Find Research Outputs

2020

Abnormal Functional Relationship of Sensorimotor Network With Neurotransmitter-Related Nuclei via Subcortical-Cortical Loops in Manic and Depressive Phases of Bipolar Disorder

Martino, M., Magioncalda, P., Conio, B., Capobianco, L., Russo, D., Adavastro, G., Tumati, S., Tan, Z., Lee, H-C., Lane, T. J., Amore, M., Inglese, M. & Northoff, G., Jan 4 2020, In : Schizophrenia Bulletin. 46, 1, p. 163-174 12 p.

Research output: Contribution to journalArticle

Thalamus
Bipolar Disorder
Neurotransmitter Agents
Raphe Nuclei
Basal Ganglia

A cost-effectiveness analysis of trastuzumab-containing treatment sequences for HER-2 positive metastatic breast cancer patients in Taiwan

Diaby, V., Alqhtani, H., van Boemmel-Wegmann, S., Wang, C. Y., Ali, A. A., Balkrishnan, R., Ko, Y., Palacio, S. & de Lima Lopes, G., Feb 1 2020, In : Breast. 49, p. 141-148 8 p.

Research output: Contribution to journalArticle

Open Access
docetaxel
Taiwan
Cost-Benefit Analysis
Breast Neoplasms
National Health Programs

A multicenter, phase I/II trial of biweekly S-1, leucovorin, oxaliplatin and gemcitabine in metastatic pancreatic adenocarcinoma–TCOG T1211 study

Chiang, N. J., Tsai, K. K., Hsiao, C. F., Yang, S. H., Hsiao, H. H., Shen, W. C., Hsu, C., Lin, Y. L., Chen, J. S., Shan, Y. S. & Chen, L. T., Jan 2020, In : European Journal of Cancer. 124, p. 123-130 8 p.

Research output: Contribution to journalArticle

oxaliplatin
gemcitabine
Leucovorin
Adenocarcinoma
irinotecan

An assessment of the psychometric properties of the Chinese version of the Gout Impact Scale

Pao, C. H. & Ko, Y., Jan 2 2020, In : Current Medical Research and Opinion. 36, 1, p. 17-21 5 p.

Research output: Contribution to journalArticle

Gout
Psychometrics

Association of Time-Varying Rest-Activity Rhythm With Survival in Older Adults With Lung Cancer

Kuo, L. C., Chang, W. P., Huang, H. C. & Lin, C. C., Jan 1 2020, In : Cancer Nursing. 43, 1, p. 45-51 7 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Survival
Proportional Hazards Models
Actigraphy
Disease Progression

Aza-PBHA, a potent histone deacetylase inhibitor, inhibits human gastric-cancer cell migration via PKCα-mediated AHR-HDAC interactions

Tsai, C. H., Li, C. H., Liao, P. L., Chang, Y. W., Cheng, Y. W. & Kang, J. J., Feb 2020, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1867, 2, 118564.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Histone Deacetylase Inhibitors
Histone Deacetylases
Stomach Neoplasms
Cell Movement

Comparison of the predictive outcomes for anti-tuberculosis drug-induced hepatotoxicity by different machine learning techniques

Lai, N. H., Shen, W. C., Lee, C. N., Chang, J. C., Hsu, M. C., Kuo, L. N., Yu, M. C. & Chen, H. Y., May 2020, In : Computer Methods and Programs in Biomedicine. 188, 105307.

Research output: Contribution to journalArticle

Learning systems
Tuberculosis
Neural networks
ROC Curve
Support vector machines

Controlled Tactile and Vibration Feedback Embedded in a Smart Knee Brace

Hsu, W. C., Sugiarto, T., Wu, J. L., Lin, Y. J., Lin, L. F., Tsai, C. Y., Chang, C. C., Hsieh, Z. R. & Lee, Y. H., Jan 1 2020, IEEE Consumer Electronics Magazine, 9, 1, p. 54-60 7 p.

