Find Research Outputs

2019

Specific activation of pro-Infliximab enhances selectivity and safety of rheumatoid arthritis therapy

Lu, Y. C., Chuang, C. H., Chuang, K. H., Chen, I. J., Huang, B. C., Lee, W. H., Wang, H. E., Li, J. J., Cheng, Y. A., Cheng, K. W., Wang, J. Y., Hsieh, Y. C., Lin, W. W. & Cheng, T. L., Jun 1 2019, In : PLoS Biology. 17, 6, p. e3000286

Research output: Contribution to journalArticle

Open Access
rheumatoid arthritis
Rheumatoid Arthritis
Chemical activation
Safety
therapeutics

Spherical Composite Powder by Coupling Polymethyl Methacrylate and Boron Nitride via Spray Drying for Cosmetic Application

Su, C-Y., Wang, J-C., Chen, C-Y., Chu, K. & Lin, C-K., Feb 28 2019, In : Materials. 12, 5

Research output: Contribution to journalArticle

Spray drying
Cosmetics
Boron nitride
Polymethyl Methacrylate
Polymethyl methacrylates
1 Citation (Scopus)

Spindle Cell Tumors with RET Gene Fusions Exhibit a Morphologic Spectrum Akin to Tumors with NTRK Gene Fusions

Antonescu, C. R., Dickson, B. C., Swanson, D., Zhang, L., Sung, Y. S., Kao, Y-C., Chang, W. C., Ran, L., Pappo, A., Bahrami, A., Chi, P. & Fletcher, C. D., Jan 1 2019, In : American Journal of Surgical Pathology.

Research output: Contribution to journalArticle

Gene Fusion
Neoplasms
RNA Sequence Analysis
Gene Rearrangement
Fibrosarcoma

Spontaneous Brain Activity Predicts Task-Evoked Activity During Animate Versus Inanimate Touch

Scalabrini, A., Ebisch, S. J. H., Huang, Z., Di Plinio, S., Perrucci, M. G., Romani, G. L., Mucci, C. & Northoff, G., Jan 21 2019, In : Cerebral cortex (New York, N.Y. : 1991). 18 p.

Research output: Contribution to journalArticle

Gyrus Cinguli
Touch
Prefrontal Cortex
Brain
Hand

Spray-dried nanoporous NiO/PANI:PSS composite microspheres for high-performance asymmetric supercapacitors

Cho, E. C., Chang-Jian, C. W., Lee, K. C., Huang, J. H., Ho, B. C., Ding, Y. R. & Hsiao, Y. S., Oct 15 2019, In : Composites Part B: Engineering. 175, 107066.

Research output: Contribution to journalArticle

Polyaniline
Microspheres
Sodium
Composite materials
Spray drying
4 Citations (Scopus)

Spray-drying synthesis of Li 4 Ti 5 O 12 microspheres in pilot scale using TiO 2 nanosheets as starting materials and their application in high-rate lithium ion battery

Chang-Jian, C. W., Cho, E. C., Huang, J. H., Huang, J. H., Chou, J. A., Ho, B. C., Lee, K. C. & Hsiao, Y. S., Jan 30 2019, In : Journal of Alloys and Compounds. 773, p. 376-386 11 p.

Research output: Contribution to journalArticle

Spray drying
Nanosheets
Microspheres
Solid state reactions
Energy storage

SRPX and HMCN1 regulate cancer‑associated fibroblasts to promote the invasiveness of ovarian carcinoma

Liu, C. L., Pan, H. W., Torng, P. L., Fan, M. H. & Mao, T. L., Jan 1 2019, In : Oncology Reports. 42, 6, p. 2706-2715 10 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Fibroblasts
Carcinoma
Proteins
Neoplasms
Hypoxia-Inducible Factor 1
RNA-Binding Proteins
Alternative Splicing
Lung Neoplasms
Protein Isoforms

Stability of Principal Hydrolysable Tannins from Trapa taiwanensis Hulls

Wang, C. C., Chen, H. F., Wu, J. Y. & Chen, L. G., Jan 21 2019, In : Molecules. 24, 2, 365.

