to journalArticle

Reperfusion
Stroke
Therapeutics
History
33 Citations (Scopus)

10 Years of experience with penile prosthesis implantation in Taiwanese patients

Chiang, H-S., Wu, C. C. & Wen, T. C., Feb 2000, In : Journal of Urology. 163, 2, p. 476-480 5 p.

Research output: Contribution to journalArticle

Penile Implantation
Patient Satisfaction
Penile Prosthesis
Equipment and Supplies
Survival
7 Citations (Scopus)

10′(Z),13′(E)-Heptadecadienylhydroquinone Inhibits Swarming and Virulence Factors and Increases Polymyxin B Susceptibility in Proteus mirabilis

Liu, M-C., Lin, S-B., Chien, H-F., Wang, W-B., Yuan, Y-H., Hsueh, P-R. & Liaw, S-J., 2012, In : PLoS One. 7, 9

Research output: Contribution to journalArticle

polymyxin B
Proteus mirabilis
Polymyxin B
swarming
Virulence Factors
46 Citations (Scopus)

11H-Isoquino[4,3-c]cinnolin-12-ones: Novel anticancer agents with potent topoisomerase I-targeting activity and cytotoxicity

Ruchelman, A. L., Singh, S. K., Ray, A., Wu, X., Yang, J. M., Zhou, N., Liu, A., Liu, L-F. & LaVoie, E. J., Feb 15 2004, In : Bioorganic and Medicinal Chemistry. 12, 4, p. 795-806 12 p.

Research output: Contribution to journalArticle

Type I DNA Topoisomerase
Cytotoxicity
Nude Mice
Antineoplastic Agents
Tumors
10 Citations (Scopus)

11-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridine derivatives as novel topoisomerase I-targeting agents

Feng, W., Satyanarayana, M., Tsai, Y. C., Liu, A. A., Liu, L. F. & LaVoie, E. J., Sep 15 2008, In : Bioorganic and Medicinal Chemistry. 16, 18, p. 8598-8606 9 p.

Research output: Contribution to journalArticle

Phenanthridines
Type I DNA Topoisomerase
Cytotoxicity
Derivatives
Tumor Cell Line
8 Citations (Scopus)

120 Hz low cross-talk stereoscopic display with intelligent LED backlight enabled by multi-dimensional controlling IC

Liou, J. C. & Tseng, F. G., Dec 2009, In : Displays. 30, 4-5, p. 148-154 7 p.

Research output: Contribution to journalArticle

Light emitting diodes
Display devices
Synchronization
Scanning
Liquid crystal displays
74 Citations (Scopus)
Extracellular Signal-Regulated MAP Kinases
Tetradecanoylphorbol Acetate
Glioblastoma
Matrix Metalloproteinases
Protein Kinase C
26 Citations (Scopus)
Tetradecanoylphorbol Acetate
HL-60 Cells
Protein Kinase C
Leukemia
Acetates
16 Citations (Scopus)

12-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridines as novel topoisomerase I-targeting antitumor agents

Feng, W., Satyanarayana, M., Tsai, Y. C., Liu, A. A., Liu, L. F. & LaVoie, E. J., Apr 1 2009, In : Bioorganic and Medicinal Chemistry. 17, 7, p. 2877-2885 9 p.

Research output: Contribution to journalArticle

Phenanthridines
Type I DNA Topoisomerase
Antineoplastic Agents
Cell growth
Growth
5 Citations (Scopus)

131I treatment for thyroid cancer and risk of developing primary hyperparathyroidism: A cohort study

Lin, C. M., Doyle, P., Tsan, Y. T., Lee, C. H., Wang, J. D. & Chen, P. C., 2014, In : European Journal of Nuclear Medicine and Molecular Imaging. 41, 2, p. 253-259 7 p.

Research output: Contribution to journalArticle

Primary Hyperparathyroidism
Thyroid Neoplasms
Cohort Studies
Therapeutics
National Health Programs
3 Citations (Scopus)

133Xenon ventilation scan as a functional assessment in bronchiectasis.

Hung, T. C., Lin, H. C., Lin, K. J. & Kuo, H. P., Jan 1 1998, In : Changgeng yi xue za zhi / Changgeng ji nian yi yuan = Chang Gung medical journal / Chang Gung Memorial Hospital. 21, 4, p. 403-408 6 p.

Research output: Contribution to journalArticle

Bronchiectasis
Ventilation
Mucus
Walking
Tomography
Dioscorea
Glucose Intolerance
dipeptides
Dipeptides
yams
22 Citations (Scopus)

13-cis-Retinoic acid induces cellular differentiation and durable remission in refractory cutaneous Ki-1 lymphoma

Chow, J. M., Cheng, A. L., Su, I. J. & Wang, C. H., 1991, In : Cancer. 67, 10, p. 2490-2494 5 p.

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
Isotretinoin
Skin
Xerostomia
Hyperlipidemias
20 Citations (Scopus)
Salvia miltiorrhiza
Prostate
Apoptosis
Carcinoma
Transcription Factor CHOP
17 Citations (Scopus)
Salvia miltiorrhiza
ribose
adenosine diphosphate
Functional Food
leukemias
17 Citations (Scopus)

15,16-dihydrotanshinone i-induced apoptosis in human colorectal cancer cells: Involvement of ATF3

Suk, F. M., Jou, W. J., Lin, R-J., Lin, S. Y., Tzeng, F. Y. & Liang, Y. C., Aug 2013, In : Anticancer Research. 33, 8, p. 3225-3232 8 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Apoptosis
Activating Transcription Factor 3
Salvia miltiorrhiza
Medicinal Plants
15 Citations (Scopus)

15-Deoxy-Δ12,14-prostaglandin J2 inhibits fibrogenic response in human hepatoma cells

Suk, F. M., Chen, C. H., Lin, S. Y., Cheng, C. J., Yen, S. J., Hung, L. F., Liu, D. Z. & Liang, Y. C., May 22 2009, In : Toxicology Letters. 187, 1, p. 22-27 6 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Peroxisome Proliferator-Activated Receptors
Connective Tissue Growth Factor
Hepatocellular Carcinoma
Phosphorylation
10 Citations (Scopus)

15-Deoxy-∆12,14-PGJ2, by Activating Peroxisome Proliferator-Activated Receptor-Gamma, Suppresses p22phox Transcription to Protect Brain Endothelial Cells Against Hypoxia-Induced Apoptosis

Wu, J. S., Tsai, H. D., Huang, C. Y., Chen, J. J. & Lin, T. N., Oct 2 2014, In : Molecular Neurobiology. 50, 1, p. 221-238 18 p.

Research output: Contribution to journalReview article

Cell Hypoxia
PPAR gamma
Endothelial Cells
Apoptosis
Reactive Oxygen Species