Research output: Contribution to specialist publicationArticle

Muscle
Feedback
Chemical activation
Electromyography
Sensors

Disturbed Gastrointestinal Contractility in a Polycystic Ovary Syndrome Rat Model

Wang, K. L., Hsia, S. M., Wang, P. S. & Lin, P. H., Jan 1 2020, (Accepted/In press) In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Acetylcholine
Stomach
Colon
Carbachol

Dramatically enhanced mechanical properties of diamond-like carbon films on polymer substrate for flexible display devices via argon plasma pretreatment

Lee, J. A., Lin, C. R., Pan, P. C., Liu, C. W. & Sun, A. Y. T., Jan 15 2020, In : Chemical Physics. 529, 110551.

Research output: Contribution to journalArticle

Flexible displays
Diamond like carbon films
Argon
argon plasma
display devices
Health Literacy
Health Status
Rehabilitation
Randomized Controlled Trials
Breast Neoplasms

Effect of cell culture biomaterials for completely xeno-free generation of human induced pluripotent stem cells

Sung, T. C., Li, H. F., Higuchi, A., Kumar, S. S., Ling, Q. D., Wu, Y. W., Burnouf, T., Nasu, M., Umezawa, A., Lee, K. F., Wang, H. C., Chang, Y. & Hsu, S. T., Feb 2020, In : Biomaterials. 230, 119638.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Biocompatible Materials
Amniotic Fluid
Stem cells
Cell culture
Open Access

Fish oil up-regulates hepatic autophagy in rats with chronic ethanol consumption

Lu, N. S., Chiu, W. C., Chen, Y. L., Peng, H. C., Shirakawa, H. & Yang, S. C., Mar 2020, In : Journal of Nutritional Biochemistry. 77, 108314.

Research output: Contribution to journalArticle

Fish Oils
Autophagy
Rats
Ethanol
Up-Regulation

Gender differences in the relationships between sleep disturbances and academic performance among nursing students: A cross-sectional study

Marta, O. F. D., Kuo, S. Y., Bloomfield, J., Lee, H. C., Ruhyanudin, F., Poynor, M. Y., Brahmadhi, A., Pratiwi, I. D., Aini, N., Mashfufa, E. W., Hasan, F. & Chiu, H. Y., Feb 2020, In : Nurse Education Today. 85, 104270.

Research output: Contribution to journalArticle

Nursing Students
sleep
cross-sectional study
gender-specific factors
Sleep

Histone 2A family member j drives mesenchymal transition and temozolomide resistance in glioblastoma multiforme

Lee, H. H., Lin, C. H., Lin, H. Y., Kuei, C. H., Zheng, J. Q., Wang, Y. H., Lu, L. S., Lee, F. P., Hu, C. J., Wu, D. & Lin, Y. F., Jan 2020, In : Cancers. 12, 1, 98.

Research output: Contribution to journalArticle

Open Access
temozolomide
Glioblastoma
Histones
Interleukin-6
Up-Regulation

Individual Alpha Frequency Predicts Perceived Visuotactile Simultaneity

Migliorati, D., Zappasodi, F., Perrucci, M. G., Donno, B., Northoff, G., Romei, V. & Costantini, M., Jan 1 2020, In : Journal of Cognitive Neuroscience. 32, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

Parietal Lobe
Population
Power (Psychology)

Intercalating pyrene with polypeptide as a novel self-assembly nano-carrier for colon cancer suppression in vitro and in vivo

Lo, P. Y., Lee, G. Y., Zheng, J. H., Huang, J. H., Cho, E. C. & Lee, K. C., Apr 1 2020, In : Materials Science and Engineering C. 109, 110593.

Research output: Contribution to journalArticle

Polypeptides
Pyrene
polypeptides
pyrenes
Self assembly

In vitro and in vivo evaluation of the neuroprotective activity of Uncaria hirsuta Haviland

Lin, C. M., Lin, Y. T., Lee, T. L., Imtiyaz, Z., Hou, W. C. & Lee, M. H., Jan 2020, In : Journal of Food and Drug Analysis. 28, 1, p. 147-158 12 p.

Research output: Contribution to journalArticle

Open Access
Uncaria
neuroprotective effect
Inhibitory Concentration 50
inhibitory concentration 50
Oxidopamine

LMP1 gene detection using a capped gold nanowire array surface plasmon resonance sensor in a microfluidic chip

Chuang, C-S., Wu, C-Y., Juan, P-H., Hou, N-C., Fan, Y-J., Wei, P-K. & Sheen, H-J., 2020, In : Analyst.