Research output: Contribution to journalArticle

Open Access
Hydrolyzable Tannins
fluids
antioxidants
Fluids
buffers
1 Citation (Scopus)

Statins and the risk of bleeding in patients taking dabigatran

Ho, B. L., Lin, Y. J., Lin, S. F., Chou, P. S., Chen, C. F., Lin, R. T., Hu, H. H. & Chao, A. C., May 1 2019, In : Acta Neurologica Scandinavica. 139, 5, p. 455-461 7 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hemorrhage
Atrial Fibrillation
Stroke
Secondary Prevention
2 Citations (Scopus)

Stout camphor tree genome fills gaps in understanding of flowering plant genome evolution

Chaw, S. M., Liu, Y. C., Wu, Y. W., Wang, H. Y., Lin, C. Y. I., Wu, C. S., Ke, H. M., Chang, L. Y., Hsu, C. Y., Yang, H. T., Sudianto, E., Hsu, M. H., Wu, K. P., Wang, L. N., Leebens-Mack, J. H. & Tsai, I. J., Jan 1 2019, In : Nature Plants. 5, 1, p. 63-73 11 p.

Research output: Contribution to journalArticle

Laurales
camphor
Cinnamomum
Angiospermae
Magnoliales
4 Citations (Scopus)

Straightforward access to biocompatible poly(2-oxazoline)-coated nanomaterials by polymerization-induced self-assembly

Le, D., Wagner, F., Takamiya, M., Hsiao, I-L., Gil Alvaradejo, G., Strähle, U., Weiss, C. & Delaittre, G., Mar 12 2019, In : Chemical Communications.

Research output: Contribution to journalArticle

Nanostructured materials
Self assembly
Polymerization
Cationic polymerization
Ring opening polymerization
1 Citation (Scopus)

Streptolysin S induces mitochondrial damage and macrophage death through inhibiting degradation of glycogen synthase kinase-3β in Streptococcus pyogenes infection

Tsao, N., Kuo, C. F., Cheng, M. H., Lin, W. C., Lin, C. F. & Lin, Y. S., Dec 1 2019, In : Scientific Reports. 9, 1, 5371.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Streptococcus pyogenes
Streptococcus
Macrophages
Infection

Stroke in Parkinson's disease

Huang, Y. F., Yeh, C. C., Chou, Y. C., Hu, C. J., Cherng, Y. G., Shih, C. C., Chen, T. L. & Liao, C. C., Apr 1 2019, In : QJM. 112, 4, p. 269-274 6 p.

Research output: Contribution to journalArticle

Parkinson Disease
Stroke
Confidence Intervals
Odds Ratio
Cohort Studies
2 Citations (Scopus)

Stroke risk and outcomes in epilepsy patients: Two retrospective cohort studies based on National Health Insurance in Taiwan

Hsu, S. P. C., Yeh, C. C., Chou, Y. C., Shih, C. C., Hu, C. J., Cherng, Y. G., Chen, T. L. & Liao, C. C., Jan 1 2019, In : Atherosclerosis. 280, p. 147-154 8 p.

Research output: Contribution to journalArticle

National Health Programs
Taiwan
Epilepsy
Cohort Studies
Retrospective Studies
1 Citation (Scopus)

Structural insights into the interaction between phytoplasmal effector causing phyllody 1 and MADS transcription factors

Liao, Y. T., Lin, S. S., Lin, S. J., Sun, W. T., Shen, B. N., Cheng, H. P., Lin, C. P., Ko, T. P., Chen, Y. F. & Wang, H. C., Jan 1 2019, (Accepted/In press) In : Plant Journal.

Research output: Contribution to journalArticle

Peanut witches'-broom phytoplasma
Phytoplasma
Transcription Factors
transcription factors
surface plasmon resonance
2 Citations (Scopus)

Structural insights to the heterotetrameric interaction between the vibrio parahaemolyticus pirA vp and pirB vp toxins and activation of the cry-like pore-forming domain

Lin, S. J., Chen, Y. F., Hsu, K. C., Chen, Y. L., Ko, T. P., Lo, C. F., Wang, H. C. & Wang, H. C., Apr 1 2019, In : Toxins. 11, 4, 233.