Research output: Contribution to journalArticle

Mammalian target of rapamycin and p70S6K mediate thrombin-induced nuclear factor-κB activation and IL-8/CXCL8 release in human lung epithelial cells

Lin, C. H., Shih, C. H., Jiang, C. P., Wen, H. C., Cheng, W. H. & Chen, B. C., Feb 5 2020, In : European Journal of Pharmacology. 868, 172879.

Research output: Contribution to journalArticle

Complement Factor B
Sirolimus
Interleukin-8
Thrombin
Phosphotransferases

Measurement of resilience potentials in emergency departments: Applications of a tailored resilience assessment grid

Chuang, S., Ou, J. C. & Ma, H. P., Jan 1 2020, In : Safety Science. 121, p. 385-393 9 p.

Research output: Contribution to journalArticle

resilience
Hospital Emergency Service
Hospital Departments
Interviews
Health care

Melatonin activates cell death programs for the suppression of uterine leiomyoma cell proliferation

Lin, P. H., Tung, Y. T., Chen, H. Y., Chiang, Y. F., Hong, H. C., Huang, K. C., Hsu, S. P., Huang, T. C. & Hsia, S. M., Jan 1 2020, In : Journal of Pineal Research. 68, 1, e12620.

Research output: Contribution to journalArticle

Leiomyoma
Melatonin
Cell Death
Cell Proliferation
Myometrium
1 Citation (Scopus)

Multimodal Magnetic Resonance Imaging Data Fusion Reveals Distinct Patterns of Abnormal Brain Structure and Function in Catatonia

Hirjak, D., Rashidi, M., Kubera, K. M., Northoff, G., Fritze, S., Schmitgen, M. M., Sambataro, F., Calhoun, V. D. & Wolf, R. C., Jan 4 2020, In : Schizophrenia Bulletin. 46, 1, p. 202-210 9 p.

Research output: Contribution to journalArticle

Catatonia
Magnetic Resonance Imaging
Brain
Schizophrenia

Music, heart rate variability, and symptom clusters: a comparative study

Chen, S. C., Yeh, M. L., Chang, H. J. & Lin, M. F., Jan 1 2020, In : Supportive Care in Cancer. 28, 1, p. 351-360 10 p.

Research output: Contribution to journalArticle

Music
Heart Rate
Breast Neoplasms
Control Groups
Fatigue
1 Citation (Scopus)

N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression

Mehndiratta, S., Lin, M. H., Wu, Y. W., Chen, C. H., Wu, T. Y., Chuang, K. H., Chao, M. W., Chen, Y. Y., Pan, S. L., Chen, M. C. & Liou, J. P., Jan 1 2020, In : European Journal of Medicinal Chemistry. 185, p. 111725 111725.

Research output: Contribution to journalArticle

Anilides
HSP90 Heat-Shock Proteins
Histone Deacetylase Inhibitors
Histone Deacetylases
Down-Regulation

NDAT suppresses pro-inflammatory gene expression to enhance resveratrol-induced anti-proliferation in oral cancer cells

Ho, Y., Wu, C. Y., Chin, Y. T., Li, Z. L., Pan, Y. S., Huang, T. Y., Su, P. Y., Lee, S. Y., Crawford, D. R., Su, K. W., Chiu, H. C., Shih, Y. J., Changou, C. A., Yang, Y. C. S. H., Whang-Peng, J., Chen, Y. R., Lin, H. Y., Mousa, S. A., Davis, P. J. & Wang, K., Feb 2020, In : Food and Chemical Toxicology. 136, 111092.

Research output: Contribution to journalArticle

Optimal measuring timing of cystatin C for early detection of contrast-induced acute kidney injury: A systematic review and meta-analysis

Chen, C. T., Chang, L. Y., Chuang, C. W., Wang, S. C., Kao, M. C., Tzeng, I. S., Kuo, K. L., Wu, C. C., Tsai, P. S. & Huang, C. J., Jan 2020, In : Toxicology Letters. 318, p. 65-73 9 p.

Research output: Contribution to journalArticle

Cystatin C
Acute Kidney Injury
Meta-Analysis
Contrast Media
Peripheral Catheterization
Nanofibers
Hydrogel
Hydrogels
Scaffolds
Suspensions

Progressive muscle relaxation for patients with chronic schizophrenia: A randomized controlled study

Lu, S-M., Lin, M-F. & Chang, H-J., Jan 1 2020, In : Perspectives in Psychiatric Care. 56, 1, p. 86-94 9 p.

Research output: Contribution to journalArticle

Autogenic Training
Schizophrenia
Psychiatry
Anxiety
Quality of Life

Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment

Kaur, N., Fang, Y. C., Lee, H. Y., Singh, A., Nepali, K., Lin, M. H., Yeh, T. K., Lai, M. J., Chan, L., Tu, Y. K., Banerjee, S., Hu, C. J. & Liou, J. P., Feb 1 2020, In : European Journal of Medicinal Chemistry. 187, 111915.

Research output: Contribution to journalArticle

Azepines
Histone Deacetylase Inhibitors
Blood Vessels
Acetylation
Acrylamide

Steering the antitumor drug discovery campaign towards structurally diverse indolines

Thakur, A., Singh, A., Kaur, N., Ojha, R. & Nepali, K., Jan 2020, In : Bioorganic Chemistry. 94, 103436.

Research output: Contribution to journalReview article

Drug Discovery
Antineoplastic Agents
Scaffolds
Magic
Structure-Activity Relationship

Synbiotic combination of djulis (Chenopodium formosanum) and lactobacillus acidophilus inhibits colon carcinogenesis in rats

Lee, C. W., Chen, H. J., Chien, Y. H., Hsia, S. M., Chen, J. H. & Shih, C. K., Jan 2020, In : Nutrients. 12, 1, 103.

Research output: Contribution to journalArticle

Open Access
Chenopodium
Synbiotics
Lactobacillus acidophilus
carcinogenesis
colon

The Antibacterial Efficacy and In Vivo Toxicity of Sodium Hypochlorite and Electrolyzed Oxidizing (EO) Water-Based Endodontic Irrigating Solutions

Hsieh, S-C., Teng, N-C., Chu, C. C., Chu, Y-T., Chen, C-H., Chang, L-Y., Hsu, C-Y., Huang, C-S., Hsiao, G. Y-W. & Yang, J-C., Jan 7 2020, In : Materials. 13, 2

Research output: Contribution to journalArticle

Hypochlorous Acid
Sodium Hypochlorite
Toxicity
Sodium
Acids

Vitamin B12 deficiency and metabolism-mediated thrombotic microangiopathy (MM-TMA)

Sabry, W., Elemary, M., Burnouf, T., Seghatchian, J. & Goubran, H., Jan 1 2020, (Accepted/In press) In : Transfusion and Apheresis Science. 102717.

Research output: Contribution to journalReview article

Thrombotic Microangiopathies
Vitamin B 12 Deficiency
Vitamin B 12
Reticulocytosis
Erythrocyte Indices
2019
Calcitriol
Granulosa Cells
Phosphatidylinositol 3-Kinases
Rats
Estradiol
5 Citations (Scopus)

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journalArticle

Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50
3 Citations (Scopus)

2019 consensus statement of the Taiwan hypertension society and the Taiwan society of cardiology on renal denervation for the management of arterial hypertension

Wang, T. D., Lee, Y. H., Chang, S. S., Tung, Y. C., Yeh, C. F., Lin, Y. H., Pan, C. T., Hsu, C. Y., Huang, C. Y., Wu, C. K., Sung, P. H., Chiang, L. T., Wang, Y. C., Tsai, W. C., Lin, T. T., Lin, C. P., Chen, W. J. & Hwang, J. J., May 1 2019, In : Acta Cardiologica Sinica. 35, 3, p. 199-230 32 p.