Research output: Contribution to journalArticle

Open Access
Vibrio parahaemolyticus
Penaeidae
Chemical activation
Necrosis
Hepatopancreas
7 Citations (Scopus)

Structure–function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans

Huang, K. Y. A., Rijal, P., Jiang, H., Wang, B., Schimanski, L., Dong, T., Liu, Y. M., Chang, P., Iqbal, M., Wang, M. C., Chen, Z., Song, R., Huang, C. C., Yang, J. H., Qi, J., Lin, T. Y., Li, A., Powell, T. J., Jan, J. T., Ma, C. & 3 others, Gao, G. F., Shi, Y. & Townsend, A. R., Feb 1 2019, In : Nature Microbiology. 4, 2, p. 306-315 10 p.

Research output: Contribution to journalArticle

Neutralizing Antibodies
Human Influenza
Antibodies
Hemagglutinins
Binding Sites

Structure-guided design of anti-cancer ribonucleotide reductase inhibitors

Misko, T. A., Liu, Y. T., Harris, M. E., Oleinick, N. L., Pink, J., Lee, H. Y. & Dealwis, C. G., Jan 1 2019, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 34, 1, p. 438-450 13 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Hydrazones
Neoplasms
Pancreatic Neoplasms
Catalytic Domain
Open Access
Petroselinum
G1 Phase Cell Cycle Checkpoints
Cell Cycle Resting Phase
G1 Phase
Nude Mice
Fibromyalgia
Sleep
Pain
Social Adjustment
Cognition
1 Citation (Scopus)

Subjective wellbeing, suicide and socioeconomic factors: an ecological analysis in Hong Kong

Hsu, C-Y., Chang, S-S. & Yip, P. S. F., Feb 2019, In : Epidemiology and Psychiatric Sciences. 28, 1, p. 112-130 19 p.

Research output: Contribution to journalArticle

Hong Kong
Suicide
Statistical Factor Analysis
Happiness
Population
leflunomide
BK Virus
Kidney Transplantation
Mycophenolic Acid
Transplants
1 Citation (Scopus)
Unsaturated Dietary Fats
Fish Oils
retinoic acid
Tretinoin
fish oils

Surface characterization and thermomechanical behavior of nanostructured-gold layer for biomedical applications

Wu, C. M., Lu, Y. J., Chen, S. Y., Wen, S. C., Wu, C. H., Liao, P. B., Ou, K. L. & Chou, H. H., Apr 25 2019, In : Journal of Alloys and Compounds. 782, p. 1114-1120 7 p.

Research output: Contribution to journalArticle

Gold
Electrodes
Stainless Steel
Electrosurgery
Stainless steel
1 Citation (Scopus)

Surface modification of Ni(OH) 2 nanosheets with PEDOT:PSS for supercapacitor and bendable electrochromic applications

Lee, K. C., Chang-Jian, C. W., Cho, E. C., Huang, J. H., Lin, W. T., Ho, B. C., Chou, J. A. & Hsiao, Y. S., Jun 15 2019, In : Solar Energy Materials and Solar Cells. 195, p. 1-11 11 p.

Research output: Contribution to journalArticle

Nanosheets
Electrochromic devices
Surface treatment
Chemical resistance
Mechanical stability
Open Access
Minimally Invasive Surgical Procedures
Robotics
Rectal Neoplasms
Neoplasms
Length of Stay

Synchronized expressions of serum OPN and BAFF in autoimmune thyroid disease

Cheng, C-W., Tang, K-T., Fang, W-F. & Lin, J-D., Apr 29 2019, In : European Journal of Clinical Investigation. p. e13122

Research output: Contribution to journalArticle

Osteopontin
Thyroid Diseases
Autoimmune Diseases
Hashimoto Disease
Serum

Synergistic cardiac pathological hypertrophy induced by high-salt diet in IGF-IIRα cardiac-specific transgenic rats

Chang, R. L., Nithiyanantham, S., Huang, C. Y., Pai, P. Y., Chang, T. T., Hu, L. C., Chen, R. J., VijayaPadma, V., Kuo, W. W. & Huang, C. Y., Jun 1 2019, In : PLoS ONE. 14, 6, e0216285.