Research output: Contribution to journalArticle

Denervation
Cardiology
Taiwan
Hypertension
Kidney

2019 focused update of the guidelines of the Taiwan society of cardiology for the diagnosis and treatment of heart failure

Wang, C. C., Wu, C. K., Tsai, M. L., Lee, C. M., Huang, W. C., Chou, H. H., Huang, J. L., Chi, N. H., Yen, H. W., Tzeng, B. H., Chang, W. T., Chang, H. Y., Wang, C. H., Lu, Y. Y., Tsai, J. P., Su, C. H., Cherng, W. J., Yin, W. H., Tsai, C. T., Wu, Y. W. & 2 others, Lin, J-L. & Hwang, J. J., May 1 2019, In : Acta Cardiologica Sinica. 35, 3, p. 244-283 40 p.

Research output: Contribution to journalArticle

Cardiology
Treatment Failure
Taiwan
Heart Failure
Guidelines
1 Citation (Scopus)

6,7-dihydroxy-2-(4′-hydroxyphenyl)naphthalene induces HCT116 cell apoptosis through activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway

Chiu, C. F., Lai, G. Y., Chen, C. H., Chiu, C. C., Hung, S. W. & Chang, C. F., Jan 1 2019, In : Drug Design, Development and Therapy. 13, p. 1609-1621 13 p.

Research output: Contribution to journalArticle

Open Access
HCT116 Cells
Endoplasmic Reticulum Stress
Colorectal Neoplasms
Apoptosis
Cyclin B

A bioinspired hyperthermic macrophage-based polypyrrole-polyethylenimine (Ppy-PEI) nanocomplex carrier to prevent and disrupt thrombotic fibrin clots

Burnouf, T., Chen, C. H., Tan, S. J., Tseng, C. L., Lu, K. Y., Chang, L. H., Nyambat, B., Huang, S. C., Jheng, P. R., Aditya, R. N., Mi, F. L. & Chuang, E. Y., Sep 15 2019, In : Acta Biomaterialia. 96, p. 468-479 12 p.

Research output: Contribution to journalArticle

Polyethyleneimine
Macrophages
Polypyrroles
Fibrin
Radiation
Stents
Coronary Angiography
Optical Coherence Tomography
Hematoma
Dissection
Return to Work
Appointments and Schedules
Rehabilitation
ROC Curve
Traumatic Brain Injury

Accuracy of cone beam computed tomography in measuring thicknesses of hard-tissue-mimicking material adjacent to different implant thread surfaces

Yen, C. Y., Kuo, P. J., Lin, C. Y., Nie-Shiuh Chang, N., Hsiao, H. Y., Chin, Y. T., Tsai, C. C. & Lee, S. Y., Jun 1 2019, In : Journal of Dental Sciences. 14, 2, p. 119-125 7 p.

Research output: Contribution to journalArticle

Open Access
Cone-Beam Computed Tomography
Dental Implants
Neck
Open Access
Malawi
Insecticides
Health Services
Public Health
Cross-Sectional Studies

A critical period for the development of schizophrenia-like pathology by aberrant postnatal neurogenesis

Sheu, J. R., Hsieh, C. Y., Jayakumar, T., Tseng, M. F., Lee, H. N., Huang, S. W., Manubolu, M. & Yang, C. H., Jan 1 2019, In : Frontiers in Neuroscience. 13, JUN, 635.

Research output: Contribution to journalArticle

Open Access
Neurogenesis
Schizophrenia
Pathology
Critical Period (Psychology)
Hallucinations
2 Citations (Scopus)

A Cross-Sectional Study of Endogenous Antioxidants and Patterns of Dental Visits of Periodontitis Patients

Lee, C. Y., Choy, C. S., Lai, Y. C., Chang, C. C., Teng, N. C., Huang, W. T., Lin, C. T. & Huang, Y. K., Jan 9 2019, In : International Journal of Environmental Research and Public Health. 16, 2

Research output: Contribution to journalArticle

Periodontitis
Tooth
Cross-Sectional Studies
Antioxidants
Oral Health
1 Citation (Scopus)

Action of Reverse T3 on Cancer Cells

Lin, H. Y., Tang, H. Y., Leinung, M., Mousa, S. A., Hercbergs, A. & Davis, P. J., Jan 1 2019, In : Endocrine Research.

Research output: Contribution to journalArticle

Integrins
Thyronines
Thyroid Hormone Receptors
Neoplasms
Glioblastoma
Curcumin
Endothelin-1
Fibroblasts
Thrombin
Phosphotransferases