Research output: Contribution to journalArticle

Open Access
Transgenic Rats
Cardiomegaly
Nutrition
hypertrophy
Rats
Lipolysis
Cyclic AMP-Dependent Protein Kinases
Adipocytes
Protein Kinases
Lipase
1 Citation (Scopus)
Urinary Bladder Neoplasms
Antineoplastic Agents
G1 Phase
Ovarian Neoplasms
Solubility
7 Citations (Scopus)
Crohn Disease
Meta-Analysis
Tumor Necrosis Factor-alpha
Incidence
Physiologic Monitoring

Tailor-made iliac branched device for preserving the internal iliac artery in patients with common iliac artery aneurysm

Chen, P-L., Hsu, H-L., Chen, I-M., Kuo, T-T., Chen, Y-Y. & Shih, C-C., Jan 1 2019, In : Journal of the Chinese Medical Association : JCMA. 82, 9, p. 710-713 4 p.

Research output: Contribution to journalArticle

Iliac Aneurysm
Iliac Artery
Stents
Equipment and Supplies
Abdominal Aortic Aneurysm
1 Citation (Scopus)

TARBP2-mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma

Lai, H-H., Li, C-W., Hong, C-C., Sun, H-Y., Chiu, C-F., Ou, D-L. & Chen, P-S., Jan 18 2019, In : Molecular Oncology.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Response Elements
Transcriptional Activation
Hepatocellular Carcinoma
Neoplastic Stem Cells
Open Access
Out-of-Hospital Cardiac Arrest
Middle Cerebral Artery Infarction
Temperature

Targeting myotonic dystrophy by preimplantation genetic diagnosis-karyomapping

Wang, C. W., Liu, Y. L. & Chen, C. H., Jan 1 2019, (Accepted/In press) In : Taiwanese Journal of Obstetrics and Gynecology.

Research output: Contribution to journalArticle

Preimplantation Diagnosis
Myotonic Dystrophy
Genetic Testing
Blastocyst
Genes

Targeting ROS and cPLA2/COX2 Expressions Ameliorated Renal Damage in Obese Mice with Endotoxemia

Chang, J. F., Yeh, J. C., Ho, C. T., Liu, S. H., Hsieh, C. Y., Wang, T. M., Chang, S. W., Lee, I. T., Huang, K. Y., Wang, J. Y. & Lin, W. N., Sep 6 2019, In : International Journal of Molecular Sciences. 20, 18

Research output: Contribution to journalArticle

Open Access
Cytosolic Phospholipases A2
Obese Mice
Endotoxemia
fibrosis
kidneys
1 Citation (Scopus)
Open Access
Osteonectin
Apigenin
Gastropoda
Epithelial-Mesenchymal Transition
Snails

Tea seed oil prevents obesity, reduces physical fatigue, and improves exercise performance in high-fat-diet-induced obese ovariectomized mice

Tung, Y. T., Hsu, Y. J., Chien, Y. W., Huang, C. C., Huang, W. C. & Chiu, W. C., Mar 11 2019, In : Molecules. 24, 5, p. 980 980.

Research output: Contribution to journalArticle

Open Access
obesity
Obese Mice
Oilseeds
diets
Soybean Oil
2 Citations (Scopus)

TET1 promotes 5hmC-dependent stemness, and inhibits a 5hmC-independent epithelial-mesenchymal transition, in cervical precancerous lesions

Su, P. H., Hsu, Y. W., Huang, R. L., Chen, L. Y., Chao, T. K., Liao, C. C., Chen, C. W., Wu, T. I., Mao, S. P., Balch, C. & Lai, H. C., May 28 2019, In : Cancer Letters. 450, p. 53-62 10 p.

Research output: Contribution to journalArticle

Dioxygenases
Epithelial-Mesenchymal Transition
Histones
Gene Silencing
5-Methylcytosine
1 Citation (Scopus)

TET1 reprograms the epithelial ovarian cancer epigenome and reveals casein kinase 2α as a therapeutic target

Chen, L. Y., Huang, R. L., Chan, M. W. Y., Yan, P. S., Huang, T. S., Wu, R. C., Suryo Rahmanto, Y., Su, P. H., Weng, Y. C., Chou, J. L., Chao, T. K., Wang, Y. C., Shih, I. M. & Lai, H. C., Jan 1 2019, In : Journal of Pathology.

Research output: Contribution to journalArticle

Casein Kinase II
Carcinoma
Dioxygenases
Precision Medicine
Immunomodulation
1 Citation (Scopus)

Tetrac and NDAT Induce Anti-proliferation via Integrin αvβ3 in Colorectal Cancers With Different K-RAS Status

Chin, Y-T., He, Z-R., Chen, C-L., Chu, H-C., Ho, Y., Su, P-Y., Yang, Y-C. S. H., Wang, K., Shih, Y-J., Chen, Y-R., Pedersen, J. Z., Incerpi, S., Nana, A. W., Tang, H-Y., Lin, H-Y., Mousa, S. A., Davis, P. J. & Whang-Peng, J., 2019, In : Frontiers in Endocrinology. 10, p. 130

Research output: Contribution to journalArticle

Integrins
Colorectal Neoplasms
HCT116 Cells
Neoplasms
HT29 Cells

TGF-β regulated leukemia cell susceptibility against NK targeting through the down-regulation of the CD48 expression

Huang, C. H., Liao, Y. J., Chiou, T. J., Huang, H. T., Lin, Y. H. & Twu, Y. C., Jan 1 2019, In : Immunobiology.

Research output: Contribution to journalArticle

Transforming Growth Factors
Leukemia
Down-Regulation
Natural Killer Cells
Intercellular Adhesion Molecule-1
1 Citation (Scopus)

The alteration of gut microbiota in newly-diagnosed type 2 diabetic patients

Chen, P-C., Chien, Y-W. & Yang, S-C., Jul 2019, In : Nutrition. 63, p. 51-56

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Clostridium
Lactobacillus
Dysbiosis
Therapeutics
2 Citations (Scopus)

The Ambivalent Role of lncRNA Xist in Carcinogenesis

Chen, Y. K. & Yen, Y., Apr 15 2019, In : Stem Cell Reviews and Reports. 15, 2, p. 314-323 10 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
X Chromosome Inactivation
Carcinogenesis
Neoplasms
X Chromosome

The antipsychotic chlorpromazine suppresses YAP signaling, stemness properties, and drug resistance in breast cancer cells

Yang, C. E., Lee, W. Y., Cheng, H. W., Chung, C. H., Mi, F. L. & Lin, C. W., Apr 1 2019, In : Chemico-Biological Interactions. 302, p. 28-35 8 p.

Research output: Contribution to journalArticle

Chlorpromazine
Drug Resistance
Antipsychotic Agents
Stem cells
Cells
2 Citations (Scopus)
Periodontal Pocket
Tooth Root
Endodontics
Abscess
Logistic Models

The association between fecal hemoglobin concentration and oral potentially malignant disorders

Yen, A. M. F., Wang, S. T., Feng, S. W., Lin, C. T. & Chen, S. L. S., Jan 1 2019, In : Oral Diseases. 25, 1, p. 108-116 9 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Hemoglobins
Early Detection of Cancer
Longitudinal Studies
Colorectal Neoplasms
1 Citation (Scopus)
Selenium
Arsenic
Cadmium
selenium
Chronic Renal Insufficiency

The association between psychological distress and angina pectoris: A population-based study

Tsai, C. C., Chuang, S. Y., Hsieh, I. C., Ho, L. H., Chu, P. H. & Jeng, C., Jan 1 2019, In : PLoS ONE. 14, 11, e0224451.

Research output: Contribution to journalArticle

Open Access
Angina Pectoris
Nutrition
distress
Health care
Metabolism